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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NFE2L3
Full Name:
Nuclear factor erythroid 2-related factor 3
Alias:
NRF3
Type:
Nucleus protein
Mass (Da):
76154
Number AA:
694
UniProt ID:
Q9Y4A8
International Prot ID:
IPI00009207
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0046983
GO:0043565
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
H
L
K
R
W
W
S
A
G
G
G
L
L
H
Site 2
S63
A
Y
A
L
S
P
F
S
A
S
G
G
W
G
R
Site 3
S142
S
T
G
G
A
G
A
S
V
D
G
G
S
Q
A
Site 4
S147
G
A
S
V
D
G
G
S
Q
A
V
Q
G
G
G
Site 5
S189
P
D
A
G
G
C
A
S
E
E
N
G
V
L
R
Site 6
S205
K
H
E
A
V
D
H
S
S
Q
H
E
E
N
E
Site 7
S206
H
E
A
V
D
H
S
S
Q
H
E
E
N
E
E
Site 8
S216
E
E
N
E
E
R
V
S
A
Q
K
E
N
S
L
Site 9
S222
V
S
A
Q
K
E
N
S
L
Q
Q
N
D
D
D
Site 10
T244
P
D
W
E
A
E
K
T
T
E
S
R
N
E
R
Site 11
T256
N
E
R
H
L
N
G
T
D
T
S
F
S
L
E
Site 12
T258
R
H
L
N
G
T
D
T
S
F
S
L
E
D
L
Site 13
S259
H
L
N
G
T
D
T
S
F
S
L
E
D
L
F
Site 14
S261
N
G
T
D
T
S
F
S
L
E
D
L
F
Q
L
Site 15
S270
E
D
L
F
Q
L
L
S
S
Q
P
E
N
S
L
Site 16
S271
D
L
F
Q
L
L
S
S
Q
P
E
N
S
L
E
Site 17
S276
L
S
S
Q
P
E
N
S
L
E
G
I
S
L
G
Site 18
S281
E
N
S
L
E
G
I
S
L
G
D
I
P
L
P
Site 19
S290
G
D
I
P
L
P
G
S
I
S
D
G
M
N
S
Site 20
S292
I
P
L
P
G
S
I
S
D
G
M
N
S
S
A
Site 21
Y301
G
M
N
S
S
A
H
Y
H
V
N
F
S
Q
A
Site 22
S310
V
N
F
S
Q
A
I
S
Q
D
V
N
L
H
E
Site 23
T326
I
L
L
C
P
N
N
T
F
R
R
D
P
T
A
Site 24
T332
N
T
F
R
R
D
P
T
A
R
T
S
Q
S
Q
Site 25
S336
R
D
P
T
A
R
T
S
Q
S
Q
E
P
F
L
Site 26
S338
P
T
A
R
T
S
Q
S
Q
E
P
F
L
Q
L
Site 27
S366
T
N
L
T
G
F
L
S
P
V
D
N
H
M
R
Site 28
T376
D
N
H
M
R
N
L
T
S
Q
D
L
L
Y
D
Site 29
S377
N
H
M
R
N
L
T
S
Q
D
L
L
Y
D
L
Site 30
S396
F
D
E
I
N
L
M
S
L
A
T
E
D
N
F
Site 31
S409
N
F
D
P
I
D
V
S
Q
L
F
D
E
P
D
Site 32
S417
Q
L
F
D
E
P
D
S
D
S
G
L
S
L
D
Site 33
S419
F
D
E
P
D
S
D
S
G
L
S
L
D
S
S
Site 34
S422
P
D
S
D
S
G
L
S
L
D
S
S
H
N
N
Site 35
S425
D
S
G
L
S
L
D
S
S
H
N
N
T
S
V
Site 36
S426
S
G
L
S
L
D
S
S
H
N
N
T
S
V
I
Site 37
T430
L
D
S
S
H
N
N
T
S
V
I
K
S
N
S
Site 38
S431
D
S
S
H
N
N
T
S
V
I
K
S
N
S
S
Site 39
S435
N
N
T
S
V
I
K
S
N
S
S
H
S
V
C
Site 40
S437
T
S
V
I
K
S
N
S
S
H
S
V
C
D
E
Site 41
S438
S
V
I
K
S
N
S
S
H
S
V
C
D
E
G
Site 42
S440
I
K
S
N
S
S
H
S
V
C
D
E
G
A
I
Site 43
T451
E
G
A
I
G
Y
C
T
D
H
E
S
S
S
H
Site 44
Y469
E
G
A
V
G
G
Y
Y
P
E
P
S
K
L
C
Site 45
S481
K
L
C
H
L
D
Q
S
D
S
D
F
H
G
D
Site 46
S483
C
H
L
D
Q
S
D
S
D
F
H
G
D
L
T
Site 47
T505
H
T
Y
H
L
Q
P
T
A
P
E
S
T
S
E
Site 48
S509
L
Q
P
T
A
P
E
S
T
S
E
P
F
P
W
Site 49
T510
Q
P
T
A
P
E
S
T
S
E
P
F
P
W
P
Site 50
S511
P
T
A
P
E
S
T
S
E
P
F
P
W
P
G
Site 51
S520
P
F
P
W
P
G
K
S
Q
K
I
R
S
R
Y
Site 52
S525
G
K
S
Q
K
I
R
S
R
Y
L
E
D
T
D
Site 53
Y527
S
Q
K
I
R
S
R
Y
L
E
D
T
D
R
N
Site 54
T531
R
S
R
Y
L
E
D
T
D
R
N
L
S
R
D
Site 55
S536
E
D
T
D
R
N
L
S
R
D
E
Q
R
A
K
Site 56
S567
D
S
F
N
S
M
L
S
R
Y
Y
L
T
D
L
Site 57
Y570
N
S
M
L
S
R
Y
Y
L
T
D
L
Q
V
S
Site 58
Y642
K
Q
K
L
H
D
L
Y
H
D
I
F
S
R
L
Site 59
Y662
R
P
V
N
P
N
H
Y
A
L
Q
C
T
H
D
Site 60
S682
V
P
K
E
L
V
A
S
G
H
K
K
E
T
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation