KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TBL2
Full Name:
Transducin beta-like protein 2
Alias:
DKFZP43N024; Transducin (beta)-like 2; Transducin beta-like 2; WBSCR13; Williams-Beuren syndrome chromosome region 13; WS beta-transducin repeats protein; WS-betaTRP
Type:
Unknown function
Mass (Da):
49798
Number AA:
447
UniProt ID:
Q9Y4P3
International Prot ID:
IPI00000948
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S39
L
R
A
G
E
E
R
S
G
R
P
A
C
Q
K
Site 2
S55
N
G
F
P
P
D
K
S
S
G
S
K
K
Q
K
Site 3
S56
G
F
P
P
D
K
S
S
G
S
K
K
Q
K
Q
Site 4
Y64
G
S
K
K
Q
K
Q
Y
Q
R
I
R
K
E
K
Site 5
S90
A
A
A
L
K
S
H
S
G
N
I
S
C
M
D
Site 6
S94
K
S
H
S
G
N
I
S
C
M
D
F
S
S
N
Site 7
Y104
D
F
S
S
N
G
K
Y
L
A
T
C
A
D
D
Site 8
T113
A
T
C
A
D
D
R
T
I
R
I
W
S
T
K
Site 9
S118
D
R
T
I
R
I
W
S
T
K
D
F
L
Q
R
Site 10
S129
F
L
Q
R
E
H
R
S
M
R
A
N
V
E
L
Site 11
T140
N
V
E
L
D
H
A
T
L
V
R
F
S
P
D
Site 12
T167
T
L
R
V
F
K
M
T
K
R
E
D
G
G
Y
Site 13
Y174
T
K
R
E
D
G
G
Y
T
F
T
A
T
P
E
Site 14
T175
K
R
E
D
G
G
Y
T
F
T
A
T
P
E
D
Site 15
T177
E
D
G
G
Y
T
F
T
A
T
P
E
D
F
P
Site 16
T179
G
G
Y
T
F
T
A
T
P
E
D
F
P
K
K
Site 17
S223
S
L
K
G
Q
V
L
S
T
I
N
T
N
Q
M
Site 18
S238
N
N
T
H
A
A
V
S
P
C
G
R
F
V
A
Site 19
S284
G
H
S
A
A
V
H
S
F
A
F
S
N
D
S
Site 20
S288
A
V
H
S
F
A
F
S
N
D
S
R
R
M
A
Site 21
S291
S
F
A
F
S
N
D
S
R
R
M
A
S
V
S
Site 22
S296
N
D
S
R
R
M
A
S
V
S
K
D
G
T
W
Site 23
S298
S
R
R
M
A
S
V
S
K
D
G
T
W
K
L
Site 24
T302
A
S
V
S
K
D
G
T
W
K
L
W
D
T
D
Site 25
Y312
L
W
D
T
D
V
E
Y
K
K
K
Q
D
P
Y
Site 26
Y319
Y
K
K
K
Q
D
P
Y
L
L
K
T
G
R
F
Site 27
T323
Q
D
P
Y
L
L
K
T
G
R
F
E
E
A
A
Site 28
Y357
S
G
S
S
I
H
L
Y
N
T
R
R
G
E
K
Site 29
T402
A
V
R
L
F
H
N
T
P
G
H
R
A
M
V
Site 30
S420
Q
G
H
L
K
R
A
S
N
E
S
T
R
Q
R
Site 31
S423
L
K
R
A
S
N
E
S
T
R
Q
R
L
Q
Q
Site 32
T424
K
R
A
S
N
E
S
T
R
Q
R
L
Q
Q
Q
Site 33
T433
Q
R
L
Q
Q
Q
L
T
Q
A
Q
E
T
L
K
Site 34
S441
Q
A
Q
E
T
L
K
S
L
G
A
L
K
K
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation