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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX14
Full Name:
Sorting nexin-14
Alias:
RGS-PX2; Sorting nexin 14
Type:
Unknown function
Mass (Da):
110182
Number AA:
946
UniProt ID:
Q9Y5W7
International Prot ID:
IPI00216696
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y84
N
I
F
F
T
I
K
Y
K
P
K
Q
L
G
L
Site 2
S115
K
C
K
R
H
R
P
S
L
L
L
E
N
Y
Q
Site 3
Y121
P
S
L
L
L
E
N
Y
Q
P
W
L
D
L
K
Site 4
S130
P
W
L
D
L
K
I
S
S
K
V
D
A
S
L
Site 5
S131
W
L
D
L
K
I
S
S
K
V
D
A
S
L
S
Site 6
Y153
E
N
F
V
Y
P
W
Y
R
D
V
T
D
D
E
Site 7
S161
R
D
V
T
D
D
E
S
F
V
D
E
L
R
I
Site 8
S188
I
H
K
V
D
I
P
S
I
I
T
K
K
L
L
Site 9
S236
E
L
H
V
A
L
R
S
R
R
D
E
L
H
Y
Site 10
Y243
S
R
R
D
E
L
H
Y
L
R
K
L
T
E
L
Site 11
S265
P
K
A
T
D
C
R
S
L
T
L
L
I
R
E
Site 12
S303
L
I
I
F
I
D
D
S
P
P
E
K
A
T
E
Site 13
T309
D
S
P
P
E
K
A
T
E
P
A
S
P
L
V
Site 14
S313
E
K
A
T
E
P
A
S
P
L
V
P
F
L
Q
Site 15
S331
E
P
R
N
K
K
P
S
V
L
K
L
E
L
K
Site 16
T368
H
V
L
Q
F
C
L
T
V
E
E
F
N
D
R
Site 17
S382
R
I
L
R
P
E
L
S
N
D
E
M
L
S
L
Site 18
S388
L
S
N
D
E
M
L
S
L
H
E
E
L
Q
K
Site 19
Y397
H
E
E
L
Q
K
I
Y
K
T
Y
C
L
D
E
Site 20
T399
E
L
Q
K
I
Y
K
T
Y
C
L
D
E
S
I
Site 21
Y464
M
F
C
H
S
D
E
Y
F
R
Q
L
L
R
G
Site 22
S474
Q
L
L
R
G
A
E
S
P
T
R
N
S
K
L
Site 23
S479
A
E
S
P
T
R
N
S
K
L
N
R
G
S
L
Site 24
S485
N
S
K
L
N
R
G
S
L
S
L
D
D
F
R
Site 25
S487
K
L
N
R
G
S
L
S
L
D
D
F
R
N
T
Site 26
T494
S
L
D
D
F
R
N
T
Q
K
R
G
E
S
F
Site 27
S500
N
T
Q
K
R
G
E
S
F
G
I
S
R
I
G
Site 28
S504
R
G
E
S
F
G
I
S
R
I
G
S
K
I
K
Site 29
S516
K
I
K
G
V
F
K
S
T
T
M
E
G
A
M
Site 30
T518
K
G
V
F
K
S
T
T
M
E
G
A
M
L
P
Site 31
Y527
E
G
A
M
L
P
N
Y
G
V
A
E
G
E
D
Site 32
S554
D
S
P
V
E
A
V
S
T
P
N
T
P
R
N
Site 33
T555
S
P
V
E
A
V
S
T
P
N
T
P
R
N
L
Site 34
T558
E
A
V
S
T
P
N
T
P
R
N
L
A
A
W
Site 35
Y571
A
W
K
I
S
I
P
Y
V
D
F
F
E
D
P
Site 36
S579
V
D
F
F
E
D
P
S
S
E
R
K
E
K
K
Site 37
S580
D
F
F
E
D
P
S
S
E
R
K
E
K
K
E
Site 38
Y614
E
P
E
H
W
S
V
Y
R
R
Y
L
E
F
Y
Site 39
Y617
H
W
S
V
Y
R
R
Y
L
E
F
Y
V
L
E
Site 40
Y621
Y
R
R
Y
L
E
F
Y
V
L
E
S
K
L
T
Site 41
T628
Y
V
L
E
S
K
L
T
E
F
H
G
A
F
P
Site 42
S641
F
P
D
A
Q
L
P
S
K
R
I
I
G
P
K
Site 43
Y650
R
I
I
G
P
K
N
Y
E
F
L
K
S
K
R
Site 44
S655
K
N
Y
E
F
L
K
S
K
R
E
E
F
Q
E
Site 45
Y663
K
R
E
E
F
Q
E
Y
L
Q
K
L
L
Q
H
Site 46
S674
L
L
Q
H
P
E
L
S
N
S
Q
L
L
A
D
Site 47
S676
Q
H
P
E
L
S
N
S
Q
L
L
A
D
F
L
Site 48
S684
Q
L
L
A
D
F
L
S
P
N
G
G
E
T
Q
Site 49
S708
N
L
G
K
I
I
K
S
V
P
G
K
L
M
K
Site 50
S734
N
F
I
N
S
C
E
S
P
K
P
K
P
S
R
Site 51
S740
E
S
P
K
P
K
P
S
R
P
E
L
T
I
L
Site 52
S748
R
P
E
L
T
I
L
S
P
T
S
E
N
N
K
Site 53
S751
L
T
I
L
S
P
T
S
E
N
N
K
K
L
F
Site 54
Y780
E
R
K
Q
N
Q
N
Y
F
M
E
V
M
T
V
Site 55
T786
N
Y
F
M
E
V
M
T
V
E
G
V
Y
D
Y
Site 56
Y826
F
K
N
T
L
E
M
Y
T
D
Y
Y
L
Q
C
Site 57
Y829
T
L
E
M
Y
T
D
Y
Y
L
Q
C
K
L
E
Site 58
Y830
L
E
M
Y
T
D
Y
Y
L
Q
C
K
L
E
Q
Site 59
T860
D
A
I
F
C
E
N
T
E
P
R
S
L
Q
D
Site 60
S864
C
E
N
T
E
P
R
S
L
Q
D
K
Q
K
G
Site 61
T875
K
Q
K
G
A
K
Q
T
F
E
E
M
M
N
Y
Site 62
Y897
C
I
G
E
E
T
K
Y
E
S
I
R
L
L
F
Site 63
S899
G
E
E
T
K
Y
E
S
I
R
L
L
F
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation