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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
R3HCC1
Full Name:
R3H and coiled-coil domain-containing protein 1
Alias:
Type:
Mass (Da):
53259
Number AA:
480
UniProt ID:
Q9Y3T6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
M
K
A
S
R
V
T
L
G
E
A
G
A
R
Site 2
T23
R
A
R
W
P
L
G
T
P
R
A
A
A
T
R
Site 3
S76
F
L
L
Q
K
Q
L
S
K
V
L
L
F
P
P
Site 4
S85
V
L
L
F
P
P
L
S
S
R
L
R
Y
L
I
Site 5
S86
L
L
F
P
P
L
S
S
R
L
R
Y
L
I
H
Site 6
Y90
P
L
S
S
R
L
R
Y
L
I
H
R
T
A
E
Site 7
S103
A
E
N
F
D
L
L
S
S
F
S
V
G
E
G
Site 8
S104
E
N
F
D
L
L
S
S
F
S
V
G
E
G
W
Site 9
S106
F
D
L
L
S
S
F
S
V
G
E
G
W
K
R
Site 10
S126
H
Q
D
I
R
V
P
S
S
D
G
L
S
G
P
Site 11
S127
Q
D
I
R
V
P
S
S
D
G
L
S
G
P
C
Site 12
S131
V
P
S
S
D
G
L
S
G
P
C
R
A
P
A
Site 13
S139
G
P
C
R
A
P
A
S
C
P
S
R
Y
H
G
Site 14
S142
R
A
P
A
S
C
P
S
R
Y
H
G
P
R
P
Site 15
Y144
P
A
S
C
P
S
R
Y
H
G
P
R
P
I
S
Site 16
S151
Y
H
G
P
R
P
I
S
N
Q
G
A
A
A
V
Site 17
Y168
G
A
R
A
G
R
W
Y
R
G
R
K
P
D
Q
Site 18
Y178
R
K
P
D
Q
P
L
Y
V
P
R
V
L
R
R
Site 19
T192
R
Q
E
E
W
G
L
T
S
T
S
V
L
K
R
Site 20
S195
E
W
G
L
T
S
T
S
V
L
K
R
E
A
P
Site 21
S220
V
G
A
G
D
P
N
S
D
Q
G
L
P
V
L
Site 22
T229
Q
G
L
P
V
L
M
T
Q
G
T
E
D
L
K
Site 23
T232
P
V
L
M
T
Q
G
T
E
D
L
K
G
P
G
Site 24
S260
P
E
P
L
G
P
E
S
Q
S
G
K
G
D
M
Site 25
S276
E
M
A
T
R
F
G
S
T
L
Q
L
D
L
E
Site 26
T277
M
A
T
R
F
G
S
T
L
Q
L
D
L
E
K
Site 27
S311
E
V
E
E
D
G
P
S
S
C
S
E
D
D
Y
Site 28
S312
V
E
E
D
G
P
S
S
C
S
E
D
D
Y
S
Site 29
S314
E
D
G
P
S
S
C
S
E
D
D
Y
S
E
L
Site 30
Y318
S
S
C
S
E
D
D
Y
S
E
L
L
Q
E
I
Site 31
S319
S
C
S
E
D
D
Y
S
E
L
L
Q
E
I
T
Site 32
S344
E
K
I
H
L
D
T
S
S
F
V
E
E
L
P
Site 33
S345
K
I
H
L
D
T
S
S
F
V
E
E
L
P
G
Site 34
T377
K
T
E
D
L
L
A
T
F
S
E
F
Q
E
K
Site 35
S379
E
D
L
L
A
T
F
S
E
F
Q
E
K
G
F
Site 36
T423
V
L
K
I
R
P
L
T
Q
G
T
K
Q
S
K
Site 37
T449
L
V
K
E
R
P
Q
T
N
A
T
V
A
R
R
Site 38
T452
E
R
P
Q
T
N
A
T
V
A
R
R
L
V
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation