KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PPP2R2C
Full Name:
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
Alias:
2ABG; IMYPNO; IMYPNO1; PR52; PR55G; Protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform
Type:
Protein phosphatase regulatory subunit
Mass (Da):
51515
Number AA:
447
UniProt ID:
Q9Y2T4
International Prot ID:
IPI00032462
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000159
Uniprot
OncoNet
Molecular Function:
GO:0008601
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
D
T
R
K
I
N
H
S
F
L
R
D
H
S
Y
Site 2
S19
H
S
F
L
R
D
H
S
Y
V
T
E
A
D
I
Site 3
Y20
S
F
L
R
D
H
S
Y
V
T
E
A
D
I
I
Site 4
T35
S
T
V
E
F
N
H
T
G
E
L
L
A
T
G
Site 5
T41
H
T
G
E
L
L
A
T
G
D
K
G
G
R
V
Site 6
S57
I
F
Q
R
E
P
E
S
K
N
A
P
H
S
Q
Site 7
S63
E
S
K
N
A
P
H
S
Q
G
E
Y
D
V
Y
Site 8
Y67
A
P
H
S
Q
G
E
Y
D
V
Y
S
T
F
Q
Site 9
Y70
S
Q
G
E
Y
D
V
Y
S
T
F
Q
S
H
E
Site 10
S71
Q
G
E
Y
D
V
Y
S
T
F
Q
S
H
E
P
Site 11
Y82
S
H
E
P
E
F
D
Y
L
K
S
L
E
I
E
Site 12
S85
P
E
F
D
Y
L
K
S
L
E
I
E
E
K
I
Site 13
S106
P
Q
Q
N
A
A
H
S
L
L
S
T
N
D
K
Site 14
S109
N
A
A
H
S
L
L
S
T
N
D
K
T
I
K
Site 15
T110
A
A
H
S
L
L
S
T
N
D
K
T
I
K
L
Site 16
T114
L
L
S
T
N
D
K
T
I
K
L
W
K
I
T
Site 17
S143
E
G
K
L
K
D
L
S
T
V
T
S
L
Q
V
Site 18
T144
G
K
L
K
D
L
S
T
V
T
S
L
Q
V
P
Site 19
S183
I
N
S
I
S
V
N
S
D
C
E
T
Y
M
S
Site 20
T187
S
V
N
S
D
C
E
T
Y
M
S
A
D
D
L
Site 21
S190
S
D
C
E
T
Y
M
S
A
D
D
L
R
I
N
Site 22
T222
P
A
N
M
E
D
L
T
E
V
I
T
A
S
E
Site 23
T226
E
D
L
T
E
V
I
T
A
S
E
F
H
P
H
Site 24
Y240
H
H
C
N
L
F
V
Y
S
S
S
K
G
S
L
Site 25
S241
H
C
N
L
F
V
Y
S
S
S
K
G
S
L
R
Site 26
S246
V
Y
S
S
S
K
G
S
L
R
L
C
D
M
R
Site 27
S262
A
A
L
C
D
K
H
S
K
L
F
E
E
P
E
Site 28
S272
F
E
E
P
E
D
P
S
N
R
S
F
F
S
E
Site 29
S275
P
E
D
P
S
N
R
S
F
F
S
E
I
I
S
Site 30
S278
P
S
N
R
S
F
F
S
E
I
I
S
S
V
S
Site 31
S285
S
E
I
I
S
S
V
S
D
V
K
F
S
H
S
Site 32
S292
S
D
V
K
F
S
H
S
G
R
Y
M
L
T
R
Site 33
Y301
R
Y
M
L
T
R
D
Y
L
T
V
K
V
W
D
Site 34
T303
M
L
T
R
D
Y
L
T
V
K
V
W
D
L
N
Site 35
T318
M
E
A
R
P
I
E
T
Y
Q
V
H
D
Y
L
Site 36
Y319
E
A
R
P
I
E
T
Y
Q
V
H
D
Y
L
R
Site 37
Y324
E
T
Y
Q
V
H
D
Y
L
R
S
K
L
C
S
Site 38
S327
Q
V
H
D
Y
L
R
S
K
L
C
S
L
Y
E
Site 39
S331
Y
L
R
S
K
L
C
S
L
Y
E
N
D
C
I
Site 40
Y333
R
S
K
L
C
S
L
Y
E
N
D
C
I
F
D
Site 41
T369
F
R
M
F
D
R
N
T
K
R
D
V
T
L
E
Site 42
T374
R
N
T
K
R
D
V
T
L
E
A
S
R
E
S
Site 43
S378
R
D
V
T
L
E
A
S
R
E
S
S
K
P
R
Site 44
S381
T
L
E
A
S
R
E
S
S
K
P
R
A
V
L
Site 45
S382
L
E
A
S
R
E
S
S
K
P
R
A
V
L
K
Site 46
S405
K
R
R
R
D
D
I
S
V
D
S
L
D
F
T
Site 47
S408
R
D
D
I
S
V
D
S
L
D
F
T
K
K
I
Site 48
T412
S
V
D
S
L
D
F
T
K
K
I
L
H
T
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation