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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX13
Full Name:
Sorting nexin-13
Alias:
KIAA0713; RGS domain- and PHOX domain-containing protein; RGS-PX1; Sorting nexin 13
Type:
Mass (Da):
112189
Number AA:
968
UniProt ID:
Q9Y5W8
International Prot ID:
IPI00396267
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0009968
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T53
V
T
L
L
F
G
K
T
N
S
E
K
Y
L
E
Site 2
S55
L
L
F
G
K
T
N
S
E
K
Y
L
E
Q
C
Site 3
Y58
G
K
T
N
S
E
K
Y
L
E
Q
C
E
H
S
Site 4
S65
Y
L
E
Q
C
E
H
S
F
L
P
P
T
S
P
Site 5
T70
E
H
S
F
L
P
P
T
S
P
G
V
P
K
C
Site 6
S71
H
S
F
L
P
P
T
S
P
G
V
P
K
C
L
Site 7
T95
I
K
I
D
R
R
L
T
G
A
N
I
I
D
E
Site 8
Y115
I
Q
F
S
L
R
D
Y
V
Q
Y
W
Y
Y
T
Site 9
Y118
S
L
R
D
Y
V
Q
Y
W
Y
Y
T
L
S
D
Site 10
Y120
R
D
Y
V
Q
Y
W
Y
Y
T
L
S
D
D
E
Site 11
S128
Y
T
L
S
D
D
E
S
F
L
L
E
I
R
Q
Site 12
Y156
K
E
I
D
W
Q
P
Y
F
T
T
R
I
V
D
Site 13
T167
R
I
V
D
D
F
G
T
H
L
R
V
F
R
K
Site 14
S216
C
R
D
L
V
C
T
S
P
K
D
E
E
G
F
Site 15
S267
L
P
L
I
N
Q
L
S
D
P
D
Y
I
N
Q
Site 16
Y271
N
Q
L
S
D
P
D
Y
I
N
Q
Y
V
I
W
Site 17
Y287
I
R
D
S
N
C
N
Y
E
A
F
M
N
I
I
Site 18
Y316
K
A
A
E
E
L
Q
Y
L
R
S
L
D
T
A
Site 19
S319
E
E
L
Q
Y
L
R
S
L
D
T
A
G
D
D
Site 20
S353
S
R
I
Q
R
L
Q
S
G
K
E
I
N
T
V
Site 21
T359
Q
S
G
K
E
I
N
T
V
K
L
A
A
N
F
Site 22
Y390
A
L
Q
F
F
M
D
Y
M
Q
Q
T
G
G
Q
Site 23
T412
T
V
E
G
Y
R
V
T
A
Q
Q
Q
L
E
V
Site 24
S422
Q
Q
L
E
V
L
L
S
R
Q
R
D
G
K
H
Site 25
Y449
A
V
G
I
Y
E
Q
Y
L
S
E
K
A
S
P
Site 26
S451
G
I
Y
E
Q
Y
L
S
E
K
A
S
P
R
V
Site 27
S455
Q
Y
L
S
E
K
A
S
P
R
V
T
V
D
D
Site 28
T459
E
K
A
S
P
R
V
T
V
D
D
Y
L
V
A
Site 29
T471
L
V
A
K
L
A
D
T
L
N
H
E
D
P
T
Site 30
T478
T
L
N
H
E
D
P
T
P
E
I
F
D
D
I
Site 31
Y490
D
D
I
Q
R
K
V
Y
E
L
M
L
R
D
E
Site 32
Y500
M
L
R
D
E
R
F
Y
P
S
F
R
Q
N
A
Site 33
S502
R
D
E
R
F
Y
P
S
F
R
Q
N
A
L
Y
Site 34
S523
L
D
M
L
K
D
P
S
F
R
G
S
D
D
G
Site 35
S527
K
D
P
S
F
R
G
S
D
D
G
D
G
E
S
Site 36
S534
S
D
D
G
D
G
E
S
F
N
G
S
P
T
G
Site 37
S538
D
G
E
S
F
N
G
S
P
T
G
S
I
N
L
Site 38
T540
E
S
F
N
G
S
P
T
G
S
I
N
L
S
L
Site 39
S542
F
N
G
S
P
T
G
S
I
N
L
S
L
D
D
Site 40
S546
P
T
G
S
I
N
L
S
L
D
D
L
S
N
V
Site 41
S551
N
L
S
L
D
D
L
S
N
V
S
S
D
D
S
Site 42
S554
L
D
D
L
S
N
V
S
S
D
D
S
V
Q
L
Site 43
S555
D
D
L
S
N
V
S
S
D
D
S
V
Q
L
H
Site 44
S558
S
N
V
S
S
D
D
S
V
Q
L
H
A
Y
I
Site 45
Y564
D
S
V
Q
L
H
A
Y
I
S
D
T
V
Y
A
Site 46
T568
L
H
A
Y
I
S
D
T
V
Y
A
D
Y
D
P
Site 47
Y570
A
Y
I
S
D
T
V
Y
A
D
Y
D
P
Y
A
Site 48
Y573
S
D
T
V
Y
A
D
Y
D
P
Y
A
V
A
G
Site 49
Y592
H
G
K
T
Y
A
L
Y
A
I
T
V
H
R
R
Site 50
T595
T
Y
A
L
Y
A
I
T
V
H
R
R
N
L
N
Site 51
Y610
S
E
E
M
W
K
T
Y
R
R
Y
S
D
F
H
Site 52
T624
H
D
F
H
M
R
I
T
E
Q
F
E
S
L
S
Site 53
S629
R
I
T
E
Q
F
E
S
L
S
S
I
L
K
L
Site 54
S632
E
Q
F
E
S
L
S
S
I
L
K
L
P
G
K
Site 55
T641
L
K
L
P
G
K
K
T
F
N
N
M
D
R
D
Site 56
Y660
R
K
K
D
L
N
A
Y
L
Q
L
L
L
A
P
Site 57
Y679
A
S
P
A
L
A
H
Y
V
Y
D
F
L
E
N
Site 58
Y681
P
A
L
A
H
Y
V
Y
D
F
L
E
N
K
A
Site 59
Y689
D
F
L
E
N
K
A
Y
S
K
G
K
G
D
F
Site 60
T702
D
F
A
R
K
M
D
T
F
V
N
P
L
R
N
Site 61
S710
F
V
N
P
L
R
N
S
M
R
N
V
S
N
A
Site 62
S715
R
N
S
M
R
N
V
S
N
A
V
K
S
L
P
Site 63
S720
N
V
S
N
A
V
K
S
L
P
D
S
L
A
E
Site 64
S724
A
V
K
S
L
P
D
S
L
A
E
G
M
T
K
Site 65
S740
S
D
N
M
G
K
M
S
E
R
L
G
Q
D
I
Site 66
S750
L
G
Q
D
I
K
Q
S
F
F
K
V
P
P
L
Site 67
T761
V
P
P
L
I
P
K
T
D
S
D
P
E
H
R
Site 68
S763
P
L
I
P
K
T
D
S
D
P
E
H
R
R
V
Site 69
S771
D
P
E
H
R
R
V
S
A
Q
L
D
D
N
V
Site 70
T819
L
Q
Q
L
I
R
A
T
Y
G
D
T
I
N
R
Site 71
Y820
Q
Q
L
I
R
A
T
Y
G
D
T
I
N
R
K
Site 72
T823
I
R
A
T
Y
G
D
T
I
N
R
K
I
V
D
Site 73
S837
D
H
V
D
W
M
T
S
P
E
Q
V
A
D
S
Site 74
S844
S
P
E
Q
V
A
D
S
V
K
R
F
R
D
A
Site 75
S868
A
V
P
C
R
D
K
S
I
R
M
R
T
R
V
Site 76
T873
D
K
S
I
R
M
R
T
R
V
A
G
K
T
K
Site 77
T897
K
H
I
I
G
A
E
T
T
R
K
G
I
L
R
Site 78
Y934
L
E
T
L
F
P
Q
Y
K
F
R
E
L
F
N
Site 79
Y953
R
S
K
Q
M
Q
K
Y
K
Q
K
L
Q
T
T
Site 80
T960
Y
K
Q
K
L
Q
T
T
Q
A
P
S
L
Q
K
Site 81
S964
L
Q
T
T
Q
A
P
S
L
Q
K
R
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation