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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HBS1L
Full Name:
HBS1-like protein
Alias:
DKFZp434g247; EF-1a; ERFS; HBS1; HBS1-like; HSPC276; KIAA1038
Type:
Transcription factor
Mass (Da):
75473
Number AA:
684
UniProt ID:
Q9Y450
International Prot ID:
IPI00009070
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003746
PhosphoSite+
KinaseNET
Biological Process:
GO:0006412
GO:0007154
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
R
H
R
N
V
R
G
Y
N
Y
D
E
D
F
E
Site 2
Y12
R
N
V
R
G
Y
N
Y
D
E
D
F
E
D
D
Site 3
Y22
D
F
E
D
D
D
L
Y
G
Q
S
V
E
D
D
Site 4
Y30
G
Q
S
V
E
D
D
Y
C
I
S
P
S
T
A
Site 5
S33
V
E
D
D
Y
C
I
S
P
S
T
A
A
Q
F
Site 6
S35
D
D
Y
C
I
S
P
S
T
A
A
Q
F
I
Y
Site 7
T36
D
Y
C
I
S
P
S
T
A
A
Q
F
I
Y
S
Site 8
Y42
S
T
A
A
Q
F
I
Y
S
R
R
D
K
P
S
Site 9
S43
T
A
A
Q
F
I
Y
S
R
R
D
K
P
S
V
Site 10
S49
Y
S
R
R
D
K
P
S
V
E
P
V
E
E
Y
Site 11
Y56
S
V
E
P
V
E
E
Y
D
Y
E
D
L
K
E
Site 12
Y58
E
P
V
E
E
Y
D
Y
E
D
L
K
E
S
S
Site 13
S64
D
Y
E
D
L
K
E
S
S
N
S
V
S
N
H
Site 14
S65
Y
E
D
L
K
E
S
S
N
S
V
S
N
H
Q
Site 15
S67
D
L
K
E
S
S
N
S
V
S
N
H
Q
L
S
Site 16
S69
K
E
S
S
N
S
V
S
N
H
Q
L
S
G
F
Site 17
S74
S
V
S
N
H
Q
L
S
G
F
D
Q
A
R
L
Site 18
Y82
G
F
D
Q
A
R
L
Y
S
C
L
D
H
M
R
Site 19
S117
F
D
V
Q
K
A
L
S
G
V
L
E
Q
D
R
Site 20
S127
L
E
Q
D
R
V
Q
S
L
K
D
K
N
E
A
Site 21
T135
L
K
D
K
N
E
A
T
V
S
T
G
K
I
A
Site 22
S149
A
K
G
K
P
V
D
S
Q
T
S
R
S
E
S
Site 23
T151
G
K
P
V
D
S
Q
T
S
R
S
E
S
E
I
Site 24
S152
K
P
V
D
S
Q
T
S
R
S
E
S
E
I
V
Site 25
S154
V
D
S
Q
T
S
R
S
E
S
E
I
V
P
K
Site 26
S156
S
Q
T
S
R
S
E
S
E
I
V
P
K
V
A
Site 27
S182
G
F
E
V
P
G
V
S
S
E
E
N
G
H
S
Site 28
S183
F
E
V
P
G
V
S
S
E
E
N
G
H
S
F
Site 29
S189
S
S
E
E
N
G
H
S
F
H
T
P
Q
K
G
Site 30
T192
E
N
G
H
S
F
H
T
P
Q
K
G
P
P
I
Site 31
T211
A
S
S
D
V
L
E
T
A
S
K
S
A
N
P
Site 32
S213
S
D
V
L
E
T
A
S
K
S
A
N
P
P
H
Site 33
S215
V
L
E
T
A
S
K
S
A
N
P
P
H
T
I
Site 34
T221
K
S
A
N
P
P
H
T
I
Q
A
S
E
E
Q
Site 35
S225
P
P
H
T
I
Q
A
S
E
E
Q
S
S
T
P
Site 36
S229
I
Q
A
S
E
E
Q
S
S
T
P
A
P
V
K
Site 37
S230
Q
A
S
E
E
Q
S
S
T
P
A
P
V
K
K
Site 38
T231
A
S
E
E
Q
S
S
T
P
A
P
V
K
K
S
Site 39
S274
G
H
V
D
A
G
K
S
T
L
M
G
H
M
L
Site 40
Y295
N
K
R
T
M
H
K
Y
E
Q
E
S
K
K
A
Site 41
S306
S
K
K
A
G
K
A
S
F
A
Y
A
W
V
L
Site 42
Y309
A
G
K
A
S
F
A
Y
A
W
V
L
D
E
T
Site 43
T325
E
E
R
E
R
G
V
T
M
D
V
G
M
T
K
Site 44
T341
E
T
T
T
K
V
I
T
L
M
D
A
P
G
H
Site 45
T422
Q
E
R
F
Q
E
I
T
G
K
L
G
H
F
L
Site 46
S437
K
Q
A
G
F
K
E
S
D
V
G
F
I
P
T
Site 47
T454
L
S
G
E
N
L
I
T
R
S
Q
S
S
E
L
Site 48
S456
G
E
N
L
I
T
R
S
Q
S
S
E
L
T
K
Site 49
S458
N
L
I
T
R
S
Q
S
S
E
L
T
K
W
Y
Site 50
T462
R
S
Q
S
S
E
L
T
K
W
Y
K
G
L
C
Site 51
Y465
S
S
E
L
T
K
W
Y
K
G
L
C
L
L
E
Site 52
S476
C
L
L
E
Q
I
D
S
F
K
P
P
Q
R
S
Site 53
S483
S
F
K
P
P
Q
R
S
I
D
K
P
F
R
L
Site 54
S493
K
P
F
R
L
C
V
S
D
V
F
K
D
Q
G
Site 55
S501
D
V
F
K
D
Q
G
S
G
F
C
I
T
G
K
Site 56
Y513
T
G
K
I
E
A
G
Y
I
Q
T
G
D
R
L
Site 57
T516
I
E
A
G
Y
I
Q
T
G
D
R
L
L
A
M
Site 58
T528
L
A
M
P
P
N
E
T
C
T
V
K
G
I
T
Site 59
T530
M
P
P
N
E
T
C
T
V
K
G
I
T
L
H
Site 60
Y604
G
F
P
V
L
L
H
Y
Q
T
V
S
E
P
A
Site 61
S623
L
I
S
V
L
N
K
S
T
G
E
V
T
K
K
Site 62
T647
N
A
L
V
E
L
Q
T
Q
R
P
I
A
L
E
Site 63
Y656
R
P
I
A
L
E
L
Y
K
D
F
K
E
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation