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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCTD3
Full Name:
BTB/POZ domain-containing protein KCTD3
Alias:
NY-REN-45; Potassium channel tetramerisation domain containing 3; Renal carcinoma antigen NY-REN-45
Type:
Mass (Da):
88984
Number AA:
815
UniProt ID:
Q9Y597
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005249
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S30
N
V
G
G
T
R
F
S
T
S
R
Q
T
L
M
Site 2
T31
V
G
G
T
R
F
S
T
S
R
Q
T
L
M
W
Site 3
S32
G
G
T
R
F
S
T
S
R
Q
T
L
M
W
I
Site 4
T35
R
F
S
T
S
R
Q
T
L
M
W
I
P
D
S
Site 5
S53
S
L
L
S
G
R
I
S
T
L
R
D
E
T
G
Site 6
T54
L
L
S
G
R
I
S
T
L
R
D
E
T
G
A
Site 7
T59
I
S
T
L
R
D
E
T
G
A
I
F
I
D
R
Site 8
T80
P
I
L
N
F
L
R
T
K
E
L
D
L
R
G
Site 9
S89
E
L
D
L
R
G
V
S
I
N
V
L
R
H
E
Site 10
Y100
L
R
H
E
A
E
F
Y
G
I
T
P
L
V
R
Site 11
S119
C
E
E
L
E
R
S
S
C
G
S
V
L
F
H
Site 12
S136
L
P
P
P
G
I
P
S
R
K
I
N
N
T
V
Site 13
T142
P
S
R
K
I
N
N
T
V
R
S
A
D
S
R
Site 14
S148
N
T
V
R
S
A
D
S
R
N
G
L
N
S
T
Site 15
S154
D
S
R
N
G
L
N
S
T
E
G
E
A
R
G
Site 16
S169
N
G
T
Q
P
V
L
S
G
T
G
E
E
T
V
Site 17
Y224
Q
Q
V
F
T
S
P
Y
L
D
W
T
I
E
R
Site 18
T228
T
S
P
Y
L
D
W
T
I
E
R
V
A
L
N
Site 19
S262
E
S
S
I
I
L
W
S
V
Q
D
G
G
S
G
Site 20
S268
W
S
V
Q
D
G
G
S
G
S
E
I
G
V
F
Site 21
S295
G
N
Q
L
V
A
T
S
H
T
G
K
V
G
V
Site 22
Y338
G
C
N
N
G
S
I
Y
Y
I
D
M
Q
K
F
Site 23
Y360
D
L
L
V
T
E
L
Y
H
D
P
S
N
D
A
Site 24
S364
T
E
L
Y
H
D
P
S
N
D
A
I
T
A
L
Site 25
T379
S
V
Y
L
T
P
K
T
S
V
S
G
N
W
I
Site 26
S380
V
Y
L
T
P
K
T
S
V
S
G
N
W
I
E
Site 27
S409
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Site 28
T416
S
G
P
Q
L
F
Q
T
F
T
V
H
R
S
P
Site 29
T418
P
Q
L
F
Q
T
F
T
V
H
R
S
P
V
T
Site 30
S436
L
S
E
K
H
L
V
S
V
C
A
D
N
N
H
Site 31
T448
N
N
H
V
R
T
W
T
V
T
R
F
R
G
M
Site 32
S457
T
R
F
R
G
M
I
S
T
Q
P
G
S
T
P
Site 33
T458
R
F
R
G
M
I
S
T
Q
P
G
S
T
P
L
Site 34
S462
M
I
S
T
Q
P
G
S
T
P
L
A
S
F
K
Site 35
T463
I
S
T
Q
P
G
S
T
P
L
A
S
F
K
I
Site 36
S467
P
G
S
T
P
L
A
S
F
K
I
L
S
L
E
Site 37
S472
L
A
S
F
K
I
L
S
L
E
E
T
E
S
H
Site 38
T476
K
I
L
S
L
E
E
T
E
S
H
G
S
Y
S
Site 39
S478
L
S
L
E
E
T
E
S
H
G
S
Y
S
S
G
Site 40
S481
E
E
T
E
S
H
G
S
Y
S
S
G
N
D
I
Site 41
Y482
E
T
E
S
H
G
S
Y
S
S
G
N
D
I
G
Site 42
S484
E
S
H
G
S
Y
S
S
G
N
D
I
G
P
F
Site 43
S516
N
K
L
F
V
R
L
S
S
T
G
K
R
I
C
Site 44
S517
K
L
F
V
R
L
S
S
T
G
K
R
I
C
E
Site 45
S535
V
D
C
T
T
I
S
S
F
T
V
R
E
C
E
Site 46
T537
C
T
T
I
S
S
F
T
V
R
E
C
E
G
S
Site 47
S544
T
V
R
E
C
E
G
S
S
R
M
G
S
R
P
Site 48
S549
E
G
S
S
R
M
G
S
R
P
R
R
Y
L
F
Site 49
Y554
M
G
S
R
P
R
R
Y
L
F
T
G
H
T
N
Site 50
T557
R
P
R
R
Y
L
F
T
G
H
T
N
G
S
I
Site 51
S579
A
M
D
M
V
N
K
S
E
D
K
D
V
G
G
Site 52
T588
D
K
D
V
G
G
P
T
E
E
E
L
L
K
L
Site 53
S602
L
L
D
Q
C
D
L
S
T
S
R
C
A
T
P
Site 54
T603
L
D
Q
C
D
L
S
T
S
R
C
A
T
P
N
Site 55
S604
D
Q
C
D
L
S
T
S
R
C
A
T
P
N
I
Site 56
T608
L
S
T
S
R
C
A
T
P
N
I
S
P
A
T
Site 57
S612
R
C
A
T
P
N
I
S
P
A
T
S
V
V
Q
Site 58
S616
P
N
I
S
P
A
T
S
V
V
Q
H
S
H
L
Site 59
S621
A
T
S
V
V
Q
H
S
H
L
R
E
S
N
S
Site 60
S626
Q
H
S
H
L
R
E
S
N
S
S
L
Q
L
Q
Site 61
S628
S
H
L
R
E
S
N
S
S
L
Q
L
Q
H
H
Site 62
S629
H
L
R
E
S
N
S
S
L
Q
L
Q
H
H
D
Site 63
T637
L
Q
L
Q
H
H
D
T
T
H
E
A
A
T
Y
Site 64
T638
Q
L
Q
H
H
D
T
T
H
E
A
A
T
Y
G
Site 65
Y644
T
T
H
E
A
A
T
Y
G
S
M
R
P
Y
R
Site 66
S646
H
E
A
A
T
Y
G
S
M
R
P
Y
R
E
S
Site 67
Y650
T
Y
G
S
M
R
P
Y
R
E
S
P
L
L
A
Site 68
S653
S
M
R
P
Y
R
E
S
P
L
L
A
R
A
R
Site 69
T662
L
L
A
R
A
R
R
T
E
S
F
H
S
Y
R
Site 70
S664
A
R
A
R
R
T
E
S
F
H
S
Y
R
D
F
Site 71
S667
R
R
T
E
S
F
H
S
Y
R
D
F
Q
T
I
Site 72
Y668
R
T
E
S
F
H
S
Y
R
D
F
Q
T
I
N
Site 73
S707
A
T
G
E
C
N
I
S
E
R
K
S
P
G
V
Site 74
S711
C
N
I
S
E
R
K
S
P
G
V
E
I
K
S
Site 75
S718
S
P
G
V
E
I
K
S
L
R
E
L
D
S
G
Site 76
S724
K
S
L
R
E
L
D
S
G
L
E
V
H
K
I
Site 77
S736
H
K
I
A
E
G
F
S
E
S
K
K
R
S
S
Site 78
S738
I
A
E
G
F
S
E
S
K
K
R
S
S
E
D
Site 79
S742
F
S
E
S
K
K
R
S
S
E
D
E
N
E
N
Site 80
S743
S
E
S
K
K
R
S
S
E
D
E
N
E
N
K
Site 81
Y772
L
G
R
K
K
V
P
Y
L
A
S
S
P
S
T
Site 82
S775
K
K
V
P
Y
L
A
S
S
P
S
T
S
D
G
Site 83
S776
K
V
P
Y
L
A
S
S
P
S
T
S
D
G
G
Site 84
S778
P
Y
L
A
S
S
P
S
T
S
D
G
G
T
D
Site 85
T779
Y
L
A
S
S
P
S
T
S
D
G
G
T
D
S
Site 86
S780
L
A
S
S
P
S
T
S
D
G
G
T
D
S
P
Site 87
T784
P
S
T
S
D
G
G
T
D
S
P
G
T
A
S
Site 88
S786
T
S
D
G
G
T
D
S
P
G
T
A
S
P
S
Site 89
T789
G
G
T
D
S
P
G
T
A
S
P
S
P
T
K
Site 90
S791
T
D
S
P
G
T
A
S
P
S
P
T
K
T
T
Site 91
S793
S
P
G
T
A
S
P
S
P
T
K
T
T
P
S
Site 92
T795
G
T
A
S
P
S
P
T
K
T
T
P
S
P
R
Site 93
T797
A
S
P
S
P
T
K
T
T
P
S
P
R
H
K
Site 94
T798
S
P
S
P
T
K
T
T
P
S
P
R
H
K
K
Site 95
S800
S
P
T
K
T
T
P
S
P
R
H
K
K
S
D
Site 96
S806
P
S
P
R
H
K
K
S
D
S
S
G
Q
E
Y
Site 97
S808
P
R
H
K
K
S
D
S
S
G
Q
E
Y
S
L
Site 98
S809
R
H
K
K
S
D
S
S
G
Q
E
Y
S
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation