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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SH3GLB1
Full Name:
Endophilin-B1
Alias:
Bax-interacting factor 1; Bif-1; CGI-61; Endophilin B1; KIAA0491; SH3 domain GRB2-like B1; SH3 domain-containing GRB2-like protein B1; SH3-domain GRB2-like endophilin B1; SHLB1
Type:
Transferase; Apoptosis; EC 2.3.1.-
Mass (Da):
40796
Number AA:
365
UniProt ID:
Q9Y371
International Prot ID:
IPI00006558
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000139
GO:0005737
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008289
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006916
GO:0008219
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T26
L
S
R
A
V
Q
F
T
E
E
K
L
G
Q
A
Site 2
S47
A
H
L
E
N
L
L
S
K
A
E
C
T
K
I
Site 3
Y80
A
R
I
E
E
F
V
Y
E
K
L
D
R
K
A
Site 4
T106
Q
Y
M
I
D
A
G
T
E
F
G
P
G
T
A
Site 5
T130
E
T
Q
K
R
I
G
T
A
D
R
E
L
I
Q
Site 6
S139
D
R
E
L
I
Q
T
S
A
L
N
F
L
T
P
Site 7
Y155
R
N
F
I
E
G
D
Y
K
T
I
A
K
E
R
Site 8
T157
F
I
E
G
D
Y
K
T
I
A
K
E
R
K
L
Site 9
S190
K
A
A
E
T
R
N
S
S
E
Q
E
L
R
I
Site 10
S191
A
A
E
T
R
N
S
S
E
Q
E
L
R
I
T
Site 11
T198
S
E
Q
E
L
R
I
T
Q
S
E
F
D
R
Q
Site 12
S200
Q
E
L
R
I
T
Q
S
E
F
D
R
Q
A
E
Site 13
S217
R
L
L
L
E
G
I
S
S
T
H
A
H
H
L
Site 14
S218
L
L
L
E
G
I
S
S
T
H
A
H
H
L
R
Site 15
S254
D
L
Q
K
Q
L
G
S
F
P
S
N
Y
L
S
Site 16
S257
K
Q
L
G
S
F
P
S
N
Y
L
S
N
N
N
Site 17
Y259
L
G
S
F
P
S
N
Y
L
S
N
N
N
Q
T
Site 18
S261
S
F
P
S
N
Y
L
S
N
N
N
Q
T
S
V
Site 19
S267
L
S
N
N
N
Q
T
S
V
T
P
V
P
S
V
Site 20
T269
N
N
N
Q
T
S
V
T
P
V
P
S
V
L
P
Site 21
T293
S
T
S
G
L
V
I
T
S
P
S
N
L
S
D
Site 22
S296
G
L
V
I
T
S
P
S
N
L
S
D
L
K
E
Site 23
S299
I
T
S
P
S
N
L
S
D
L
K
E
C
S
G
Site 24
S305
L
S
D
L
K
E
C
S
G
S
R
K
A
R
V
Site 25
Y314
S
R
K
A
R
V
L
Y
D
Y
D
A
A
N
S
Site 26
Y316
K
A
R
V
L
Y
D
Y
D
A
A
N
S
T
E
Site 27
S321
Y
D
Y
D
A
A
N
S
T
E
L
S
L
L
A
Site 28
S342
F
S
V
V
G
M
D
S
D
W
L
M
G
E
R
Site 29
T359
Q
K
G
K
V
P
I
T
Y
L
E
L
L
N
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation