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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBX22
Full Name:
T-box transcription factor TBX22
Alias:
Type:
Mass (Da):
57910
Number AA:
520
UniProt ID:
Q9Y458
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
S
R
A
R
A
F
S
V
E
A
L
V
G
R
Site 2
S20
E
A
L
V
G
R
P
S
K
R
K
L
Q
D
P
Site 3
S49
E
E
E
E
E
R
R
S
S
A
A
G
K
S
E
Site 4
S50
E
E
E
E
R
R
S
S
A
A
G
K
S
E
P
Site 5
S55
R
S
S
A
A
G
K
S
E
P
L
E
K
Q
P
Site 6
T64
P
L
E
K
Q
P
K
T
E
P
S
T
S
A
S
Site 7
S67
K
Q
P
K
T
E
P
S
T
S
A
S
S
G
C
Site 8
T68
Q
P
K
T
E
P
S
T
S
A
S
S
G
C
G
Site 9
S69
P
K
T
E
P
S
T
S
A
S
S
G
C
G
S
Site 10
S71
T
E
P
S
T
S
A
S
S
G
C
G
S
D
S
Site 11
S72
E
P
S
T
S
A
S
S
G
C
G
S
D
S
G
Site 12
S76
S
A
S
S
G
C
G
S
D
S
G
Y
G
N
S
Site 13
S78
S
S
G
C
G
S
D
S
G
Y
G
N
S
S
E
Site 14
Y80
G
C
G
S
D
S
G
Y
G
N
S
S
E
S
L
Site 15
S83
S
D
S
G
Y
G
N
S
S
E
S
L
E
E
K
Site 16
S84
D
S
G
Y
G
N
S
S
E
S
L
E
E
K
D
Site 17
S86
G
Y
G
N
S
S
E
S
L
E
E
K
D
I
Q
Site 18
T110
K
R
F
H
D
I
G
T
E
M
I
I
T
K
A
Site 19
S124
A
G
R
R
M
F
P
S
V
R
V
K
V
K
G
Site 20
Y138
G
L
D
P
G
K
Q
Y
H
V
A
I
D
V
V
Site 21
Y154
V
D
S
K
R
Y
R
Y
V
Y
H
S
S
Q
W
Site 22
Y156
S
K
R
Y
R
Y
V
Y
H
S
S
Q
W
M
V
Site 23
S182
R
F
Y
V
H
P
D
S
P
C
S
G
E
T
W
Site 24
Y220
I
L
Q
S
M
H
K
Y
K
P
R
V
H
V
I
Site 25
S232
H
V
I
E
Q
G
S
S
V
D
L
S
Q
I
Q
Site 26
S236
Q
G
S
S
V
D
L
S
Q
I
Q
S
L
P
T
Site 27
S240
V
D
L
S
Q
I
Q
S
L
P
T
E
G
V
K
Site 28
T243
S
Q
I
Q
S
L
P
T
E
G
V
K
T
F
S
Site 29
T248
L
P
T
E
G
V
K
T
F
S
F
K
E
T
E
Site 30
S250
T
E
G
V
K
T
F
S
F
K
E
T
E
F
T
Site 31
T254
K
T
F
S
F
K
E
T
E
F
T
T
V
T
A
Site 32
T257
S
F
K
E
T
E
F
T
T
V
T
A
Y
Q
N
Site 33
Y262
E
F
T
T
V
T
A
Y
Q
N
Q
Q
I
T
K
Site 34
T284
F
A
K
G
F
R
D
T
G
R
N
R
G
V
L
Site 35
T297
V
L
D
G
L
L
E
T
Y
P
W
R
P
S
F
Site 36
Y298
L
D
G
L
L
E
T
Y
P
W
R
P
S
F
T
Site 37
S303
E
T
Y
P
W
R
P
S
F
T
L
D
F
K
T
Site 38
T310
S
F
T
L
D
F
K
T
F
G
A
D
T
Q
S
Site 39
T315
F
K
T
F
G
A
D
T
Q
S
G
S
S
G
S
Site 40
S317
T
F
G
A
D
T
Q
S
G
S
S
G
S
S
P
Site 41
S319
G
A
D
T
Q
S
G
S
S
G
S
S
P
V
T
Site 42
S322
T
Q
S
G
S
S
G
S
S
P
V
T
S
S
G
Site 43
S323
Q
S
G
S
S
G
S
S
P
V
T
S
S
G
G
Site 44
T326
S
S
G
S
S
P
V
T
S
S
G
G
A
P
S
Site 45
S327
S
G
S
S
P
V
T
S
S
G
G
A
P
S
P
Site 46
S328
G
S
S
P
V
T
S
S
G
G
A
P
S
P
L
Site 47
S333
T
S
S
G
G
A
P
S
P
L
N
S
L
L
S
Site 48
S396
P
A
P
E
R
L
A
S
S
N
S
S
Q
S
L
Site 49
S397
A
P
E
R
L
A
S
S
N
S
S
Q
S
L
A
Site 50
S399
E
R
L
A
S
S
N
S
S
Q
S
L
A
P
L
Site 51
S400
R
L
A
S
S
N
S
S
Q
S
L
A
P
L
M
Site 52
S402
A
S
S
N
S
S
Q
S
L
A
P
L
M
M
E
Site 53
T419
M
L
S
S
L
G
V
T
N
S
K
S
G
S
S
Site 54
S421
S
S
L
G
V
T
N
S
K
S
G
S
S
E
D
Site 55
S423
L
G
V
T
N
S
K
S
G
S
S
E
D
S
S
Site 56
S425
V
T
N
S
K
S
G
S
S
E
D
S
S
D
Q
Site 57
S426
T
N
S
K
S
G
S
S
E
D
S
S
D
Q
Y
Site 58
S429
K
S
G
S
S
E
D
S
S
D
Q
Y
L
Q
A
Site 59
S430
S
G
S
S
E
D
S
S
D
Q
Y
L
Q
A
P
Site 60
Y433
S
E
D
S
S
D
Q
Y
L
Q
A
P
N
S
T
Site 61
Y445
N
S
T
N
Q
M
L
Y
G
L
Q
S
P
G
N
Site 62
S465
S
I
T
P
E
A
L
S
C
S
F
H
P
S
Y
Site 63
S467
T
P
E
A
L
S
C
S
F
H
P
S
Y
D
F
Site 64
Y472
S
C
S
F
H
P
S
Y
D
F
Y
R
Y
N
F
Site 65
Y475
F
H
P
S
Y
D
F
Y
R
Y
N
F
S
M
P
Site 66
Y477
P
S
Y
D
F
Y
R
Y
N
F
S
M
P
S
R
Site 67
S480
D
F
Y
R
Y
N
F
S
M
P
S
R
L
I
S
Site 68
S483
R
Y
N
F
S
M
P
S
R
L
I
S
G
S
N
Site 69
S487
S
M
P
S
R
L
I
S
G
S
N
H
L
K
V
Site 70
S489
P
S
R
L
I
S
G
S
N
H
L
K
V
N
D
Site 71
S498
H
L
K
V
N
D
D
S
Q
V
S
F
G
E
G
Site 72
S501
V
N
D
D
S
Q
V
S
F
G
E
G
K
C
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation