KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM115A
Full Name:
Protein FAM115A
Alias:
Type:
Mass (Da):
102126
Number AA:
921
UniProt ID:
Q9Y4C2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S63
R
G
R
L
V
V
V
S
H
E
D
Y
L
V
E
Site 2
Y125
V
K
D
S
L
G
V
Y
C
I
D
A
Y
N
E
Site 3
Y130
G
V
Y
C
I
D
A
Y
N
E
T
M
T
E
K
Site 4
T169
E
D
E
R
V
L
F
T
F
P
G
N
L
V
T
Site 5
Y182
V
T
S
V
A
G
I
Y
F
T
D
N
K
G
D
Site 6
S191
T
D
N
K
G
D
T
S
F
F
K
V
S
K
K
Site 7
S207
P
K
I
P
V
L
V
S
C
E
D
D
L
S
D
Site 8
S213
V
S
C
E
D
D
L
S
D
D
R
E
E
L
L
Site 9
S224
E
E
L
L
H
G
I
S
E
L
D
I
S
N
S
Site 10
S229
G
I
S
E
L
D
I
S
N
S
D
C
F
P
S
Site 11
S231
S
E
L
D
I
S
N
S
D
C
F
P
S
Q
L
Site 12
S236
S
N
S
D
C
F
P
S
Q
L
L
V
H
G
A
Site 13
T305
R
G
K
V
V
V
Q
T
E
L
R
T
L
S
G
Site 14
T328
T
S
I
E
P
N
L
T
S
D
A
S
V
Y
C
Site 15
S332
P
N
L
T
S
D
A
S
V
Y
C
F
E
P
V
Site 16
S374
A
F
K
N
P
G
V
S
P
L
A
R
F
P
G
Site 17
S394
P
F
G
I
S
I
T
S
Q
S
L
N
P
G
P
Site 18
S396
G
I
S
I
T
S
Q
S
L
N
P
G
P
F
R
Site 19
T404
L
N
P
G
P
F
R
T
P
K
A
G
I
R
T
Site 20
Y412
P
K
A
G
I
R
T
Y
H
F
R
S
T
L
A
Site 21
T417
R
T
Y
H
F
R
S
T
L
A
E
F
Q
V
I
Site 22
S460
E
E
I
P
A
Y
M
S
V
H
R
L
L
R
K
Site 23
S470
R
L
L
R
K
L
L
S
R
Y
R
L
P
V
A
Site 24
Y472
L
R
K
L
L
S
R
Y
R
L
P
V
A
T
R
Site 25
T478
R
Y
R
L
P
V
A
T
R
E
N
P
V
I
N
Site 26
Y517
V
P
E
I
E
D
M
Y
S
S
P
Y
L
R
P
Site 27
S518
P
E
I
E
D
M
Y
S
S
P
Y
L
R
P
S
Site 28
S519
E
I
E
D
M
Y
S
S
P
Y
L
R
P
S
E
Site 29
Y521
E
D
M
Y
S
S
P
Y
L
R
P
S
E
S
P
Site 30
S525
S
S
P
Y
L
R
P
S
E
S
P
I
T
V
E
Site 31
S527
P
Y
L
R
P
S
E
S
P
I
T
V
E
V
N
Site 32
T530
R
P
S
E
S
P
I
T
V
E
V
N
C
T
N
Site 33
T536
I
T
V
E
V
N
C
T
N
P
G
T
R
Y
C
Site 34
T582
G
C
H
T
D
D
L
T
R
A
S
K
L
F
R
Site 35
S585
T
D
D
L
T
R
A
S
K
L
F
R
G
P
L
Site 36
S626
P
Q
N
S
K
L
G
S
V
P
V
T
V
K
G
Site 37
Y639
K
G
A
V
H
A
P
Y
Y
K
L
G
E
T
T
Site 38
Y640
G
A
V
H
A
P
Y
Y
K
L
G
E
T
T
L
Site 39
T774
E
W
E
F
P
P
H
T
T
E
A
T
C
N
L
Site 40
Y814
R
E
K
R
V
R
I
Y
L
S
K
G
P
N
V
Site 41
S816
K
R
V
R
I
Y
L
S
K
G
P
N
V
K
N
Site 42
T850
E
P
F
I
R
L
F
T
E
Y
R
N
Q
T
N
Site 43
Y852
F
I
R
L
F
T
E
Y
R
N
Q
T
N
L
P
Site 44
T856
F
T
E
Y
R
N
Q
T
N
L
P
T
E
N
V
Site 45
S874
N
L
W
V
K
M
F
S
H
Q
V
Q
K
N
L
Site 46
S899
I
Q
K
E
V
A
T
S
L
A
Y
L
P
E
W
Site 47
Y914
K
E
N
I
M
K
L
Y
L
L
T
Q
M
P
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation