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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIPG
Full Name:
Endothelial lipase
Alias:
Endothelial cell-derived lipase
Type:
Mass (Da):
56795
Number AA:
500
UniProt ID:
Q9Y5X9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T43
H
K
P
K
A
T
Q
T
E
V
K
P
S
V
R
Site 2
S48
T
Q
T
E
V
K
P
S
V
R
F
N
L
R
T
Site 3
T55
S
V
R
F
N
L
R
T
S
K
D
P
E
H
E
Site 4
S56
V
R
F
N
L
R
T
S
K
D
P
E
H
E
G
Site 5
Y65
D
P
E
H
E
G
C
Y
L
S
V
G
H
S
Q
Site 6
S67
E
H
E
G
C
Y
L
S
V
G
H
S
Q
P
L
Site 7
S71
C
Y
L
S
V
G
H
S
Q
P
L
E
D
C
S
Site 8
S78
S
Q
P
L
E
D
C
S
F
N
M
T
A
K
T
Site 9
S107
N
W
L
H
K
L
V
S
A
L
H
T
R
E
K
Site 10
T111
K
L
V
S
A
L
H
T
R
E
K
D
A
N
V
Site 11
Y131
L
P
L
A
H
Q
L
Y
T
D
A
V
N
N
T
Site 12
S159
L
Q
E
K
D
D
F
S
L
G
N
V
H
L
I
Site 13
T190
K
G
T
V
G
R
I
T
G
L
D
P
A
G
P
Site 14
S209
A
D
I
H
K
R
L
S
P
D
D
A
D
F
V
Site 15
Y242
P
V
G
H
I
D
I
Y
P
N
G
G
D
F
Q
Site 16
S284
A
V
H
L
F
V
D
S
L
V
N
Q
D
K
P
Site 17
S292
L
V
N
Q
D
K
P
S
F
A
F
Q
C
T
D
Site 18
S332
K
M
R
N
K
R
N
S
K
M
Y
L
K
T
R
Site 19
Y335
N
K
R
N
S
K
M
Y
L
K
T
R
A
G
M
Site 20
T338
N
S
K
M
Y
L
K
T
R
A
G
M
P
F
R
Site 21
Y358
M
K
I
H
V
F
S
Y
K
N
M
G
E
I
E
Site 22
T367
N
M
G
E
I
E
P
T
F
Y
V
T
L
Y
G
Site 23
Y369
G
E
I
E
P
T
F
Y
V
T
L
Y
G
T
N
Site 24
Y373
P
T
F
Y
V
T
L
Y
G
T
N
A
D
S
Q
Site 25
S379
L
Y
G
T
N
A
D
S
Q
T
L
P
L
E
I
Site 26
T381
G
T
N
A
D
S
Q
T
L
P
L
E
I
V
E
Site 27
T395
E
R
I
E
Q
N
A
T
N
T
F
L
V
Y
T
Site 28
T397
I
E
Q
N
A
T
N
T
F
L
V
Y
T
E
E
Site 29
T415
D
L
L
K
I
Q
L
T
W
E
G
A
S
Q
S
Site 30
Y424
E
G
A
S
Q
S
W
Y
N
L
W
K
E
F
R
Site 31
Y433
L
W
K
E
F
R
S
Y
L
S
Q
P
R
N
P
Site 32
S435
K
E
F
R
S
Y
L
S
Q
P
R
N
P
G
R
Site 33
S453
I
R
R
I
R
V
K
S
G
E
T
Q
R
K
L
Site 34
T461
G
E
T
Q
R
K
L
T
F
C
T
E
D
P
E
Site 35
T464
Q
R
K
L
T
F
C
T
E
D
P
E
N
T
S
Site 36
S473
D
P
E
N
T
S
I
S
P
G
R
E
L
W
F
Site 37
T493
G
W
R
M
K
N
E
T
S
P
T
V
E
L
P
Site 38
S494
W
R
M
K
N
E
T
S
P
T
V
E
L
P
_
Site 39
T496
M
K
N
E
T
S
P
T
V
E
L
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation