PhosphoNET

           
Protein Info 
   
Short Name:  RIPK3
Full Name:  Receptor-interacting serine/threonine-protein kinase 3
Alias:  RIP-like protein kinase 3;Receptor-interacting protein 3
Type: 
Mass (Da):  56887
Number AA:  518
UniProt ID:  Q9Y572
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S17GAPAPLVSIEELENQ
Site 2T34VGKGGFGTVFRAQHR
Site 3S66REVKAMASLDNEFVL
Site 4S101TKFMENGSLSGLLQS
Site 5S103FMENGSLSGLLQSQC
Site 6S108SLSGLLQSQCPRPWP
Site 7S146LHRDLKPSNVLLDPE
Site 8S164KLADFGLSTFQGGSQ
Site 9T165LADFGLSTFQGGSQS
Site 10S170LSTFQGGSQSGTGSG
Site 11S172TFQGGSQSGTGSGEP
Site 12T174QGGSQSGTGSGEPGG
Site 13S176GSQSGTGSGEPGGTL
Site 14T182GSGEPGGTLGYLAPE
Site 15S199VNVNRKASTASDVYS
Site 16S202NRKASTASDVYSFGI
Site 17S227VELPTEPSLVYEAVC
Site 18Y230PTEPSLVYEAVCNRQ
Site 19S241CNRQNRPSLAELPQA
Site 20T252LPQAGPETPGLEGLK
Site 21S268LMQLCWSSEPKDRPS
Site 22S275SEPKDRPSFQECLPK
Site 23T283FQECLPKTDEVFQMV
Site 24T300NMNAAVSTVKDFLSQ
Site 25S306STVKDFLSQLRSSNR
Site 26S310DFLSQLRSSNRRFSI
Site 27S311FLSQLRSSNRRFSIP
Site 28S316RSSNRRFSIPESGQG
Site 29S320RRFSIPESGQGGTEM
Site 30T325PESGQGGTEMDGFRR
Site 31T333EMDGFRRTIENQHSR
Site 32S339RTIENQHSRNDVMVS
Site 33S359LNLEEPPSSVPKKCP
Site 34S360NLEEPPSSVPKKCPS
Site 35S367SVPKKCPSLTKRSRA
Site 36T369PKKCPSLTKRSRAQE
Site 37S372CPSLTKRSRAQEEQV
Site 38T387PQAWTAGTSSDSMAQ
Site 39S391TAGTSSDSMAQPPQT
Site 40T398SMAQPPQTPETSTFR
Site 41T403PQTPETSTFRNQMPS
Site 42S410TFRNQMPSPTSTGTP
Site 43T412RNQMPSPTSTGTPSP
Site 44S413NQMPSPTSTGTPSPG
Site 45T414QMPSPTSTGTPSPGP
Site 46T416PSPTSTGTPSPGPRG
Site 47S418PTSTGTPSPGPRGNQ
Site 48T438GMNWSCRTPEPNPVT
Site 49T445TPEPNPVTGRPLVNI
Site 50Y465VQVGDNNYLTMQQTT
Site 51T467VGDNNYLTMQQTTAL
Site 52S482PTWGLAPSGKGRGLQ
Site 53S496QHPPPVGSQEGPKDP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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