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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMED3
Full Name:
Transmembrane emp24 domain-containing protein 3
Alias:
Transmembrane emp24 protein transport domain containing 3
Type:
Membrane, ER-Golgi intermediate compartment membrane, Golgi apparatus, Integral membrane protein
Mass (Da):
24777
Number AA:
217
UniProt ID:
Q9Y3Q3
International Prot ID:
IPI00604599
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
G
S
T
V
P
R
S
A
S
V
Site 2
S8
M
G
S
T
V
P
R
S
A
S
V
L
L
L
L
Site 3
S10
S
T
V
P
R
S
A
S
V
L
L
L
L
L
L
Site 4
T30
Q
P
C
G
A
E
L
T
F
E
L
P
D
N
A
Site 5
Y55
G
V
K
F
S
L
D
Y
Q
V
I
T
G
G
H
Site 6
Y68
G
H
Y
D
V
D
C
Y
V
E
D
P
Q
G
N
Site 7
T81
G
N
T
I
Y
R
E
T
K
K
Q
Y
D
S
F
Site 8
S87
E
T
K
K
Q
Y
D
S
F
T
Y
R
A
E
V
Site 9
T89
K
K
Q
Y
D
S
F
T
Y
R
A
E
V
K
G
Site 10
Y98
R
A
E
V
K
G
V
Y
Q
F
C
F
S
N
E
Site 11
Y115
T
F
S
H
K
T
V
Y
F
D
F
Q
V
G
D
Site 12
T135
P
D
M
G
N
R
V
T
A
L
T
Q
M
E
S
Site 13
T146
Q
M
E
S
A
C
V
T
I
H
E
A
L
K
T
Site 14
T153
T
I
H
E
A
L
K
T
V
I
D
S
Q
T
H
Site 15
S157
A
L
K
T
V
I
D
S
Q
T
H
Y
R
L
R
Site 16
T159
K
T
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Site 17
Y161
V
I
D
S
Q
T
H
Y
R
L
R
E
A
Q
D
Site 18
S177
A
R
A
E
D
L
N
S
R
V
S
Y
W
S
V
Site 19
S180
E
D
L
N
S
R
V
S
Y
W
S
V
G
E
T
Site 20
Y181
D
L
N
S
R
V
S
Y
W
S
V
G
E
T
I
Site 21
S183
N
S
R
V
S
Y
W
S
V
G
E
T
I
A
L
Site 22
S203
S
Q
V
L
L
L
K
S
F
F
T
E
K
R
P
Site 23
T206
L
L
L
K
S
F
F
T
E
K
R
P
I
S
R
Site 24
S212
F
T
E
K
R
P
I
S
R
A
V
H
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation