PhosphoNET

           
Protein Info 
   
Short Name:  YARS2
Full Name:  Tyrosyl-tRNA synthetase, mitochondrial
Alias:  EC 6.1.1.1; SYYM; Tyrosine-tRNA ligase; TyrRS
Type:  Ligase
Mass (Da):  53199
Number AA:  477
UniProt ID:  Q9Y2Z4
International Prot ID:  IPI00165092
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005759     Uniprot OncoNet
Molecular Function:  GO:0005524  GO:0005515  GO:0004831 PhosphoSite+ KinaseNET
Biological Process:  GO:0006437     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S8MAAPILRSFSWGRWS
Site 2S10APILRSFSWGRWSGT
Site 3S15SFSWGRWSGTLNLSV
Site 4T69PELFDRGTASFPQTI
Site 5S71LFDRGTASFPQTIYC
Site 6T75GTASFPQTIYCGFDP
Site 7S123TARLGDPSGRTKERE
Site 8T134KEREALETERVRANA
Site 9T160ANHQQLFTDGRSWGS
Site 10S164QLFTDGRSWGSFTVL
Site 11S167TDGRSWGSFTVLDNS
Site 12T169GRSWGSFTVLDNSAW
Site 13T197GGHFRMGTLLSRQSV
Site 14S200FRMGTLLSRQSVQLR
Site 15S203GTLLSRQSVQLRLKS
Site 16S210SVQLRLKSPEGMSLA
Site 17S215LKSPEGMSLAEFFYQ
Site 18Y230VLQAYDFYYLFQRYG
Site 19Y231LQAYDFYYLFQRYGC
Site 20Y236FYYLFQRYGCRVQLG
Site 21T297VWLNRDKTSPFELYQ
Site 22S298WLNRDKTSPFELYQF
Site 23Y303KTSPFELYQFFVRQP
Site 24S313FVRQPDDSVERYLKL
Site 25Y317PDDSVERYLKLFTFL
Site 26S365HGREGLDSAKRCTQA
Site 27T370LDSAKRCTQALYHSS
Site 28Y374KRCTQALYHSSIDAL
Site 29T407EFFLDPGTSVLDTCR
Site 30S408FFLDPGTSVLDTCRK
Site 31T412PGTSVLDTCRKANAI
Site 32Y426IPDGPRGYRMITEGG
Site 33T430PRGYRMITEGGVSIN
Site 34S435MITEGGVSINHQQVT
Site 35S446QQVTNPESVLIVGQH
Site 36S460HILKNGLSLLKIGKR
Site 37Y470KIGKRNFYIIKWLQL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation