KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KLF12
Full Name:
Krueppel-like factor 12
Alias:
AP2REP; AP-2rep; HSPC122; Kruppel-like factor 12
Type:
Mass (Da):
44240
Number AA:
402
UniProt ID:
Q9Y4X4
International Prot ID:
IPI00027024
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003714
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
N
I
H
M
K
R
K
T
I
K
N
I
N
T
F
Site 2
T15
K
T
I
K
N
I
N
T
F
E
N
R
M
L
M
Site 3
T33
M
P
A
V
R
V
K
T
E
L
L
E
S
E
Q
Site 4
S38
V
K
T
E
L
L
E
S
E
Q
G
S
P
N
V
Site 5
S42
L
L
E
S
E
Q
G
S
P
N
V
H
N
Y
P
Site 6
Y48
G
S
P
N
V
H
N
Y
P
D
M
E
A
V
P
Site 7
S69
K
G
E
P
P
E
D
S
L
S
V
D
H
F
Q
Site 8
S71
E
P
P
E
D
S
L
S
V
D
H
F
Q
T
Q
Site 9
T79
V
D
H
F
Q
T
Q
T
E
P
V
D
L
S
I
Site 10
S85
Q
T
E
P
V
D
L
S
I
N
K
A
R
T
S
Site 11
T91
L
S
I
N
K
A
R
T
S
P
T
A
V
S
S
Site 12
S92
S
I
N
K
A
R
T
S
P
T
A
V
S
S
S
Site 13
T94
N
K
A
R
T
S
P
T
A
V
S
S
S
P
V
Site 14
S97
R
T
S
P
T
A
V
S
S
S
P
V
S
M
T
Site 15
S99
S
P
T
A
V
S
S
S
P
V
S
M
T
A
S
Site 16
S102
A
V
S
S
S
P
V
S
M
T
A
S
A
S
S
Site 17
T104
S
S
S
P
V
S
M
T
A
S
A
S
S
P
S
Site 18
S106
S
P
V
S
M
T
A
S
A
S
S
P
S
S
T
Site 19
S108
V
S
M
T
A
S
A
S
S
P
S
S
T
S
T
Site 20
S109
S
M
T
A
S
A
S
S
P
S
S
T
S
T
S
Site 21
S111
T
A
S
A
S
S
P
S
S
T
S
T
S
S
S
Site 22
S112
A
S
A
S
S
P
S
S
T
S
T
S
S
S
S
Site 23
T113
S
A
S
S
P
S
S
T
S
T
S
S
S
S
S
Site 24
S114
A
S
S
P
S
S
T
S
T
S
S
S
S
S
S
Site 25
T115
S
S
P
S
S
T
S
T
S
S
S
S
S
S
R
Site 26
S116
S
P
S
S
T
S
T
S
S
S
S
S
S
R
L
Site 27
S117
P
S
S
T
S
T
S
S
S
S
S
S
R
L
A
Site 28
S118
S
S
T
S
T
S
S
S
S
S
S
R
L
A
S
Site 29
S119
S
T
S
T
S
S
S
S
S
S
R
L
A
S
S
Site 30
S120
T
S
T
S
S
S
S
S
S
R
L
A
S
S
P
Site 31
S121
S
T
S
S
S
S
S
S
R
L
A
S
S
P
T
Site 32
S125
S
S
S
S
R
L
A
S
S
P
T
V
I
T
S
Site 33
S132
S
S
P
T
V
I
T
S
V
S
S
A
S
S
S
Site 34
S134
P
T
V
I
T
S
V
S
S
A
S
S
S
S
T
Site 35
S138
T
S
V
S
S
A
S
S
S
S
T
V
L
T
P
Site 36
S139
S
V
S
S
A
S
S
S
S
T
V
L
T
P
G
Site 37
S140
V
S
S
A
S
S
S
S
T
V
L
T
P
G
P
Site 38
T141
S
S
A
S
S
S
S
T
V
L
T
P
G
P
L
Site 39
S170
I
I
H
P
V
P
P
S
S
P
M
N
L
Q
S
Site 40
S171
I
H
P
V
P
P
S
S
P
M
N
L
Q
S
N
Site 41
S177
S
S
P
M
N
L
Q
S
N
K
L
S
H
V
H
Site 42
S181
N
L
Q
S
N
K
L
S
H
V
H
R
I
P
V
Site 43
T198
Q
S
V
P
V
V
Y
T
A
V
R
S
P
G
N
Site 44
S202
V
V
Y
T
A
V
R
S
P
G
N
V
N
N
T
Site 45
S232
Q
M
D
P
R
G
L
S
P
R
Q
S
K
S
D
Site 46
S236
R
G
L
S
P
R
Q
S
K
S
D
S
D
D
D
Site 47
S238
L
S
P
R
Q
S
K
S
D
S
D
D
D
D
L
Site 48
S240
P
R
Q
S
K
S
D
S
D
D
D
D
L
P
N
Site 49
T249
D
D
D
L
P
N
V
T
L
D
S
V
N
E
T
Site 50
S252
L
P
N
V
T
L
D
S
V
N
E
T
G
S
T
Site 51
T256
T
L
D
S
V
N
E
T
G
S
T
A
L
S
I
Site 52
S258
D
S
V
N
E
T
G
S
T
A
L
S
I
A
R
Site 53
S262
E
T
G
S
T
A
L
S
I
A
R
A
V
Q
E
Site 54
S273
A
V
Q
E
V
H
P
S
P
V
S
R
V
R
G
Site 55
S276
E
V
H
P
S
P
V
S
R
V
R
G
N
R
M
Site 56
S291
N
N
Q
K
F
P
C
S
I
S
P
F
S
I
E
Site 57
S293
Q
K
F
P
C
S
I
S
P
F
S
I
E
S
T
Site 58
S296
P
C
S
I
S
P
F
S
I
E
S
T
R
R
Q
Site 59
S299
I
S
P
F
S
I
E
S
T
R
R
Q
R
R
S
Site 60
T300
S
P
F
S
I
E
S
T
R
R
Q
R
R
S
E
Site 61
S306
S
T
R
R
Q
R
R
S
E
S
P
D
S
R
K
Site 62
S308
R
R
Q
R
R
S
E
S
P
D
S
R
K
R
R
Site 63
S311
R
R
S
E
S
P
D
S
R
K
R
R
I
H
R
Site 64
Y328
F
E
G
C
N
K
V
Y
T
K
S
S
H
L
K
Site 65
T329
E
G
C
N
K
V
Y
T
K
S
S
H
L
K
A
Site 66
T340
H
L
K
A
H
R
R
T
H
T
G
E
K
P
Y
Site 67
T342
K
A
H
R
R
T
H
T
G
E
K
P
Y
K
C
Site 68
T365
F
A
R
S
D
E
L
T
R
H
Y
R
K
H
T
Site 69
Y368
S
D
E
L
T
R
H
Y
R
K
H
T
G
V
K
Site 70
T372
T
R
H
Y
R
K
H
T
G
V
K
P
F
K
C
Site 71
S385
K
C
A
D
C
D
R
S
F
S
R
S
D
H
L
Site 72
S387
A
D
C
D
R
S
F
S
R
S
D
H
L
A
L
Site 73
S389
C
D
R
S
F
S
R
S
D
H
L
A
L
H
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation