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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
L3MBTL
Full Name:
Lethal(3)malignant brain tumor-like protein
Alias:
L(3)mbt protein homolog;L3MBTL1
Type:
Mass (Da):
85917
Number AA:
772
UniProt ID:
Q9Y468
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
R
R
R
E
G
H
G
T
D
S
E
M
G
Q
G
Site 2
S11
R
E
G
H
G
T
D
S
E
M
G
Q
G
P
V
Site 3
S21
G
Q
G
P
V
R
E
S
Q
S
S
D
P
P
A
Site 4
S24
P
V
R
E
S
Q
S
S
D
P
P
A
L
Q
F
Site 5
S34
P
A
L
Q
F
R
I
S
E
Y
K
P
L
N
M
Site 6
S49
A
G
V
E
Q
P
P
S
P
E
L
R
Q
E
G
Site 7
T58
E
L
R
Q
E
G
V
T
E
Y
E
D
G
G
A
Site 8
Y60
R
Q
E
G
V
T
E
Y
E
D
G
G
A
P
A
Site 9
S116
A
A
G
P
D
L
G
S
S
N
D
G
C
P
Q
Site 10
S117
A
G
P
D
L
G
S
S
N
D
G
C
P
Q
L
Site 11
S129
P
Q
L
F
Q
E
R
S
V
I
V
E
N
S
S
Site 12
S135
R
S
V
I
V
E
N
S
S
G
S
T
S
A
S
Site 13
S136
S
V
I
V
E
N
S
S
G
S
T
S
A
S
E
Site 14
S138
I
V
E
N
S
S
G
S
T
S
A
S
E
L
L
Site 15
S140
E
N
S
S
G
S
T
S
A
S
E
L
L
K
P
Site 16
S142
S
S
G
S
T
S
A
S
E
L
L
K
P
M
K
Site 17
Y156
K
K
R
K
R
R
E
Y
Q
S
P
S
E
E
E
Site 18
S158
R
K
R
R
E
Y
Q
S
P
S
E
E
E
S
E
Site 19
S160
R
R
E
Y
Q
S
P
S
E
E
E
S
E
P
E
Site 20
S164
Q
S
P
S
E
E
E
S
E
P
E
A
M
E
K
Site 21
T183
K
D
P
E
G
Q
P
T
A
S
T
P
E
S
E
Site 22
S185
P
E
G
Q
P
T
A
S
T
P
E
S
E
E
W
Site 23
T186
E
G
Q
P
T
A
S
T
P
E
S
E
E
W
S
Site 24
S189
P
T
A
S
T
P
E
S
E
E
W
S
S
S
Q
Site 25
S193
T
P
E
S
E
E
W
S
S
S
Q
P
A
T
G
Site 26
S194
P
E
S
E
E
W
S
S
S
Q
P
A
T
G
E
Site 27
S195
E
S
E
E
W
S
S
S
Q
P
A
T
G
E
K
Site 28
T199
W
S
S
S
Q
P
A
T
G
E
K
K
E
C
W
Site 29
Y211
E
C
W
S
W
E
S
Y
L
E
E
Q
K
A
I
Site 30
S228
P
V
S
L
F
Q
D
S
Q
A
V
T
H
N
K
Site 31
T232
F
Q
D
S
Q
A
V
T
H
N
K
N
G
F
K
Site 32
Y255
D
P
Q
H
P
S
M
Y
F
I
L
T
V
A
E
Site 33
Y275
L
R
L
H
F
D
G
Y
S
E
C
H
D
F
W
Site 34
S287
D
F
W
V
N
A
N
S
P
D
I
H
P
A
G
Site 35
T299
P
A
G
W
F
E
K
T
G
H
K
L
Q
P
P
Site 36
S315
G
Y
K
E
E
E
F
S
W
S
Q
Y
L
R
S
Site 37
S317
K
E
E
E
F
S
W
S
Q
Y
L
R
S
T
R
Site 38
Y319
E
E
F
S
W
S
Q
Y
L
R
S
T
R
A
Q
Site 39
S322
S
W
S
Q
Y
L
R
S
T
R
A
Q
A
A
P
Site 40
T323
W
S
Q
Y
L
R
S
T
R
A
Q
A
A
P
K
Site 41
S335
A
P
K
H
L
F
V
S
Q
S
H
S
P
P
P
Site 42
S337
K
H
L
F
V
S
Q
S
H
S
P
P
P
L
G
Site 43
S339
L
F
V
S
Q
S
H
S
P
P
P
L
G
F
Q
Site 44
T411
Q
K
Q
G
K
P
L
T
P
P
Q
D
Y
P
D
Site 45
Y416
P
L
T
P
P
Q
D
Y
P
D
P
D
N
F
C
Site 46
Y427
D
N
F
C
W
E
K
Y
L
E
E
T
G
A
S
Site 47
S448
F
K
V
R
P
P
H
S
F
L
V
N
M
K
L
Site 48
S470
P
A
L
I
R
V
A
S
V
E
D
V
E
D
H
Site 49
T510
P
A
G
W
C
S
K
T
G
H
P
L
Q
P
P
Site 50
S524
P
L
G
P
R
E
P
S
S
A
S
P
G
G
C
Site 51
S525
L
G
P
R
E
P
S
S
A
S
P
G
G
C
P
Site 52
S527
P
R
E
P
S
S
A
S
P
G
G
C
P
P
L
Site 53
S535
P
G
G
C
P
P
L
S
Y
R
S
L
P
H
T
Site 54
Y536
G
G
C
P
P
L
S
Y
R
S
L
P
H
T
R
Site 55
S538
C
P
P
L
S
Y
R
S
L
P
H
T
R
T
S
Site 56
T542
S
Y
R
S
L
P
H
T
R
T
S
K
Y
S
F
Site 57
T544
R
S
L
P
H
T
R
T
S
K
Y
S
F
H
H
Site 58
S545
S
L
P
H
T
R
T
S
K
Y
S
F
H
H
R
Site 59
Y547
P
H
T
R
T
S
K
Y
S
F
H
H
R
K
C
Site 60
T556
F
H
H
R
K
C
P
T
P
G
C
D
G
S
G
Site 61
S562
P
T
P
G
C
D
G
S
G
H
V
T
G
K
F
Site 62
S576
F
T
A
H
H
C
L
S
G
C
P
L
A
E
R
Site 63
S586
P
L
A
E
R
N
Q
S
R
L
K
A
E
L
S
Site 64
S593
S
R
L
K
A
E
L
S
D
S
E
A
S
A
R
Site 65
S595
L
K
A
E
L
S
D
S
E
A
S
A
R
K
K
Site 66
S598
E
L
S
D
S
E
A
S
A
R
K
K
N
L
S
Site 67
S605
S
A
R
K
K
N
L
S
G
F
S
P
R
K
K
Site 68
S608
K
K
N
L
S
G
F
S
P
R
K
K
P
R
H
Site 69
Y625
R
I
G
R
P
P
K
Y
R
K
I
P
Q
E
D
Site 70
T635
I
P
Q
E
D
F
Q
T
L
T
P
D
V
V
H
Site 71
T637
Q
E
D
F
Q
T
L
T
P
D
V
V
H
Q
S
Site 72
S648
V
H
Q
S
L
F
M
S
A
L
S
A
H
P
D
Site 73
S651
S
L
F
M
S
A
L
S
A
H
P
D
R
S
L
Site 74
S657
L
S
A
H
P
D
R
S
L
S
V
C
W
E
Q
Site 75
T696
F
G
F
V
Q
T
L
T
G
C
E
D
Q
A
R
Site 76
T715
E
A
R
I
V
R
V
T
H
V
S
G
K
T
L
Site 77
S735
Q
L
G
D
L
V
C
S
D
H
L
Q
E
G
K
Site 78
S765
T
H
L
L
A
K
L
S
F
A
S
D
S
Q
Y
Site 79
S768
L
A
K
L
S
F
A
S
D
S
Q
Y
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation