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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRP12
Full Name:
Low-density lipoprotein receptor-related protein 12
Alias:
Suppressor of tumorigenicity 7 protein
Type:
Mass (Da):
94984
Number AA:
859
UniProt ID:
Q9Y561
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
C
R
W
S
T
K
E
S
P
R
W
R
S
A
L
Site 2
S430
N
G
V
C
Y
P
R
S
D
R
C
N
Y
Q
N
Site 3
Y435
P
R
S
D
R
C
N
Y
Q
N
H
C
P
N
G
Site 4
T495
I
V
P
T
R
V
I
T
A
A
V
I
G
S
L
Site 5
S501
I
T
A
A
V
I
G
S
L
I
C
G
L
L
L
Site 6
T515
L
V
I
A
L
G
C
T
C
K
L
Y
S
L
R
Site 7
S528
L
R
M
F
E
R
R
S
F
E
T
Q
L
S
R
Site 8
S534
R
S
F
E
T
Q
L
S
R
V
E
A
E
L
L
Site 9
S548
L
R
R
E
A
P
P
S
Y
G
Q
L
I
A
Q
Site 10
Y549
R
R
E
A
P
P
S
Y
G
Q
L
I
A
Q
G
Site 11
S584
N
L
R
L
A
V
R
S
Q
L
G
F
T
S
V
Site 12
T589
V
R
S
Q
L
G
F
T
S
V
R
L
P
M
A
Site 13
S590
R
S
Q
L
G
F
T
S
V
R
L
P
M
A
G
Site 14
S615
N
F
A
R
S
R
H
S
G
S
L
A
L
V
S
Site 15
S617
A
R
S
R
H
S
G
S
L
A
L
V
S
A
D
Site 16
S631
D
G
D
E
V
V
P
S
Q
S
T
S
R
E
P
Site 17
S633
D
E
V
V
P
S
Q
S
T
S
R
E
P
E
R
Site 18
S635
V
V
P
S
Q
S
T
S
R
E
P
E
R
N
H
Site 19
T643
R
E
P
E
R
N
H
T
H
R
S
L
F
S
V
Site 20
S646
E
R
N
H
T
H
R
S
L
F
S
V
E
S
D
Site 21
S649
H
T
H
R
S
L
F
S
V
E
S
D
D
T
D
Site 22
S652
R
S
L
F
S
V
E
S
D
D
T
D
T
E
N
Site 23
T655
F
S
V
E
S
D
D
T
D
T
E
N
E
R
R
Site 24
T657
V
E
S
D
D
T
D
T
E
N
E
R
R
D
M
Site 25
S694
A
T
V
G
A
C
A
S
S
S
T
Q
S
T
R
Site 26
S695
T
V
G
A
C
A
S
S
S
T
Q
S
T
R
G
Site 27
S696
V
G
A
C
A
S
S
S
T
Q
S
T
R
G
G
Site 28
S699
C
A
S
S
S
T
Q
S
T
R
G
G
H
A
D
Site 29
T700
A
S
S
S
T
Q
S
T
R
G
G
H
A
D
N
Site 30
T712
A
D
N
G
R
D
V
T
S
V
E
P
P
S
V
Site 31
S713
D
N
G
R
D
V
T
S
V
E
P
P
S
V
S
Site 32
S718
V
T
S
V
E
P
P
S
V
S
P
A
R
H
Q
Site 33
S720
S
V
E
P
P
S
V
S
P
A
R
H
Q
L
T
Site 34
T727
S
P
A
R
H
Q
L
T
S
A
L
S
R
M
T
Site 35
S728
P
A
R
H
Q
L
T
S
A
L
S
R
M
T
Q
Site 36
S731
H
Q
L
T
S
A
L
S
R
M
T
Q
G
L
R
Site 37
T734
T
S
A
L
S
R
M
T
Q
G
L
R
W
V
R
Site 38
T743
G
L
R
W
V
R
F
T
L
G
R
S
S
S
L
Site 39
S747
V
R
F
T
L
G
R
S
S
S
L
S
Q
N
Q
Site 40
S748
R
F
T
L
G
R
S
S
S
L
S
Q
N
Q
S
Site 41
S749
F
T
L
G
R
S
S
S
L
S
Q
N
Q
S
P
Site 42
S751
L
G
R
S
S
S
L
S
Q
N
Q
S
P
L
R
Site 43
S755
S
S
L
S
Q
N
Q
S
P
L
R
Q
L
D
N
Site 44
S765
R
Q
L
D
N
G
V
S
G
R
E
D
D
D
D
Site 45
S784
I
P
I
S
D
G
S
S
D
F
D
V
N
D
C
Site 46
S800
R
P
L
L
D
L
A
S
D
Q
G
Q
G
L
R
Site 47
Y810
G
Q
G
L
R
Q
P
Y
N
A
T
N
P
G
V
Site 48
S820
T
N
P
G
V
R
P
S
N
R
D
G
P
C
E
Site 49
T840
H
T
A
Q
I
P
D
T
C
L
E
V
T
L
K
Site 50
T845
P
D
T
C
L
E
V
T
L
K
N
E
T
S
D
Site 51
S851
V
T
L
K
N
E
T
S
D
D
E
A
L
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation