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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC6A5
Full Name:
Sodium- and chloride-dependent glycine transporter 2
Alias:
GLYT2; GlyT-2; NET1; SC6A5; SLC6A5 solute carrier family 6 (neurotransmitter transporter, glycine), member 5; Sodium- and chloride-dependent glycine transporter 2; Solute carrier family 6 (neurotransmitter transporter, glycine), member 5; Solute carrier family 6 member 5
Type:
Transport protein, facilitator
Mass (Da):
87360
Number AA:
797
UniProt ID:
Q9Y345
International Prot ID:
IPI00003484
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0015375
GO:0005328
PhosphoSite+
KinaseNET
Biological Process:
GO:0006836
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
M
N
K
L
P
A
N
S
P
E
A
A
A
A
Q
Site 2
T34
D
G
P
C
A
P
R
T
S
P
E
Q
E
L
P
Site 3
S35
G
P
C
A
P
R
T
S
P
E
Q
E
L
P
A
Site 4
S54
P
P
P
R
V
P
R
S
A
S
T
G
A
Q
T
Site 5
S56
P
R
V
P
R
S
A
S
T
G
A
Q
T
F
Q
Site 6
T57
R
V
P
R
S
A
S
T
G
A
Q
T
F
Q
S
Site 7
T61
S
A
S
T
G
A
Q
T
F
Q
S
A
D
A
R
Site 8
S64
T
G
A
Q
T
F
Q
S
A
D
A
R
A
C
E
Site 9
S79
A
E
R
P
G
V
G
S
C
K
L
S
S
P
R
Site 10
S83
G
V
G
S
C
K
L
S
S
P
R
A
Q
A
A
Site 11
S84
V
G
S
C
K
L
S
S
P
R
A
Q
A
A
S
Site 12
S91
S
P
R
A
Q
A
A
S
A
A
L
R
D
L
R
Site 13
S106
E
A
Q
G
A
Q
A
S
P
P
P
G
S
S
G
Site 14
S111
Q
A
S
P
P
P
G
S
S
G
P
G
N
A
L
Site 15
S112
A
S
P
P
P
G
S
S
G
P
G
N
A
L
H
Site 16
S124
A
L
H
C
K
I
P
S
L
R
G
P
E
G
D
Site 17
S135
P
E
G
D
A
N
V
S
V
G
K
G
T
L
E
Site 18
T146
G
T
L
E
R
N
N
T
P
V
V
G
W
V
N
Site 19
S196
K
A
R
G
N
W
S
S
K
L
D
F
I
L
S
Site 20
Y219
G
N
V
W
R
F
P
Y
L
A
F
Q
N
G
G
Site 21
Y423
K
T
S
G
K
V
V
Y
F
T
A
T
F
P
Y
Site 22
T465
W
E
K
L
T
D
A
T
V
W
K
D
A
A
T
Site 23
S490
G
G
L
I
T
L
S
S
Y
N
K
F
H
N
N
Site 24
Y491
G
L
I
T
L
S
S
Y
N
K
F
H
N
N
C
Site 25
T506
Y
R
D
T
L
I
V
T
C
T
N
S
A
T
S
Site 26
Y550
P
G
I
A
F
V
V
Y
P
E
A
L
T
R
L
Site 27
S591
E
T
I
V
T
S
I
S
D
E
F
P
K
Y
L
Site 28
Y597
I
S
D
E
F
P
K
Y
L
R
T
H
K
P
V
Site 29
T600
E
F
P
K
Y
L
R
T
H
K
P
V
F
T
L
Site 30
Y705
Y
Q
W
E
P
M
T
Y
G
S
Y
R
Y
P
N
Site 31
Y708
E
P
M
T
Y
G
S
Y
R
Y
P
N
W
S
M
Site 32
Y710
M
T
Y
G
S
Y
R
Y
P
N
W
S
M
V
L
Site 33
S753
E
R
L
K
L
V
C
S
P
Q
P
D
W
G
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation