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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR7
Full Name:
WD repeat-containing protein 7
Alias:
KIAA0541; Rabconnectin-3 beta; TGF-beta resistance-associated protein TRAG; TRAG; WD repeat domain 7; WD-repeat protein 7
Type:
Vesicle protein
Mass (Da):
163810
Number AA:
1490
UniProt ID:
Q9Y4E6
International Prot ID:
IPI00289815
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y81
C
A
S
S
D
K
Q
Y
I
V
S
A
S
E
S
Site 2
S84
S
D
K
Q
Y
I
V
S
A
S
E
S
G
E
M
Site 3
S86
K
Q
Y
I
V
S
A
S
E
S
G
E
M
C
L
Site 4
S88
Y
I
V
S
A
S
E
S
G
E
M
C
L
W
D
Site 5
S97
E
M
C
L
W
D
V
S
D
G
R
C
I
E
F
Site 6
T112
T
K
L
A
C
T
H
T
G
I
Q
F
Y
Q
F
Site 7
Y117
T
H
T
G
I
Q
F
Y
Q
F
S
V
G
N
Q
Site 8
S120
G
I
Q
F
Y
Q
F
S
V
G
N
Q
R
E
G
Site 9
S157
Y
S
L
V
S
K
I
S
P
D
W
I
S
S
M
Site 10
S162
K
I
S
P
D
W
I
S
S
M
S
I
I
R
S
Site 11
S163
I
S
P
D
W
I
S
S
M
S
I
I
R
S
H
Site 12
S165
P
D
W
I
S
S
M
S
I
I
R
S
H
R
T
Site 13
S169
S
S
M
S
I
I
R
S
H
R
T
Q
E
D
T
Site 14
T176
S
H
R
T
Q
E
D
T
V
V
A
L
S
V
T
Site 15
T201
E
I
S
D
M
Q
D
T
E
P
I
F
E
E
E
Site 16
Y213
E
E
E
S
K
P
I
Y
C
Q
N
C
Q
S
I
Site 17
Y246
R
V
F
D
A
G
D
Y
S
L
L
C
S
G
P
Site 18
S251
G
D
Y
S
L
L
C
S
G
P
S
E
N
G
Q
Site 19
S254
S
L
L
C
S
G
P
S
E
N
G
Q
T
W
T
Site 20
T259
G
P
S
E
N
G
Q
T
W
T
G
G
D
F
V
Site 21
T275
S
D
K
V
I
I
W
T
E
N
G
Q
S
Y
I
Site 22
Y283
E
N
G
Q
S
Y
I
Y
K
L
P
A
S
C
L
Site 23
S288
Y
I
Y
K
L
P
A
S
C
L
P
A
S
D
S
Site 24
S293
P
A
S
C
L
P
A
S
D
S
F
R
S
D
V
Site 25
S295
S
C
L
P
A
S
D
S
F
R
S
D
V
G
K
Site 26
S298
P
A
S
D
S
F
R
S
D
V
G
K
A
V
E
Site 27
Y334
P
P
V
T
R
F
F
Y
G
C
R
E
Y
F
H
Site 28
S349
K
L
L
I
Q
G
D
S
S
G
R
L
N
I
W
Site 29
S350
L
L
I
Q
G
D
S
S
G
R
L
N
I
W
N
Site 30
S359
R
L
N
I
W
N
I
S
D
T
A
D
K
Q
G
Site 31
T361
N
I
W
N
I
S
D
T
A
D
K
Q
G
S
E
Site 32
T374
S
E
E
G
L
A
M
T
T
S
I
S
L
Q
E
Site 33
S403
Q
L
S
V
I
P
N
S
N
E
P
L
K
V
T
Site 34
T459
R
G
W
P
P
H
R
T
L
R
G
H
R
N
K
Site 35
T468
R
G
H
R
N
K
V
T
C
L
L
Y
P
H
Q
Site 36
Y472
N
K
V
T
C
L
L
Y
P
H
Q
V
S
A
R
Site 37
S477
L
L
Y
P
H
Q
V
S
A
R
Y
D
Q
R
Y
Site 38
Y480
P
H
Q
V
S
A
R
Y
D
Q
R
Y
L
I
S
Site 39
Y484
S
A
R
Y
D
Q
R
Y
L
I
S
G
G
V
D
Site 40
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Site 41
S571
Q
V
I
K
W
R
P
S
D
D
Y
L
V
V
G
Site 42
Y574
K
W
R
P
S
D
D
Y
L
V
V
G
C
S
D
Site 43
Y585
G
C
S
D
G
S
V
Y
V
W
Q
M
D
T
G
Site 44
S636
K
Q
A
M
T
R
R
S
L
A
A
L
K
N
M
Site 45
T650
M
A
H
H
K
L
Q
T
L
A
T
N
L
L
A
Site 46
T653
H
K
L
Q
T
L
A
T
N
L
L
A
S
E
A
Site 47
S658
L
A
T
N
L
L
A
S
E
A
S
D
K
G
N
Site 48
S661
N
L
L
A
S
E
A
S
D
K
G
N
L
P
K
Site 49
Y669
D
K
G
N
L
P
K
Y
S
H
N
S
L
M
V
Site 50
T712
E
E
A
S
R
P
N
T
A
L
I
S
P
E
N
Site 51
S716
R
P
N
T
A
L
I
S
P
E
N
L
Q
K
A
Site 52
S724
P
E
N
L
Q
K
A
S
G
S
S
D
K
G
G
Site 53
S726
N
L
Q
K
A
S
G
S
S
D
K
G
G
S
F
Site 54
S732
G
S
S
D
K
G
G
S
F
L
T
G
K
R
A
Site 55
S776
M
R
Q
R
R
E
E
S
D
P
E
Y
R
S
S
Site 56
Y780
R
E
E
S
D
P
E
Y
R
S
S
K
S
K
P
Site 57
S782
E
S
D
P
E
Y
R
S
S
K
S
K
P
L
T
Site 58
S783
S
D
P
E
Y
R
S
S
K
S
K
P
L
T
L
Site 59
S785
P
E
Y
R
S
S
K
S
K
P
L
T
L
L
E
Site 60
T789
S
S
K
S
K
P
L
T
L
L
E
Y
N
L
T
Site 61
Y793
K
P
L
T
L
L
E
Y
N
L
T
M
D
T
A
Site 62
T799
E
Y
N
L
T
M
D
T
A
K
L
F
M
S
C
Site 63
S839
T
V
S
F
G
L
L
S
R
G
G
H
M
S
L
Site 64
S845
L
S
R
G
G
H
M
S
L
M
L
P
G
Y
N
Site 65
S859
N
Q
P
A
C
K
L
S
H
G
K
T
E
V
G
Site 66
T863
C
K
L
S
H
G
K
T
E
V
G
R
K
L
P
Site 67
S872
V
G
R
K
L
P
A
S
E
G
V
G
K
G
T
Site 68
T879
S
E
G
V
G
K
G
T
Y
G
V
S
R
A
V
Site 69
Y880
E
G
V
G
K
G
T
Y
G
V
S
R
A
V
T
Site 70
S883
G
K
G
T
Y
G
V
S
R
A
V
T
T
Q
H
Site 71
T919
D
H
M
K
K
G
P
T
R
P
P
R
P
S
T
Site 72
S925
P
T
R
P
P
R
P
S
T
P
D
L
S
K
A
Site 73
T926
T
R
P
P
R
P
S
T
P
D
L
S
K
A
R
Site 74
S930
R
P
S
T
P
D
L
S
K
A
R
G
S
P
P
Site 75
S935
D
L
S
K
A
R
G
S
P
P
T
S
S
N
I
Site 76
T938
K
A
R
G
S
P
P
T
S
S
N
I
V
Q
G
Site 77
S939
A
R
G
S
P
P
T
S
S
N
I
V
Q
G
Q
Site 78
S940
R
G
S
P
P
T
S
S
N
I
V
Q
G
Q
I
Site 79
S964
A
R
S
D
A
D
H
S
G
S
D
P
P
S
A
Site 80
S966
S
D
A
D
H
S
G
S
D
P
P
S
A
P
A
Site 81
S970
H
S
G
S
D
P
P
S
A
P
A
L
H
T
C
Site 82
Y1053
A
I
D
A
W
A
P
Y
L
P
Q
Y
I
D
H
Site 83
Y1057
W
A
P
Y
L
P
Q
Y
I
D
H
V
I
S
P
Site 84
S1063
Q
Y
I
D
H
V
I
S
P
G
V
T
S
E
A
Site 85
T1073
V
T
S
E
A
A
Q
T
I
T
T
A
P
D
A
Site 86
S1116
Q
M
K
K
I
S
T
S
Y
E
E
R
R
K
Q
Site 87
T1125
E
E
R
R
K
Q
A
T
A
I
V
L
L
G
V
Site 88
T1148
I
E
P
P
K
L
L
T
R
P
R
S
S
S
Q
Site 89
S1152
K
L
L
T
R
P
R
S
S
S
Q
I
P
E
G
Site 90
S1153
L
L
T
R
P
R
S
S
S
Q
I
P
E
G
F
Site 91
S1154
L
T
R
P
R
S
S
S
Q
I
P
E
G
F
G
Site 92
T1163
I
P
E
G
F
G
L
T
S
G
G
S
N
Y
S
Site 93
S1164
P
E
G
F
G
L
T
S
G
G
S
N
Y
S
L
Site 94
S1167
F
G
L
T
S
G
G
S
N
Y
S
L
A
R
H
Site 95
S1170
T
S
G
G
S
N
Y
S
L
A
R
H
T
C
K
Site 96
S1188
F
L
L
L
Q
P
P
S
P
K
L
P
P
H
S
Site 97
S1195
S
P
K
L
P
P
H
S
T
I
R
R
T
A
I
Site 98
T1196
P
K
L
P
P
H
S
T
I
R
R
T
A
I
D
Site 99
T1200
P
H
S
T
I
R
R
T
A
I
D
L
I
G
R
Site 100
T1210
D
L
I
G
R
G
F
T
V
W
E
P
Y
M
D
Site 101
T1240
E
K
Q
L
A
N
I
T
M
G
L
P
L
S
P
Site 102
S1246
I
T
M
G
L
P
L
S
P
A
A
D
S
A
R
Site 103
S1251
P
L
S
P
A
A
D
S
A
R
S
A
R
H
A
Site 104
S1254
P
A
A
D
S
A
R
S
A
R
H
A
L
S
L
Site 105
S1260
R
S
A
R
H
A
L
S
L
I
A
T
A
R
P
Site 106
T1273
R
P
P
A
F
I
T
T
I
A
K
E
V
H
R
Site 107
T1282
A
K
E
V
H
R
H
T
A
L
A
A
N
T
Q
Site 108
Y1357
F
P
A
I
C
R
F
Y
M
V
S
Y
Y
E
R
Site 109
Y1361
C
R
F
Y
M
V
S
Y
Y
E
R
N
H
R
I
Site 110
Y1362
R
F
Y
M
V
S
Y
Y
E
R
N
H
R
I
A
Site 111
Y1380
R
H
G
S
V
A
L
Y
D
I
R
T
G
K
C
Site 112
T1384
V
A
L
Y
D
I
R
T
G
K
C
Q
T
I
H
Site 113
T1398
H
G
H
K
G
P
I
T
A
V
A
F
A
P
D
Site 114
Y1408
A
F
A
P
D
G
R
Y
L
A
T
Y
S
N
T
Site 115
T1411
P
D
G
R
Y
L
A
T
Y
S
N
T
D
S
H
Site 116
Y1412
D
G
R
Y
L
A
T
Y
S
N
T
D
S
H
I
Site 117
S1413
G
R
Y
L
A
T
Y
S
N
T
D
S
H
I
S
Site 118
T1446
P
Q
L
R
C
I
K
T
Y
Q
V
P
P
V
Q
Site 119
Y1447
Q
L
R
C
I
K
T
Y
Q
V
P
P
V
Q
P
Site 120
S1456
V
P
P
V
Q
P
A
S
P
G
S
H
N
A
L
Site 121
S1459
V
Q
P
A
S
P
G
S
H
N
A
L
K
L
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation