PhosphoNET

           
Protein Info 
   
Short Name:  KLK5
Full Name:  Kallikrein-5
Alias:  Kallikrein-like protein 2;Stratum corneum tryptic enzyme
Type: 
Mass (Da):  32019
Number AA:  293
UniProt ID:  Q9Y337
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S34VLANNDVSCDHPSNT
Site 2S39DVSCDHPSNTVPSGS
Site 3T41SCDHPSNTVPSGSNQ
Site 4S46SNTVPSGSNQDLGAG
Site 5S60GAGEDARSDDSSSRI
Site 6S63EDARSDDSSSRIING
Site 7S64DARSDDSSSRIINGS
Site 8S65ARSDDSSSRIINGSD
Site 9S71SSRIINGSDCDMHTQ
Site 10T77GSDCDMHTQPWQAAL
Site 11S122RVRLGHYSLSPVYES
Site 12S124RLGHYSLSPVYESGQ
Site 13Y127HYSLSPVYESGQQMF
Site 14S139QMFQGVKSIPHPGYS
Site 15Y145KSIPHPGYSHPGHSN
Site 16S146SIPHPGYSHPGHSND
Site 17T166LNRRIRPTKDVRPIN
Site 18S175DVRPINVSSHCPSAG
Site 19S176VRPINVSSHCPSAGT
Site 20S188AGTKCLVSGWGTTKS
Site 21T192CLVSGWGTTKSPQVH
Site 22T193LVSGWGTTKSPQVHF
Site 23S195SGWGTTKSPQVHFPK
Site 24S213CLNISVLSQKRCEDA
Site 25Y221QKRCEDAYPRQIDDT
Site 26S240GDKAGRDSCQGDSGG
Site 27Y264GLVSWGDYPCARPNR
Site 28T276PNRPGVYTNLCKFTK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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