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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
JRKL
Full Name:
Jerky protein homolog-like
Alias:
HHMJG; JERKL
Type:
Nucleus protein
Mass (Da):
50710
Number AA:
442
UniProt ID:
Q9Y4A0
International Prot ID:
IPI00216634
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0007417
GO:0045449
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
K
K
L
E
D
G
G
S
S
K
Q
L
A
V
I
Site 2
T41
I
Y
G
I
G
E
T
T
V
R
D
I
R
K
N
Site 3
T54
K
N
K
E
K
I
I
T
Y
A
S
S
S
D
S
Site 4
Y55
N
K
E
K
I
I
T
Y
A
S
S
S
D
S
T
Site 5
S57
E
K
I
I
T
Y
A
S
S
S
D
S
T
S
L
Site 6
S58
K
I
I
T
Y
A
S
S
S
D
S
T
S
L
L
Site 7
S61
T
Y
A
S
S
S
D
S
T
S
L
L
A
K
R
Site 8
S63
A
S
S
S
D
S
T
S
L
L
A
K
R
K
S
Site 9
S70
S
L
L
A
K
R
K
S
M
K
P
S
M
Y
E
Site 10
S74
K
R
K
S
M
K
P
S
M
Y
E
E
L
D
R
Site 11
S98
R
A
K
G
N
P
I
S
G
P
I
C
A
K
R
Site 12
Y111
K
R
A
E
F
F
F
Y
A
L
G
M
D
G
D
Site 13
S134
T
R
F
K
Q
R
H
S
I
R
E
I
N
I
R
Site 14
T150
E
R
L
N
G
D
E
T
A
V
E
D
F
C
N
Site 15
Y174
N
L
Q
P
E
Q
I
Y
N
A
D
E
T
G
L
Site 16
S191
K
C
L
P
S
R
I
S
V
I
K
G
K
C
T
Site 17
T198
S
V
I
K
G
K
C
T
V
P
G
H
K
S
I
Site 18
S204
C
T
V
P
G
H
K
S
I
E
E
R
V
T
I
Site 19
S236
G
K
A
K
K
P
R
S
F
K
S
T
D
T
L
Site 20
S239
K
K
P
R
S
F
K
S
T
D
T
L
N
L
P
Site 21
T240
K
P
R
S
F
K
S
T
D
T
L
N
L
P
V
Site 22
T242
R
S
F
K
S
T
D
T
L
N
L
P
V
S
Y
Site 23
S248
D
T
L
N
L
P
V
S
Y
F
S
Q
K
G
A
Site 24
Y249
T
L
N
L
P
V
S
Y
F
S
Q
K
G
A
W
Site 25
Y277
F
V
P
Q
V
R
E
Y
L
R
S
K
G
L
Q
Site 26
S280
Q
V
R
E
Y
L
R
S
K
G
L
Q
E
K
A
Site 27
S294
A
V
L
L
L
D
N
S
P
T
H
P
N
E
N
Site 28
S305
P
N
E
N
V
L
R
S
D
D
G
Q
I
F
A
Site 29
Y314
D
G
Q
I
F
A
K
Y
L
P
P
N
V
A
S
Site 30
Y338
I
A
T
M
K
R
N
Y
R
A
G
L
L
Q
N
Site 31
S355
E
E
G
N
D
L
K
S
F
W
K
K
L
T
L
Site 32
T361
K
S
F
W
K
K
L
T
L
L
D
A
L
Y
E
Site 33
T380
W
N
L
V
K
P
V
T
I
S
R
A
W
K
K
Site 34
S397
P
M
V
E
E
K
E
S
L
D
F
D
V
E
D
Site 35
T425
K
G
L
E
N
V
T
T
E
N
L
E
K
W
L
Site 36
S436
E
K
W
L
E
V
D
S
T
E
P
G
Y
E
V
Site 37
T437
K
W
L
E
V
D
S
T
E
P
G
Y
E
V
L
Site 38
Y441
V
D
S
T
E
P
G
Y
E
V
L
T
D
S
E
Site 39
T445
E
P
G
Y
E
V
L
T
D
S
E
I
I
R
R
Site 40
S447
G
Y
E
V
L
T
D
S
E
I
I
R
R
A
Q
Site 41
S460
A
Q
G
Q
A
D
E
S
S
E
N
E
E
E
E
Site 42
S461
Q
G
Q
A
D
E
S
S
E
N
E
E
E
E
I
Site 43
Y491
W
T
E
N
L
L
D
Y
L
E
Q
Q
G
D
M
Site 44
T512
V
I
R
K
L
R
A
T
I
R
N
K
Q
K
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation