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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX5
Full Name:
Sorting nexin-5
Alias:
Sorting nexin 5
Type:
Vesicle protein
Mass (Da):
46816
Number AA:
404
UniProt ID:
Q9Y5X3
International Prot ID:
IPI00295209
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005543
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0007154
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
Q
Q
Q
E
E
D
R
S
K
L
R
S
V
S
V
Site 2
S20
E
D
R
S
K
L
R
S
V
S
V
D
L
N
V
Site 3
S22
R
S
K
L
R
S
V
S
V
D
L
N
V
D
P
Site 4
S30
V
D
L
N
V
D
P
S
L
Q
I
D
I
P
D
Site 5
S40
I
D
I
P
D
A
L
S
E
R
D
K
V
K
F
Site 6
T53
K
F
T
V
H
T
K
T
T
L
P
T
F
Q
S
Site 7
T57
H
T
K
T
T
L
P
T
F
Q
S
P
E
F
S
Site 8
S60
T
T
L
P
T
F
Q
S
P
E
F
S
V
T
R
Site 9
S64
T
F
Q
S
P
E
F
S
V
T
R
Q
H
E
D
Site 10
T66
Q
S
P
E
F
S
V
T
R
Q
H
E
D
F
V
Site 11
S115
K
L
G
E
G
E
G
S
M
T
K
E
E
F
A
Site 12
T117
G
E
G
E
G
S
M
T
K
E
E
F
A
K
M
Site 13
Y132
K
Q
E
L
E
A
E
Y
L
A
V
F
K
K
T
Site 14
S142
V
F
K
K
T
V
S
S
H
E
V
F
L
Q
R
Site 15
S151
E
V
F
L
Q
R
L
S
S
H
P
V
L
S
K
Site 16
S152
V
F
L
Q
R
L
S
S
H
P
V
L
S
K
D
Site 17
S157
L
S
S
H
P
V
L
S
K
D
R
N
F
H
V
Site 18
Y168
N
F
H
V
F
L
E
Y
D
Q
D
L
S
V
R
Site 19
S173
L
E
Y
D
Q
D
L
S
V
R
R
K
N
T
K
Site 20
T179
L
S
V
R
R
K
N
T
K
E
M
F
G
G
F
Site 21
T200
S
A
D
E
V
L
F
T
G
V
K
E
V
D
D
Site 22
Y219
E
K
N
F
L
I
N
Y
Y
N
R
I
K
D
S
Site 23
Y220
K
N
F
L
I
N
Y
Y
N
R
I
K
D
S
C
Site 24
S236
K
A
D
K
M
T
R
S
H
K
N
V
A
D
D
Site 25
Y244
H
K
N
V
A
D
D
Y
I
H
T
A
A
C
L
Site 26
S284
R
K
V
E
G
R
V
S
S
D
E
D
L
K
L
Site 27
S285
K
V
E
G
R
V
S
S
D
E
D
L
K
L
T
Site 28
Y298
L
T
E
L
L
R
Y
Y
M
L
N
I
E
A
A
Site 29
Y310
E
A
A
K
D
L
L
Y
R
R
T
K
A
L
I
Site 30
T313
K
D
L
L
Y
R
R
T
K
A
L
I
D
Y
E
Site 31
Y319
R
T
K
A
L
I
D
Y
E
N
S
N
K
A
L
Site 32
S333
L
D
K
A
R
L
K
S
K
D
V
K
L
A
E
Site 33
S354
C
Q
K
F
E
Q
L
S
E
S
A
K
E
E
L
Site 34
S356
K
F
E
Q
L
S
E
S
A
K
E
E
L
I
N
Site 35
S380
R
K
N
L
I
E
M
S
E
L
E
I
K
H
A
Site 36
S392
K
H
A
R
N
N
V
S
L
L
Q
S
C
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation