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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX52
Full Name:
DEAD box protein 52
Alias:
ATP-dependent RNA helicase; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; EC 3.6.1.-; HUSSY-19; Probable ATP-dependent RNA helicase DDX52; ROK1
Type:
Helicase
Mass (Da):
67466
Number AA:
599
UniProt ID:
Q9Y2R4
International Prot ID:
IPI00032423
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008026
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
G
A
G
A
K
F
D
T
R
R
F
S
A
D
A
Site 2
S22
K
F
D
T
R
R
F
S
A
D
A
A
R
F
Q
Site 3
Y35
F
Q
I
G
K
R
K
Y
D
F
D
S
S
E
V
Site 4
S39
K
R
K
Y
D
F
D
S
S
E
V
L
Q
G
L
Site 5
S40
R
K
Y
D
F
D
S
S
E
V
L
Q
G
L
D
Site 6
S54
D
F
F
G
N
K
K
S
V
P
G
V
C
G
A
Site 7
S77
N
G
E
K
K
E
E
S
L
T
E
R
K
R
E
Site 8
T79
E
K
K
E
E
S
L
T
E
R
K
R
E
Q
S
Site 9
S86
T
E
R
K
R
E
Q
S
K
K
K
R
K
T
M
Site 10
T92
Q
S
K
K
K
R
K
T
M
T
S
E
I
A
S
Site 11
S95
K
K
R
K
T
M
T
S
E
I
A
S
Q
E
E
Site 12
S99
T
M
T
S
E
I
A
S
Q
E
E
G
A
T
I
Site 13
T105
A
S
Q
E
E
G
A
T
I
Q
W
M
S
S
V
Site 14
S110
G
A
T
I
Q
W
M
S
S
V
E
A
K
I
E
Site 15
S111
A
T
I
Q
W
M
S
S
V
E
A
K
I
E
D
Site 16
S125
D
K
K
V
Q
R
E
S
K
L
T
S
G
K
L
Site 17
T128
V
Q
R
E
S
K
L
T
S
G
K
L
E
N
L
Site 18
S129
Q
R
E
S
K
L
T
S
G
K
L
E
N
L
R
Site 19
Y170
F
Q
Q
L
D
Q
E
Y
K
I
N
S
R
L
L
Site 20
S208
H
G
R
E
L
L
A
S
A
P
T
G
S
G
K
Site 21
S248
S
P
T
R
E
L
A
S
Q
I
H
R
E
L
I
Site 22
S282
A
K
K
F
G
P
K
S
S
K
K
F
D
I
L
Site 23
T291
K
K
F
D
I
L
V
T
T
P
N
R
L
I
Y
Site 24
T292
K
F
D
I
L
V
T
T
P
N
R
L
I
Y
L
Site 25
Y298
T
T
P
N
R
L
I
Y
L
L
K
Q
D
P
P
Site 26
S320
E
W
L
V
V
D
E
S
D
K
L
F
E
D
G
Site 27
T329
K
L
F
E
D
G
K
T
G
F
R
D
Q
L
A
Site 28
T355
R
R
A
M
F
S
A
T
F
A
Y
D
V
E
Q
Site 29
S381
V
S
I
G
A
R
N
S
A
V
E
T
V
E
Q
Site 30
T385
A
R
N
S
A
V
E
T
V
E
Q
E
L
L
F
Site 31
T454
T
Q
Q
Q
R
D
N
T
V
H
S
F
R
A
G
Site 32
T491
V
I
N
Y
D
F
P
T
S
S
V
E
Y
I
H
Site 33
Y496
F
P
T
S
S
V
E
Y
I
H
R
I
G
R
T
Site 34
T514
G
N
K
G
K
A
I
T
F
F
T
E
D
D
K
Site 35
T517
G
K
A
I
T
F
F
T
E
D
D
K
P
L
L
Site 36
S526
D
D
K
P
L
L
R
S
V
A
N
V
I
Q
Q
Site 37
Y541
A
G
C
P
V
P
E
Y
I
K
G
F
Q
K
L
Site 38
S550
K
G
F
Q
K
L
L
S
K
Q
K
K
K
M
I
Site 39
S565
K
K
P
L
E
R
E
S
I
S
T
T
P
K
C
Site 40
T568
L
E
R
E
S
I
S
T
T
P
K
C
F
L
E
Site 41
T569
E
R
E
S
I
S
T
T
P
K
C
F
L
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation