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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTO1
Full Name:
Protein MTO1 homolog, mitochondrial
Alias:
mitochondrial MTO1-3; mitochondrial translation optimization 1
Type:
RNA processing
Mass (Da):
79964
Number AA:
717
UniProt ID:
Q9Y2Z2
International Prot ID:
IPI00032630
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0009055
GO:0016491
PhosphoSite+
KinaseNET
Biological Process:
GO:0008033
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
Q
F
P
L
A
R
L
S
S
D
S
A
A
P
R
Site 2
S27
F
P
L
A
R
L
S
S
D
S
A
A
P
R
T
Site 3
S29
L
A
R
L
S
S
D
S
A
A
P
R
T
P
H
Site 4
T34
S
D
S
A
A
P
R
T
P
H
F
D
V
I
V
Site 5
T66
G
S
R
T
L
L
L
T
H
R
V
D
T
I
G
Site 6
T71
L
L
T
H
R
V
D
T
I
G
Q
M
S
C
N
Site 7
S76
V
D
T
I
G
Q
M
S
C
N
P
S
F
G
G
Site 8
S80
G
Q
M
S
C
N
P
S
F
G
G
I
G
K
G
Site 9
S101
D
A
L
D
G
L
C
S
R
I
C
D
Q
S
G
Site 10
Y111
C
D
Q
S
G
V
H
Y
K
V
L
N
R
R
K
Site 11
Y134
A
Q
I
D
R
K
L
Y
K
Q
N
M
Q
K
E
Site 12
T145
M
Q
K
E
I
L
N
T
P
L
L
T
V
Q
E
Site 13
T168
T
E
P
E
P
E
H
T
G
K
C
R
V
S
G
Site 14
S218
G
R
L
G
D
Q
P
S
I
G
L
A
Q
T
L
Site 15
T239
V
G
R
L
K
T
G
T
P
P
R
I
A
K
E
Site 16
S247
P
P
R
I
A
K
E
S
I
N
F
S
I
L
N
Site 17
S251
A
K
E
S
I
N
F
S
I
L
N
K
H
I
P
Site 18
S262
K
H
I
P
D
N
P
S
I
P
F
S
F
T
N
Site 19
S266
D
N
P
S
I
P
F
S
F
T
N
E
T
V
W
Site 20
T271
P
F
S
F
T
N
E
T
V
W
I
K
P
E
D
Site 21
Y283
P
E
D
Q
L
P
C
Y
L
T
H
T
N
P
R
Site 22
T285
D
Q
L
P
C
Y
L
T
H
T
N
P
R
V
D
Site 23
S303
L
K
N
L
H
L
N
S
H
V
K
E
T
T
R
Site 24
Y314
E
T
T
R
G
P
R
Y
C
P
S
I
E
S
K
Site 25
S317
R
G
P
R
Y
C
P
S
I
E
S
K
V
L
R
Site 26
S341
L
E
P
E
G
M
D
S
D
L
I
Y
P
Q
G
Site 27
Y345
G
M
D
S
D
L
I
Y
P
Q
G
L
S
M
T
Site 28
T363
E
L
Q
E
K
M
I
T
C
I
R
G
L
E
K
Site 29
Y403
H
N
L
P
L
P
G
Y
G
V
Q
Y
D
Y
L
Site 30
Y407
L
P
G
Y
G
V
Q
Y
D
Y
L
D
P
R
Q
Site 31
Y409
G
Y
G
V
Q
Y
D
Y
L
D
P
R
Q
I
T
Site 32
T416
Y
L
D
P
R
Q
I
T
P
S
L
E
T
H
L
Site 33
S418
D
P
R
Q
I
T
P
S
L
E
T
H
L
V
Q
Site 34
S466
R
K
P
P
F
V
V
S
R
T
E
G
Y
I
G
Site 35
Y471
V
V
S
R
T
E
G
Y
I
G
V
L
I
D
D
Site 36
T484
D
D
L
T
T
L
G
T
S
E
P
Y
R
M
F
Site 37
Y488
T
L
G
T
S
E
P
Y
R
M
F
T
S
R
V
Site 38
T492
S
E
P
Y
R
M
F
T
S
R
V
E
F
R
L
Site 39
S493
E
P
Y
R
M
F
T
S
R
V
E
F
R
L
S
Site 40
S500
S
R
V
E
F
R
L
S
L
R
P
D
N
A
D
Site 41
T511
D
N
A
D
S
R
L
T
L
R
G
Y
K
D
A
Site 42
Y515
S
R
L
T
L
R
G
Y
K
D
A
G
C
V
S
Site 43
S522
Y
K
D
A
G
C
V
S
Q
Q
R
Y
E
R
A
Site 44
S534
E
R
A
C
W
M
K
S
S
L
E
E
G
I
S
Site 45
S535
R
A
C
W
M
K
S
S
L
E
E
G
I
S
V
Site 46
S551
K
S
I
E
F
L
S
S
K
W
K
K
L
I
P
Site 47
S561
K
K
L
I
P
E
A
S
I
S
T
S
R
S
L
Site 48
T564
I
P
E
A
S
I
S
T
S
R
S
L
P
V
R
Site 49
S565
P
E
A
S
I
S
T
S
R
S
L
P
V
R
A
Site 50
S567
A
S
I
S
T
S
R
S
L
P
V
R
A
L
D
Site 51
Y578
R
A
L
D
V
L
K
Y
E
E
V
D
M
D
S
Site 52
S585
Y
E
E
V
D
M
D
S
L
A
K
A
V
P
E
Site 53
T598
P
E
P
L
K
K
Y
T
K
C
R
E
L
A
E
Site 54
T612
E
R
L
K
I
E
A
T
Y
E
S
V
L
F
H
Site 55
Y613
R
L
K
I
E
A
T
Y
E
S
V
L
F
H
Q
Site 56
Y641
Q
L
P
K
D
L
D
Y
L
T
I
R
D
V
S
Site 57
T643
P
K
D
L
D
Y
L
T
I
R
D
V
S
L
S
Site 58
S648
Y
L
T
I
R
D
V
S
L
S
H
E
V
R
E
Site 59
S650
T
I
R
D
V
S
L
S
H
E
V
R
E
K
L
Site 60
S660
V
R
E
K
L
H
F
S
R
P
Q
T
I
G
A
Site 61
T664
L
H
F
S
R
P
Q
T
I
G
A
A
S
R
I
Site 62
S669
P
Q
T
I
G
A
A
S
R
I
P
G
V
T
P
Site 63
T688
N
L
L
R
F
V
K
T
T
Q
R
R
Q
S
A
Site 64
T689
L
L
R
F
V
K
T
T
Q
R
R
Q
S
A
M
Site 65
S694
K
T
T
Q
R
R
Q
S
A
M
N
E
S
S
K
Site 66
S700
Q
S
A
M
N
E
S
S
K
T
D
Q
Y
L
C
Site 67
T702
A
M
N
E
S
S
K
T
D
Q
Y
L
C
D
A
Site 68
Y705
E
S
S
K
T
D
Q
Y
L
C
D
A
D
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation