PhosphoNET

           
Protein Info 
   
Short Name:  TJ6
Full Name:  V-type proton ATPase 116 kDa subunit a isoform 2
Alias:  A2; ATP6a2; ATP6N1D; ATP6V0A2; ATPase, H+ transporting, lysosomal V0 subunit a2; Infantile malignant osteopetrosis; J6B7; Stv1; TJ6M; TJ6s; V- ATPase 116-kDa isoform a2; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2; Vph1; VPP2
Type:  Transporter; Energy Metabolism - oxidative phosphorylation
Mass (Da):  98082
Number AA:  856
UniProt ID:  Q9Y487
International Prot ID:  IPI00000425
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0010008  GO:0016021  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0015078  GO:0005515   PhosphoSite+ KinaseNET
Biological Process:  GO:0015986  GO:0006955   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S45RDLNQNVSSFQRKFV
Site 2S46DLNQNVSSFQRKFVG
Site 3S85PLPEGEASPPAPPLK
Site 4T112EVELREVTKNKEKLR
Site 5Y128NLLELIEYTHMLRVT
Site 6T129LLELIEYTHMLRVTK
Site 7T135YTHMLRVTKTFVKRN
Site 8T137HMLRVTKTFVKRNVE
Site 9T148RNVEFEPTYEEFPSL
Site 10Y149NVEFEPTYEEFPSLE
Site 11S154PTYEEFPSLESDSLL
Site 12S157EEFPSLESDSLLDYS
Site 13S159FPSLESDSLLDYSCM
Site 14Y163ESDSLLDYSCMQRLG
Site 15S164SDSLLDYSCMQRLGA
Site 16S177GAKLGFVSGLINQGK
Site 17Y204KGYTIVSYAELDESL
Site 18S210SYAELDESLEDPETG
Site 19T216ESLEDPETGEVIKWY
Site 20Y223TGEVIKWYVFLISFW
Site 21Y252YHCHVYPYPNTAEER
Site 22T268EIQEGLNTRIQDLYT
Site 23Y274NTRIQDLYTVLHKTE
Site 24T275TRIQDLYTVLHKTED
Site 25Y283VLHKTEDYLRQVLCK
Site 26Y296CKAAESVYSRVIQVK
Site 27S297KAAESVYSRVIQVKK
Site 28S349LEEGSRESGATIPSF
Site 29T352GSRESGATIPSFMNI
Site 30T365NIIPTKETPPTRIRT
Site 31T368PTKETPPTRIRTNKF
Site 32T372TPPTRIRTNKFTEGF
Site 33T376RIRTNKFTEGFQNIV
Site 34Y386FQNIVDAYGVGSYRE
Site 35S390VDAYGVGSYREVNPA
Site 36Y468SVYTGLIYNDCFSKS
Site 37S486FGSGWNVSAMYSSSH
Site 38Y489GWNVSAMYSSSHPPA
Site 39S490WNVSAMYSSSHPPAE
Site 40S491NVSAMYSSSHPPAEH
Site 41S492VSAMYSSSHPPAEHK
Site 42S513DSVVRHNSILQLDPS
Site 43T545NLATNRLTFLNSFKM
Site 44S549NRLTFLNSFKMKMSV
Site 45T643SKTSGLYTGQEYVQR
Site 46S686SCFGVNRSGYTLIRK
Site 47Y688FGVNRSGYTLIRKDS
Site 48S695YTLIRKDSEEEVSLL
Site 49S700KDSEEEVSLLGSQDI
Site 50S704EEVSLLGSQDIEEGN
Site 51Y830VEFQNKFYVGAGTKF
Site 52S846PFSFSLLSSKFNNDD
Site 53S847FSFSLLSSKFNNDDS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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