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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LOXL2
Full Name:
Lysyl oxidase homolog 2
Alias:
Lysyl oxidase-like protein 2;Lysyl oxidase-related protein 2;Lysyl oxidase-related protein WS9-14
Type:
Mass (Da):
86725
Number AA:
774
UniProt ID:
Q9Y4K0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
S
P
L
S
L
A
Q
Y
D
S
W
P
H
Y
P
Site 2
S29
L
S
L
A
Q
Y
D
S
W
P
H
Y
P
E
Y
Site 3
Y36
S
W
P
H
Y
P
E
Y
F
Q
Q
P
A
P
E
Site 4
Y44
F
Q
Q
P
A
P
E
Y
H
Q
P
Q
A
P
A
Site 5
S68
A
G
Q
K
R
K
H
S
E
G
R
V
E
V
Y
Site 6
Y75
S
E
G
R
V
E
V
Y
Y
D
G
Q
W
G
T
Site 7
Y76
E
G
R
V
E
V
Y
Y
D
G
Q
W
G
T
V
Site 8
Y102
V
V
C
R
E
L
G
Y
V
E
A
K
S
W
T
Site 9
S107
L
G
Y
V
E
A
K
S
W
T
A
S
S
S
Y
Site 10
T109
Y
V
E
A
K
S
W
T
A
S
S
S
Y
G
K
Site 11
S111
E
A
K
S
W
T
A
S
S
S
Y
G
K
G
E
Site 12
S112
A
K
S
W
T
A
S
S
S
Y
G
K
G
E
G
Site 13
S113
K
S
W
T
A
S
S
S
Y
G
K
G
E
G
P
Site 14
S159
E
D
V
G
V
V
C
S
D
K
R
I
P
G
F
Site 15
S171
P
G
F
K
F
D
N
S
L
I
N
Q
I
E
N
Site 16
S193
I
R
I
R
A
I
L
S
T
Y
R
K
R
T
P
Site 17
T194
R
I
R
A
I
L
S
T
Y
R
K
R
T
P
V
Site 18
Y195
I
R
A
I
L
S
T
Y
R
K
R
T
P
V
M
Site 19
T199
L
S
T
Y
R
K
R
T
P
V
M
E
G
Y
V
Site 20
Y205
R
T
P
V
M
E
G
Y
V
E
V
K
E
G
K
Site 21
Y242
G
F
P
G
E
R
T
Y
N
T
K
V
Y
K
M
Site 22
Y247
R
T
Y
N
T
K
V
Y
K
M
F
A
S
R
R
Site 23
Y258
A
S
R
R
K
Q
R
Y
W
P
F
S
M
D
C
Site 24
T268
F
S
M
D
C
T
G
T
E
A
H
I
S
S
C
Site 25
S273
T
G
T
E
A
H
I
S
S
C
K
L
G
P
Q
Site 26
S282
C
K
L
G
P
Q
V
S
L
D
P
M
K
N
V
Site 27
S308
C
V
P
G
Q
V
F
S
P
D
G
P
S
R
F
Site 28
Y319
P
S
R
F
R
K
A
Y
K
P
E
Q
P
L
V
Site 29
S379
A
K
E
A
V
T
G
S
R
L
G
Q
G
I
G
Site 30
T396
H
L
N
E
I
Q
C
T
G
N
E
K
S
I
I
Site 31
T426
D
A
G
V
R
C
N
T
P
A
M
G
L
Q
K
Site 32
Y444
L
N
G
G
R
N
P
Y
E
G
R
V
E
V
L
Site 33
S507
N
S
N
K
V
V
M
S
G
V
K
C
S
G
T
Site 34
S517
K
C
S
G
T
E
L
S
L
A
H
C
R
H
D
Site 35
Y562
E
M
V
Q
Q
T
T
Y
L
E
D
R
P
M
F
Site 36
S581
A
M
E
E
N
C
L
S
A
S
A
A
Q
T
D
Site 37
T587
L
S
A
S
A
A
Q
T
D
P
T
T
G
Y
R
Site 38
T590
S
A
A
Q
T
D
P
T
T
G
Y
R
R
L
L
Site 39
T591
A
A
Q
T
D
P
T
T
G
Y
R
R
L
L
R
Site 40
Y593
Q
T
D
P
T
T
G
Y
R
R
L
L
R
F
S
Site 41
S600
Y
R
R
L
L
R
F
S
S
Q
I
H
N
N
G
Site 42
S601
R
R
L
L
R
F
S
S
Q
I
H
N
N
G
Q
Site 43
S609
Q
I
H
N
N
G
Q
S
D
F
R
P
K
N
G
Site 44
Y638
S
M
E
V
F
T
H
Y
D
L
L
N
L
N
G
Site 45
T646
D
L
L
N
L
N
G
T
K
V
A
E
G
H
K
Site 46
S655
V
A
E
G
H
K
A
S
F
C
L
E
D
T
E
Site 47
T661
A
S
F
C
L
E
D
T
E
C
E
G
D
I
Q
Site 48
Y671
E
G
D
I
Q
K
N
Y
E
C
A
N
F
G
D
Site 49
Y725
F
E
V
A
E
S
D
Y
S
N
N
I
M
K
C
Site 50
S751
Y
N
C
H
I
G
G
S
F
S
E
E
T
E
K
Site 51
S753
C
H
I
G
G
S
F
S
E
E
T
E
K
K
F
Site 52
T756
G
G
S
F
S
E
E
T
E
K
K
F
E
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation