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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF257
Full Name:
Alias:
Bone marrow zinc finger 4
Type:
Mass (Da):
62348
Number AA:
535
UniProt ID:
Q9Y2Q1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
P
L
T
I
R
D
V
T
V
E
F
S
L
E
E
Site 2
Y29
D
T
A
Q
Q
N
L
Y
R
D
V
M
L
E
N
Site 3
Y93
C
P
E
R
D
I
K
Y
F
F
Q
K
V
I
L
Site 4
Y103
Q
K
V
I
L
R
R
Y
D
K
C
E
H
E
N
Site 5
S119
Q
L
R
K
G
C
K
S
V
D
E
C
K
V
C
Site 6
Y150
K
M
Y
Q
C
D
K
Y
V
K
V
F
Y
K
F
Site 7
S158
V
K
V
F
Y
K
F
S
N
S
D
R
H
K
I
Site 8
T168
D
R
H
K
I
R
H
T
E
K
K
T
C
K
C
Site 9
S185
C
G
K
A
F
N
Q
S
S
A
L
T
R
H
K
Site 10
S186
G
K
A
F
N
Q
S
S
A
L
T
R
H
K
M
Site 11
T189
F
N
Q
S
S
A
L
T
R
H
K
M
T
H
T
Site 12
S213
C
G
K
A
F
N
R
S
S
H
L
T
Q
H
K
Site 13
S214
G
K
A
F
N
R
S
S
H
L
T
Q
H
K
V
Site 14
T217
F
N
R
S
S
H
L
T
Q
H
K
V
I
H
T
Site 15
S242
G
K
A
F
N
R
S
S
H
I
T
Q
H
K
R
Site 16
Y259
N
R
E
K
P
F
K
Y
D
E
C
C
K
A
F
Site 17
T273
F
K
W
S
S
A
L
T
T
L
T
Q
H
K
R
Site 18
T274
K
W
S
S
A
L
T
T
L
T
Q
H
K
R
I
Site 19
T276
S
S
A
L
T
T
L
T
Q
H
K
R
I
H
T
Site 20
T283
T
Q
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 21
T304
F
N
Q
S
S
A
L
T
R
H
K
M
I
H
T
Site 22
T311
T
R
H
K
M
I
H
T
G
E
K
P
F
Q
C
Site 23
S329
G
K
A
F
N
R
S
S
H
L
T
Q
H
K
I
Site 24
T332
F
N
R
S
S
H
L
T
Q
H
K
I
I
H
T
Site 25
T339
T
Q
H
K
I
I
H
T
K
E
K
P
Y
K
C
Site 26
S356
C
G
K
A
F
N
R
S
S
H
L
T
K
H
K
Site 27
S357
G
K
A
F
N
R
S
S
H
L
T
K
H
K
R
Site 28
T360
F
N
R
S
S
H
L
T
K
H
K
R
I
H
T
Site 29
T367
T
K
H
K
R
I
H
T
R
E
K
A
Y
K
C
Site 30
T388
F
N
W
S
S
A
L
T
T
L
T
Q
H
K
I
Site 31
T389
N
W
S
S
A
L
T
T
L
T
Q
H
K
I
I
Site 32
T391
S
S
A
L
T
T
L
T
Q
H
K
I
I
H
T
Site 33
S416
G
K
A
F
N
R
S
S
Y
L
I
R
H
E
I
Site 34
Y417
K
A
F
N
R
S
S
Y
L
I
R
H
E
I
I
Site 35
T426
I
R
H
E
I
I
H
T
G
E
K
P
Y
K
C
Site 36
S444
G
K
A
F
N
Q
S
S
H
L
T
Q
H
K
I
Site 37
T447
F
N
Q
S
S
H
L
T
Q
H
K
I
I
H
T
Site 38
S471
C
G
K
A
F
N
R
S
S
Q
P
S
Q
H
R
Site 39
S472
G
K
A
F
N
R
S
S
Q
P
S
Q
H
R
I
Site 40
S475
F
N
R
S
S
Q
P
S
Q
H
R
I
I
H
T
Site 41
T482
S
Q
H
R
I
I
H
T
G
E
K
P
Y
K
C
Site 42
T498
E
C
G
K
A
F
N
T
F
S
Y
L
T
V
H
Site 43
S500
G
K
A
F
N
T
F
S
Y
L
T
V
H
K
R
Site 44
Y501
K
A
F
N
T
F
S
Y
L
T
V
H
K
R
I
Site 45
Y517
A
G
E
N
P
N
K
Y
E
E
C
G
K
A
C
Site 46
S528
G
K
A
C
N
H
S
S
N
L
T
K
H
N
S
Site 47
T531
C
N
H
S
S
N
L
T
K
H
N
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation