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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AMMECR1
Full Name:
AMME syndrome candidate gene 1 protein
Alias:
Type:
Mass (Da):
35445
Number AA:
333
UniProt ID:
Q9Y4X0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
G
V
K
K
Q
K
L
S
S
S
P
P
S
G
S
Site 2
S15
V
K
K
Q
K
L
S
S
S
P
P
S
G
S
G
Site 3
S16
K
K
Q
K
L
S
S
S
P
P
S
G
S
G
G
Site 4
S19
K
L
S
S
S
P
P
S
G
S
G
G
G
G
G
Site 5
S21
S
S
S
P
P
S
G
S
G
G
G
G
G
A
S
Site 6
S28
S
G
G
G
G
G
A
S
S
S
S
H
C
S
G
Site 7
S29
G
G
G
G
G
A
S
S
S
S
H
C
S
G
E
Site 8
S30
G
G
G
G
A
S
S
S
S
H
C
S
G
E
S
Site 9
S31
G
G
G
A
S
S
S
S
H
C
S
G
E
S
Q
Site 10
S34
A
S
S
S
S
H
C
S
G
E
S
Q
C
R
A
Site 11
S37
S
S
H
C
S
G
E
S
Q
C
R
A
G
E
L
Site 12
S66
L
T
G
G
G
S
G
S
G
C
T
L
S
P
P
Site 13
T69
G
G
S
G
S
G
C
T
L
S
P
P
Q
G
C
Site 14
S71
S
G
S
G
C
T
L
S
P
P
Q
G
C
G
G
Site 15
T104
L
S
T
P
A
A
A
T
S
S
S
P
S
S
S
Site 16
S105
S
T
P
A
A
A
T
S
S
S
P
S
S
S
S
Site 17
S106
T
P
A
A
A
T
S
S
S
P
S
S
S
S
A
Site 18
S107
P
A
A
A
T
S
S
S
P
S
S
S
S
A
A
Site 19
S109
A
A
T
S
S
S
P
S
S
S
S
A
A
S
S
Site 20
S110
A
T
S
S
S
P
S
S
S
S
A
A
S
S
S
Site 21
S111
T
S
S
S
P
S
S
S
S
A
A
S
S
S
S
Site 22
S112
S
S
S
P
S
S
S
S
A
A
S
S
S
S
P
Site 23
S115
P
S
S
S
S
A
A
S
S
S
S
P
G
S
R
Site 24
S116
S
S
S
S
A
A
S
S
S
S
P
G
S
R
K
Site 25
S117
S
S
S
A
A
S
S
S
S
P
G
S
R
K
M
Site 26
S118
S
S
A
A
S
S
S
S
P
G
S
R
K
M
V
Site 27
S121
A
S
S
S
S
P
G
S
R
K
M
V
V
S
A
Site 28
Y143
D
V
L
Y
C
H
L
Y
G
Y
Q
Q
P
R
T
Site 29
Y145
L
Y
C
H
L
Y
G
Y
Q
Q
P
R
T
P
R
Site 30
T150
Y
G
Y
Q
Q
P
R
T
P
R
F
T
N
E
P
Site 31
T154
Q
P
R
T
P
R
F
T
N
E
P
Y
P
L
F
Site 32
Y158
P
R
F
T
N
E
P
Y
P
L
F
V
T
W
K
Site 33
S186
F
S
A
M
N
L
H
S
G
L
R
E
Y
T
L
Site 34
Y191
L
H
S
G
L
R
E
Y
T
L
T
S
A
L
K
Site 35
T192
H
S
G
L
R
E
Y
T
L
T
S
A
L
K
D
Site 36
T194
G
L
R
E
Y
T
L
T
S
A
L
K
D
S
R
Site 37
T206
D
S
R
F
P
P
M
T
R
D
E
L
P
R
L
Site 38
Y229
N
F
E
D
V
C
D
Y
L
D
W
E
V
G
V
Site 39
S249
E
F
I
N
E
K
G
S
K
R
T
A
T
Y
L
Site 40
T252
N
E
K
G
S
K
R
T
A
T
Y
L
P
E
V
Site 41
T254
K
G
S
K
R
T
A
T
Y
L
P
E
V
A
K
Site 42
T270
Q
G
W
D
H
I
Q
T
I
D
S
L
L
R
K
Site 43
S273
D
H
I
Q
T
I
D
S
L
L
R
K
G
G
Y
Site 44
Y280
S
L
L
R
K
G
G
Y
K
A
P
I
T
N
E
Site 45
T285
G
G
Y
K
A
P
I
T
N
E
F
R
K
T
I
Site 46
T291
I
T
N
E
F
R
K
T
I
K
L
T
R
Y
R
Site 47
T295
F
R
K
T
I
K
L
T
R
Y
R
S
E
K
M
Site 48
Y297
K
T
I
K
L
T
R
Y
R
S
E
K
M
T
L
Site 49
S299
I
K
L
T
R
Y
R
S
E
K
M
T
L
S
Y
Site 50
T303
R
Y
R
S
E
K
M
T
L
S
Y
A
E
Y
L
Site 51
S305
R
S
E
K
M
T
L
S
Y
A
E
Y
L
A
H
Site 52
Y306
S
E
K
M
T
L
S
Y
A
E
Y
L
A
H
R
Site 53
Y309
M
T
L
S
Y
A
E
Y
L
A
H
R
Q
H
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation