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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTF2
Full Name:
Metal-response element-binding transcription factor 2
Alias:
M96; Metal regulatory transcription factor 2; Metal response element binding transcription factor 2; Metal-response element DNA-binding M96; PCL2; Polycomb-like 2
Type:
Mass (Da):
67090
Number AA:
UniProt ID:
Q9Y483
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
R
D
S
T
G
A
G
N
S
L
V
Site 2
S10
D
S
T
G
A
G
N
S
L
V
H
K
R
S
P
Site 3
S16
N
S
L
V
H
K
R
S
P
L
R
R
N
Q
K
Site 4
T24
P
L
R
R
N
Q
K
T
P
T
S
L
T
K
L
Site 5
S27
R
N
Q
K
T
P
T
S
L
T
K
L
S
L
Q
Site 6
T29
Q
K
T
P
T
S
L
T
K
L
S
L
Q
D
G
Site 7
S32
P
T
S
L
T
K
L
S
L
Q
D
G
H
K
A
Site 8
T95
V
L
W
K
D
I
Q
T
G
A
T
G
S
G
E
Site 9
T106
G
S
G
E
M
V
C
T
I
C
Q
E
E
Y
S
Site 10
T135
G
Y
H
Q
L
C
H
T
P
H
I
D
S
S
V
Site 11
S141
H
T
P
H
I
D
S
S
V
I
D
S
D
E
K
Site 12
S145
I
D
S
S
V
I
D
S
D
E
K
W
L
C
R
Site 13
T160
Q
C
V
F
A
T
T
T
K
R
G
G
A
L
K
Site 14
S185
M
K
Q
T
L
P
Y
S
V
A
D
L
E
W
D
Site 15
Y245
M
L
F
G
D
R
F
Y
T
F
I
C
S
V
C
Site 16
S254
F
I
C
S
V
C
S
S
G
P
E
Y
L
K
R
Site 17
Y258
V
C
S
S
G
P
E
Y
L
K
R
L
P
L
Q
Site 18
Y285
S
V
I
H
K
K
K
Y
F
D
S
E
L
E
L
Site 19
S288
H
K
K
K
Y
F
D
S
E
L
E
L
M
T
Y
Site 20
Y295
S
E
L
E
L
M
T
Y
I
N
E
N
W
D
R
Site 21
T311
H
P
G
E
L
A
D
T
P
K
S
E
R
Y
E
Site 22
S314
E
L
A
D
T
P
K
S
E
R
Y
E
H
V
L
Site 23
Y327
V
L
E
A
L
N
D
Y
K
T
M
F
M
S
G
Site 24
T329
E
A
L
N
D
Y
K
T
M
F
M
S
G
K
E
Site 25
T368
A
E
K
E
P
E
G
T
S
H
E
F
K
I
K
Site 26
S380
K
I
K
G
R
K
A
S
K
P
I
S
D
S
R
Site 27
S384
R
K
A
S
K
P
I
S
D
S
R
E
V
S
N
Site 28
S386
A
S
K
P
I
S
D
S
R
E
V
S
N
G
I
Site 29
S390
I
S
D
S
R
E
V
S
N
G
I
E
K
K
G
Site 30
S401
E
K
K
G
K
K
K
S
V
G
R
P
P
G
P
Site 31
Y409
V
G
R
P
P
G
P
Y
T
R
K
M
I
Q
K
Site 32
T410
G
R
P
P
G
P
Y
T
R
K
M
I
Q
K
T
Site 33
T417
T
R
K
M
I
Q
K
T
A
E
P
L
L
D
K
Site 34
S426
E
P
L
L
D
K
E
S
I
S
E
N
P
T
L
Site 35
S428
L
L
D
K
E
S
I
S
E
N
P
T
L
D
L
Site 36
T432
E
S
I
S
E
N
P
T
L
D
L
P
C
S
I
Site 37
S438
P
T
L
D
L
P
C
S
I
G
R
T
E
G
T
Site 38
T442
L
P
C
S
I
G
R
T
E
G
T
A
H
S
S
Site 39
T445
S
I
G
R
T
E
G
T
A
H
S
S
N
T
S
Site 40
S448
R
T
E
G
T
A
H
S
S
N
T
S
D
V
D
Site 41
S452
T
A
H
S
S
N
T
S
D
V
D
F
T
G
A
Site 42
T465
G
A
S
S
A
K
E
T
T
S
S
S
I
S
R
Site 43
S467
S
S
A
K
E
T
T
S
S
S
I
S
R
H
Y
Site 44
S468
S
A
K
E
T
T
S
S
S
I
S
R
H
Y
G
Site 45
S469
A
K
E
T
T
S
S
S
I
S
R
H
Y
G
L
Site 46
S471
E
T
T
S
S
S
I
S
R
H
Y
G
L
S
D
Site 47
Y474
S
S
S
I
S
R
H
Y
G
L
S
D
S
R
K
Site 48
S477
I
S
R
H
Y
G
L
S
D
S
R
K
R
T
R
Site 49
S479
R
H
Y
G
L
S
D
S
R
K
R
T
R
T
G
Site 50
T483
L
S
D
S
R
K
R
T
R
T
G
R
S
W
P
Site 51
T485
D
S
R
K
R
T
R
T
G
R
S
W
P
A
A
Site 52
S488
K
R
T
R
T
G
R
S
W
P
A
A
I
P
H
Site 53
T510
L
P
R
R
A
L
Q
T
Q
N
S
E
I
V
K
Site 54
S513
R
A
L
Q
T
Q
N
S
E
I
V
K
D
D
E
Site 55
Y525
D
D
E
G
K
E
D
Y
Q
F
D
E
L
N
T
Site 56
Y568
R
I
A
C
G
E
K
Y
R
V
L
A
R
R
V
Site 57
T576
R
V
L
A
R
R
V
T
L
D
G
K
V
Q
Y
Site 58
Y583
T
L
D
G
K
V
Q
Y
L
V
E
W
E
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation