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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TNPO3
Full Name:
Transportin-3
Alias:
Importin-12;Transportin-SR
Type:
Mass (Da):
104203
Number AA:
923
UniProt ID:
Q9Y5L0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
Y
Q
A
V
Q
A
L
Y
H
D
P
D
P
S
G
Site 2
S25
L
Y
H
D
P
D
P
S
G
K
E
R
A
S
F
Site 3
S31
P
S
G
K
E
R
A
S
F
W
L
G
E
L
Q
Site 4
Y61
R
Q
D
V
E
S
C
Y
F
A
A
Q
T
M
K
Site 5
S74
M
K
M
K
I
Q
T
S
F
Y
E
L
P
T
D
Site 6
Y76
M
K
I
Q
T
S
F
Y
E
L
P
T
D
S
H
Site 7
T80
T
S
F
Y
E
L
P
T
D
S
H
A
S
L
R
Site 8
S82
F
Y
E
L
P
T
D
S
H
A
S
L
R
D
S
Site 9
S85
L
P
T
D
S
H
A
S
L
R
D
S
L
L
T
Site 10
S89
S
H
A
S
L
R
D
S
L
L
T
H
I
Q
N
Site 11
T92
S
L
R
D
S
L
L
T
H
I
Q
N
L
K
D
Site 12
T128
S
W
K
G
C
V
Q
T
L
V
E
K
Y
S
N
Site 13
S134
Q
T
L
V
E
K
Y
S
N
D
V
T
S
L
P
Site 14
T138
E
K
Y
S
N
D
V
T
S
L
P
F
L
L
E
Site 15
S156
V
L
P
E
E
V
H
S
R
S
L
R
I
G
A
Site 16
S158
P
E
E
V
H
S
R
S
L
R
I
G
A
N
R
Site 17
T167
R
I
G
A
N
R
R
T
E
I
I
E
D
L
A
Site 18
T193
T
C
V
E
K
A
G
T
D
E
K
M
L
M
K
Site 19
T237
E
V
L
Q
Q
D
K
T
S
S
N
L
H
E
A
Site 20
S239
L
Q
Q
D
K
T
S
S
N
L
H
E
A
A
S
Site 21
Y347
E
I
S
F
N
F
W
Y
R
L
G
E
H
L
Y
Site 22
Y354
Y
R
L
G
E
H
L
Y
K
T
N
D
E
V
I
Site 23
T356
L
G
E
H
L
Y
K
T
N
D
E
V
I
H
G
Site 24
S404
G
E
F
R
M
R
V
S
D
L
V
K
D
L
I
Site 25
Y424
M
E
C
F
A
Q
L
Y
S
T
L
K
E
G
N
Site 26
S450
I
M
A
A
I
A
K
S
V
D
P
E
N
N
P
Site 27
T458
V
D
P
E
N
N
P
T
L
V
E
V
L
E
G
Site 28
T475
R
L
P
E
T
V
H
T
A
V
R
Y
T
S
I
Site 29
S597
M
A
L
K
K
L
L
S
Q
E
P
S
N
G
I
Site 30
S601
K
L
L
S
Q
E
P
S
N
G
I
S
S
D
P
Site 31
S605
Q
E
P
S
N
G
I
S
S
D
P
T
V
F
L
Site 32
S606
E
P
S
N
G
I
S
S
D
P
T
V
F
L
D
Site 33
T609
N
G
I
S
S
D
P
T
V
F
L
D
R
L
A
Site 34
T631
P
I
V
E
N
G
Q
T
H
P
C
Q
K
V
I
Site 35
S646
Q
E
I
W
P
V
L
S
E
T
L
N
K
H
R
Site 36
Y711
G
S
I
L
V
D
E
Y
G
M
E
E
G
C
R
Site 37
T748
G
L
Q
N
H
P
D
T
V
D
D
L
F
R
L
Site 38
T757
D
D
L
F
R
L
A
T
R
F
I
Q
R
S
P
Site 39
S763
A
T
R
F
I
Q
R
S
P
V
T
L
L
R
S
Site 40
T805
F
L
R
D
L
I
H
T
G
V
A
N
D
H
E
Site 41
S875
F
C
R
W
L
E
N
S
L
K
G
L
P
K
E
Site 42
T891
T
V
G
A
V
T
V
T
H
K
Q
L
T
D
F
Site 43
T896
T
V
T
H
K
Q
L
T
D
F
H
K
Q
V
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation