KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RAD54B
Full Name:
DNA repair and recombination protein RAD54B
Alias:
RAD54 homolog B
Type:
Mass (Da):
102967
Number AA:
910
UniProt ID:
Q9Y620
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S4
_
_
_
_
M
R
R
S
A
A
P
S
Q
L
Q
Site 2
S8
M
R
R
S
A
A
P
S
Q
L
Q
G
N
S
F
Site 3
S14
P
S
Q
L
Q
G
N
S
F
K
K
P
K
F
I
Site 4
S26
K
F
I
P
P
G
R
S
N
P
G
L
N
E
E
Site 5
T52
E
G
V
A
I
N
N
T
F
L
P
S
Q
N
D
Site 6
S64
Q
N
D
L
R
I
C
S
L
N
L
P
S
E
E
Site 7
S72
L
N
L
P
S
E
E
S
T
R
E
I
N
N
R
Site 8
Y86
R
D
N
C
S
G
K
Y
C
F
E
A
P
T
L
Site 9
T101
A
T
L
D
P
P
H
T
V
H
S
A
P
K
E
Site 10
S112
A
P
K
E
V
A
V
S
K
E
Q
E
E
K
S
Site 11
S119
S
K
E
Q
E
E
K
S
D
S
L
V
K
Y
F
Site 12
S121
E
Q
E
E
K
S
D
S
L
V
K
Y
F
S
V
Site 13
Y125
K
S
D
S
L
V
K
Y
F
S
V
V
W
C
K
Site 14
Y170
D
I
G
R
G
I
G
Y
K
F
K
E
L
E
K
Site 15
T183
E
K
I
E
E
G
Q
T
L
M
I
C
G
K
E
Site 16
S203
V
I
S
P
D
D
F
S
S
G
R
C
F
Q
L
Site 17
S204
I
S
P
D
D
F
S
S
G
R
C
F
Q
L
G
Site 18
S214
C
F
Q
L
G
G
G
S
T
A
I
S
H
S
S
Site 19
T215
F
Q
L
G
G
G
S
T
A
I
S
H
S
S
Q
Site 20
S218
G
G
G
S
T
A
I
S
H
S
S
Q
V
A
R
Site 21
S221
S
T
A
I
S
H
S
S
Q
V
A
R
K
C
F
Site 22
S234
C
F
S
N
P
F
K
S
V
C
K
P
S
S
K
Site 23
S240
K
S
V
C
K
P
S
S
K
E
N
R
Q
N
D
Site 24
Y258
C
K
P
R
H
D
P
Y
T
P
N
S
L
V
M
Site 25
T259
K
P
R
H
D
P
Y
T
P
N
S
L
V
M
P
Site 26
S262
H
D
P
Y
T
P
N
S
L
V
M
P
R
P
D
Site 27
Y294
V
I
D
P
Y
L
V
Y
H
L
R
P
H
Q
K
Site 28
S365
T
L
I
V
T
P
G
S
L
V
N
N
W
K
K
Site 29
T387
S
E
R
I
K
I
F
T
V
D
Q
D
H
K
V
Site 30
S409
F
Y
S
V
L
I
I
S
Y
E
M
L
L
R
S
Site 31
S416
S
Y
E
M
L
L
R
S
L
D
Q
I
K
N
I
Site 32
S439
E
G
H
R
L
K
N
S
A
I
K
T
T
T
A
Site 33
S449
K
T
T
T
A
L
I
S
L
S
C
E
K
R
I
Site 34
T461
K
R
I
I
L
T
G
T
P
I
Q
N
D
L
Q
Site 35
S484
V
N
P
G
I
L
G
S
L
S
S
Y
R
K
I
Site 36
S486
P
G
I
L
G
S
L
S
S
Y
R
K
I
Y
E
Site 37
S487
G
I
L
G
S
L
S
S
Y
R
K
I
Y
E
E
Site 38
Y488
I
L
G
S
L
S
S
Y
R
K
I
Y
E
E
P
Site 39
Y492
L
S
S
Y
R
K
I
Y
E
E
P
I
I
L
S
Site 40
S499
Y
E
E
P
I
I
L
S
R
E
P
S
A
S
E
Site 41
S503
I
I
L
S
R
E
P
S
A
S
E
E
E
K
E
Site 42
S505
L
S
R
E
P
S
A
S
E
E
E
K
E
L
G
Site 43
T531
G
L
F
I
L
R
R
T
Q
E
I
I
N
K
Y
Site 44
Y538
T
Q
E
I
I
N
K
Y
L
P
P
K
I
E
N
Site 45
Y559
G
A
L
Q
I
E
L
Y
R
K
L
L
N
S
Q
Site 46
S601
H
P
C
L
L
F
N
S
I
K
E
K
E
C
S
Site 47
S608
S
I
K
E
K
E
C
S
S
T
C
D
K
N
E
Site 48
S609
I
K
E
K
E
C
S
S
T
C
D
K
N
E
E
Site 49
T610
K
E
K
E
C
S
S
T
C
D
K
N
E
E
K
Site 50
S618
C
D
K
N
E
E
K
S
L
Y
K
G
L
L
S
Site 51
Y620
K
N
E
E
K
S
L
Y
K
G
L
L
S
V
F
Site 52
S648
S
G
K
L
Q
V
L
S
K
L
L
A
V
I
H
Site 53
Y685
E
V
C
K
R
H
G
Y
A
Y
T
R
L
D
G
Site 54
Y687
C
K
R
H
G
Y
A
Y
T
R
L
D
G
Q
T
Site 55
T694
Y
T
R
L
D
G
Q
T
P
I
S
Q
R
Q
Q
Site 56
S697
L
D
G
Q
T
P
I
S
Q
R
Q
Q
I
V
D
Site 57
S708
Q
I
V
D
G
F
N
S
Q
H
S
S
F
F
I
Site 58
Y738
G
G
S
H
L
I
L
Y
D
I
D
W
N
P
A
Site 59
Y761
V
W
R
D
G
Q
K
Y
P
V
H
I
Y
R
L
Site 60
T770
V
H
I
Y
R
L
L
T
T
G
T
I
E
E
K
Site 61
Y779
G
T
I
E
E
K
I
Y
Q
R
Q
I
S
K
Q
Site 62
S784
K
I
Y
Q
R
Q
I
S
K
Q
G
L
C
G
A
Site 63
T796
C
G
A
V
V
D
L
T
K
T
S
E
H
I
Q
Site 64
S805
T
S
E
H
I
Q
F
S
V
E
E
L
K
N
L
Site 65
T814
E
E
L
K
N
L
F
T
L
H
E
S
S
D
C
Site 66
S819
L
F
T
L
H
E
S
S
D
C
V
T
H
D
L
Site 67
T823
H
E
S
S
D
C
V
T
H
D
L
L
D
C
E
Site 68
T838
C
T
G
E
E
V
H
T
G
D
S
L
E
K
F
Site 69
S841
E
E
V
H
T
G
D
S
L
E
K
F
I
V
S
Site 70
S860
L
G
P
H
H
Q
K
S
N
S
L
K
P
L
S
Site 71
S862
P
H
H
Q
K
S
N
S
L
K
P
L
S
M
S
Site 72
S867
S
N
S
L
K
P
L
S
M
S
Q
L
K
Q
W
Site 73
S869
S
L
K
P
L
S
M
S
Q
L
K
Q
W
K
H
Site 74
T885
S
G
D
H
L
N
L
T
D
P
F
L
E
R
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation