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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPC6
Full Name:
Glypican-6
Alias:
Type:
Mass (Da):
62736
Number AA:
555
UniProt ID:
Q9Y625
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
P
S
W
I
G
A
V
I
L
Site 2
S29
G
A
D
V
K
A
R
S
C
G
E
V
R
Q
A
Site 3
Y37
C
G
E
V
R
Q
A
Y
G
A
K
G
F
S
L
Site 4
S43
A
Y
G
A
K
G
F
S
L
A
D
I
P
Y
Q
Site 5
Y49
F
S
L
A
D
I
P
Y
Q
E
I
A
G
E
H
Site 6
S76
T
E
M
E
D
K
L
S
Q
Q
S
K
L
E
F
Site 7
T96
E
T
S
H
F
V
R
T
T
F
V
S
R
H
K
Site 8
T97
T
S
H
F
V
R
T
T
F
V
S
R
H
K
K
Site 9
S100
F
V
R
T
T
F
V
S
R
H
K
K
F
D
E
Site 10
S119
L
L
E
N
A
E
K
S
L
N
D
M
F
V
R
Site 11
Y132
V
R
T
Y
G
M
L
Y
M
Q
N
S
E
V
F
Site 12
T144
E
V
F
Q
D
L
F
T
E
L
K
R
Y
Y
T
Site 13
Y149
L
F
T
E
L
K
R
Y
Y
T
G
G
N
V
N
Site 14
Y150
F
T
E
L
K
R
Y
Y
T
G
G
N
V
N
L
Site 15
T151
T
E
L
K
R
Y
Y
T
G
G
N
V
N
L
E
Site 16
Y180
F
Q
L
I
N
P
Q
Y
H
F
S
E
D
Y
L
Site 17
Y186
Q
Y
H
F
S
E
D
Y
L
E
C
V
S
K
Y
Site 18
T226
R
T
F
V
Q
G
L
T
V
G
R
E
V
A
N
Site 19
S236
R
E
V
A
N
R
V
S
K
V
S
P
T
P
G
Site 20
S239
A
N
R
V
S
K
V
S
P
T
P
G
C
I
R
Site 21
Y269
T
V
R
P
C
N
N
Y
C
L
N
V
M
K
G
Site 22
S310
E
G
P
F
N
I
E
S
V
M
D
P
I
D
V
Site 23
S352
K
P
A
P
A
L
R
S
A
R
S
A
P
E
N
Site 24
T362
S
A
P
E
N
F
N
T
R
F
R
P
Y
N
P
Site 25
Y367
F
N
T
R
F
R
P
Y
N
P
E
E
R
P
T
Site 26
T374
Y
N
P
E
E
R
P
T
T
A
A
G
T
S
L
Site 27
T375
N
P
E
E
R
P
T
T
A
A
G
T
S
L
D
Site 28
T386
T
S
L
D
R
L
V
T
D
I
K
E
K
L
K
Site 29
S395
I
K
E
K
L
K
L
S
K
K
V
W
S
A
L
Site 30
S411
Y
T
I
C
K
D
E
S
V
T
A
G
T
S
N
Site 31
S417
E
S
V
T
A
G
T
S
N
E
E
E
C
W
N
Site 32
Y431
N
G
H
S
K
A
R
Y
L
P
E
I
M
N
D
Site 33
T441
E
I
M
N
D
G
L
T
N
Q
I
N
N
P
E
Site 34
T454
P
E
V
D
V
D
I
T
R
P
D
T
F
I
R
Site 35
T458
V
D
I
T
R
P
D
T
F
I
R
Q
Q
I
M
Site 36
T488
N
D
V
N
F
Q
D
T
S
D
E
S
S
G
S
Site 37
S489
D
V
N
F
Q
D
T
S
D
E
S
S
G
S
G
Site 38
S492
F
Q
D
T
S
D
E
S
S
G
S
G
S
G
S
Site 39
S493
Q
D
T
S
D
E
S
S
G
S
G
S
G
S
G
Site 40
S495
T
S
D
E
S
S
G
S
G
S
G
S
G
C
M
Site 41
S497
D
E
S
S
G
S
G
S
G
S
G
C
M
D
D
Site 42
S499
S
S
G
S
G
S
G
S
G
C
M
D
D
V
C
Site 43
T515
T
E
F
E
F
V
T
T
E
A
P
A
V
D
P
Site 44
S529
P
D
R
R
E
V
D
S
S
A
A
Q
R
G
H
Site 45
S530
D
R
R
E
V
D
S
S
A
A
Q
R
G
H
S
Site 46
S537
S
A
A
Q
R
G
H
S
L
L
S
W
S
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation