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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TELO2
Full Name:
Telomere length regulation protein TEL2 homolog
Alias:
Clk-2 homologue; KIAA0683; Protein clk-2 homolog; TEL2, telomere maintenance 2,
Type:
Mass (Da):
91747
Number AA:
837
UniProt ID:
Q9Y4R8
International Prot ID:
IPI00016868
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000781
GO:0005737
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
P
A
P
S
E
V
R
L
A
V
R
Site 2
S20
R
E
A
I
H
A
L
S
S
S
E
D
G
G
H
Site 3
S21
E
A
I
H
A
L
S
S
S
E
D
G
G
H
I
Site 4
S22
A
I
H
A
L
S
S
S
E
D
G
G
H
I
F
Site 5
T31
D
G
G
H
I
F
C
T
L
E
S
L
K
R
Y
Site 6
S34
H
I
F
C
T
L
E
S
L
K
R
Y
L
G
E
Site 7
Y38
T
L
E
S
L
K
R
Y
L
G
E
M
E
P
P
Site 8
S56
R
E
K
E
E
F
A
S
A
H
F
S
P
V
L
Site 9
T145
E
A
Q
C
R
Q
Q
T
Q
P
G
F
I
L
L
Site 10
Y184
A
E
F
F
P
Q
N
Y
F
R
L
L
G
E
E
Site 11
S209
S
L
Q
G
G
L
D
S
S
V
S
F
V
S
Q
Site 12
T242
V
P
R
L
A
A
L
T
Q
G
S
Y
L
H
Q
Site 13
Y246
A
A
L
T
Q
G
S
Y
L
H
Q
R
V
C
W
Site 14
T269
R
A
M
E
A
V
L
T
G
L
V
E
A
A
L
Site 15
S326
L
G
H
L
A
M
D
S
Q
R
R
P
L
L
L
Site 16
S345
E
L
L
E
T
W
G
S
S
S
A
I
R
H
T
Site 17
S347
L
E
T
W
G
S
S
S
A
I
R
H
T
P
L
Site 18
T352
S
S
S
A
I
R
H
T
P
L
P
Q
Q
R
H
Site 19
S379
G
E
P
E
L
R
D
S
R
D
E
L
L
A
S
Site 20
S397
G
V
K
C
R
L
D
S
S
L
P
P
V
R
R
Site 21
S398
V
K
C
R
L
D
S
S
L
P
P
V
R
R
L
Site 22
Y428
G
P
P
L
K
F
Q
Y
E
E
D
E
L
S
L
Site 23
S434
Q
Y
E
E
D
E
L
S
L
E
L
L
A
L
A
Site 24
S451
Q
P
A
G
D
G
A
S
E
A
G
T
S
L
V
Site 25
S456
G
A
S
E
A
G
T
S
L
V
P
A
T
A
E
Site 26
T461
G
T
S
L
V
P
A
T
A
E
P
P
A
E
T
Site 27
T468
T
A
E
P
P
A
E
T
P
A
E
I
V
D
G
Site 28
S485
P
Q
A
Q
L
A
G
S
D
S
D
L
D
S
D
Site 29
S487
A
Q
L
A
G
S
D
S
D
L
D
S
D
D
E
Site 30
S491
G
S
D
S
D
L
D
S
D
D
E
F
V
P
Y
Site 31
Y498
S
D
D
E
F
V
P
Y
D
M
S
G
D
R
E
Site 32
S501
E
F
V
P
Y
D
M
S
G
D
R
E
L
K
S
Site 33
S508
S
G
D
R
E
L
K
S
S
K
A
P
A
Y
V
Site 34
S509
G
D
R
E
L
K
S
S
K
A
P
A
Y
V
R
Site 35
Y514
K
S
S
K
A
P
A
Y
V
R
D
C
V
E
A
Site 36
T524
D
C
V
E
A
L
T
T
S
E
D
I
E
R
W
Site 37
Y543
R
A
L
E
G
L
V
Y
R
S
P
T
A
T
R
Site 38
S545
L
E
G
L
V
Y
R
S
P
T
A
T
R
E
V
Site 39
T547
G
L
V
Y
R
S
P
T
A
T
R
E
V
S
V
Site 40
T549
V
Y
R
S
P
T
A
T
R
E
V
S
V
E
L
Site 41
Y594
D
P
A
P
V
A
D
Y
L
T
S
Q
F
Y
A
Site 42
Y600
D
Y
L
T
S
Q
F
Y
A
L
N
Y
S
L
R
Site 43
T632
R
P
G
C
L
G
R
T
P
Q
P
G
S
P
S
Site 44
S637
G
R
T
P
Q
P
G
S
P
S
P
N
T
P
C
Site 45
S639
T
P
Q
P
G
S
P
S
P
N
T
P
C
L
P
Site 46
T642
P
G
S
P
S
P
N
T
P
C
L
P
E
A
A
Site 47
S655
A
A
V
S
Q
P
G
S
A
V
A
S
D
W
R
Site 48
S659
Q
P
G
S
A
V
A
S
D
W
R
V
V
V
E
Site 49
S671
V
V
E
E
R
I
R
S
K
T
Q
R
L
S
K
Site 50
T673
E
E
R
I
R
S
K
T
Q
R
L
S
K
G
G
Site 51
S677
R
S
K
T
Q
R
L
S
K
G
G
P
R
Q
G
Site 52
S688
P
R
Q
G
P
A
G
S
P
S
R
F
N
S
V
Site 53
S690
Q
G
P
A
G
S
P
S
R
F
N
S
V
A
G
Site 54
S694
G
S
P
S
R
F
N
S
V
A
G
H
F
F
F
Site 55
T713
R
F
D
R
P
L
V
T
F
D
L
L
G
E
D
Site 56
T815
D
P
D
E
D
C
R
T
L
A
L
R
A
L
L
Site 57
S836
N
R
L
L
P
P
A
S
P
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation