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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DMRT1
Full Name:
Doublesex- and mab-3-related transcription factor 1
Alias:
DM domain expressed in testis protein 1
Type:
Mass (Da):
39473
Number AA:
373
UniProt ID:
Q9Y5R6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
N
D
E
A
F
S
K
P
S
T
P
S
E
Site 2
T12
E
A
F
S
K
P
S
T
P
S
E
A
P
H
A
Site 3
S14
F
S
K
P
S
T
P
S
E
A
P
H
A
P
G
Site 4
S45
L
V
G
A
A
S
G
S
S
A
G
G
S
S
R
Site 5
S46
V
G
A
A
S
G
S
S
A
G
G
S
S
R
G
Site 6
S50
S
G
S
S
A
G
G
S
S
R
G
G
G
S
G
Site 7
S51
G
S
S
A
G
G
S
S
R
G
G
G
S
G
S
Site 8
S56
G
S
S
R
G
G
G
S
G
S
G
A
S
D
L
Site 9
S58
S
R
G
G
G
S
G
S
G
A
S
D
L
G
A
Site 10
S61
G
G
S
G
S
G
A
S
D
L
G
A
G
S
K
Site 11
S67
A
S
D
L
G
A
G
S
K
K
S
P
R
L
P
Site 12
S70
L
G
A
G
S
K
K
S
P
R
L
P
K
C
A
Site 13
Y84
A
R
C
R
N
H
G
Y
A
S
P
L
K
G
H
Site 14
S86
C
R
N
H
G
Y
A
S
P
L
K
G
H
K
R
Site 15
S134
Q
E
E
E
L
G
I
S
H
P
I
P
L
P
S
Site 16
S154
V
K
R
E
N
N
G
S
N
P
C
L
M
T
E
Site 17
T160
G
S
N
P
C
L
M
T
E
C
S
G
T
S
Q
Site 18
S163
P
C
L
M
T
E
C
S
G
T
S
Q
P
P
P
Site 19
T165
L
M
T
E
C
S
G
T
S
Q
P
P
P
A
S
Site 20
S166
M
T
E
C
S
G
T
S
Q
P
P
P
A
S
V
Site 21
S172
T
S
Q
P
P
P
A
S
V
P
T
T
A
A
S
Site 22
T176
P
P
A
S
V
P
T
T
A
A
S
E
G
R
M
Site 23
T200
S
R
G
H
V
E
N
T
P
D
L
V
S
D
S
Site 24
S205
E
N
T
P
D
L
V
S
D
S
T
Y
Y
S
S
Site 25
S207
T
P
D
L
V
S
D
S
T
Y
Y
S
S
F
Y
Site 26
T208
P
D
L
V
S
D
S
T
Y
Y
S
S
F
Y
Q
Site 27
Y209
D
L
V
S
D
S
T
Y
Y
S
S
F
Y
Q
P
Site 28
S211
V
S
D
S
T
Y
Y
S
S
F
Y
Q
P
S
L
Site 29
S212
S
D
S
T
Y
Y
S
S
F
Y
Q
P
S
L
F
Site 30
Y214
S
T
Y
Y
S
S
F
Y
Q
P
S
L
F
P
Y
Site 31
Y221
Y
Q
P
S
L
F
P
Y
Y
N
N
L
Y
N
C
Site 32
Y222
Q
P
S
L
F
P
Y
Y
N
N
L
Y
N
C
P
Site 33
Y226
F
P
Y
Y
N
N
L
Y
N
C
P
Q
Y
S
M
Site 34
S251
V
G
N
P
L
G
G
S
P
V
K
N
S
L
R
Site 35
S256
G
G
S
P
V
K
N
S
L
R
G
L
P
G
P
Site 36
Y264
L
R
G
L
P
G
P
Y
V
P
G
Q
T
G
N
Site 37
Y288
R
H
A
M
S
S
Q
Y
R
M
H
S
Y
Y
P
Site 38
S292
S
S
Q
Y
R
M
H
S
Y
Y
P
P
P
S
Y
Site 39
Y293
S
Q
Y
R
M
H
S
Y
Y
P
P
P
S
Y
L
Site 40
Y294
Q
Y
R
M
H
S
Y
Y
P
P
P
S
Y
L
G
Site 41
S298
H
S
Y
Y
P
P
P
S
Y
L
G
Q
S
V
P
Site 42
Y299
S
Y
Y
P
P
P
S
Y
L
G
Q
S
V
P
Q
Site 43
S303
P
P
S
Y
L
G
Q
S
V
P
Q
F
F
T
F
Site 44
T309
Q
S
V
P
Q
F
F
T
F
E
D
A
P
S
Y
Site 45
S315
F
T
F
E
D
A
P
S
Y
P
E
A
R
A
S
Site 46
Y316
T
F
E
D
A
P
S
Y
P
E
A
R
A
S
V
Site 47
S322
S
Y
P
E
A
R
A
S
V
F
S
P
P
S
S
Site 48
S325
E
A
R
A
S
V
F
S
P
P
S
S
Q
D
S
Site 49
S328
A
S
V
F
S
P
P
S
S
Q
D
S
G
L
V
Site 50
S329
S
V
F
S
P
P
S
S
Q
D
S
G
L
V
S
Site 51
S332
S
P
P
S
S
Q
D
S
G
L
V
S
L
S
S
Site 52
S336
S
Q
D
S
G
L
V
S
L
S
S
S
S
P
I
Site 53
S338
D
S
G
L
V
S
L
S
S
S
S
P
I
S
N
Site 54
S339
S
G
L
V
S
L
S
S
S
S
P
I
S
N
K
Site 55
S340
G
L
V
S
L
S
S
S
S
P
I
S
N
K
S
Site 56
S341
L
V
S
L
S
S
S
S
P
I
S
N
K
S
T
Site 57
S344
L
S
S
S
S
P
I
S
N
K
S
T
K
A
V
Site 58
S347
S
S
P
I
S
N
K
S
T
K
A
V
L
E
C
Site 59
T348
S
P
I
S
N
K
S
T
K
A
V
L
E
C
E
Site 60
S358
V
L
E
C
E
P
A
S
E
P
S
S
F
T
V
Site 61
S362
E
P
A
S
E
P
S
S
F
T
V
T
P
V
I
Site 62
T364
A
S
E
P
S
S
F
T
V
T
P
V
I
E
E
Site 63
T366
E
P
S
S
F
T
V
T
P
V
I
E
E
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation