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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PGCP
Full Name:
Plasma glutamate carboxypeptidase
Alias:
Aminopeptidase; Blood plasma glutamate carboxypeptidase precursor; EC 3.4.17.-; Pgcp; Prostate-specific membrane antigen (psma)
Type:
Enzyme - Carboxypeptidase
Mass (Da):
51888
Number AA:
472
UniProt ID:
Q9Y646
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005615
Uniprot
OncoNet
Molecular Function:
GO:0004181
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006518
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S42
E
I
K
E
E
I
A
S
C
G
D
V
A
K
A
Site 2
Y56
A
I
I
N
L
A
V
Y
G
K
A
Q
N
R
S
Site 3
S63
Y
G
K
A
Q
N
R
S
Y
E
R
L
A
L
L
Site 4
Y64
G
K
A
Q
N
R
S
Y
E
R
L
A
L
L
V
Site 5
S79
D
T
V
G
P
R
L
S
G
S
K
N
L
E
K
Site 6
S155
A
E
V
L
V
V
T
S
F
D
E
L
Q
R
R
Site 7
S164
D
E
L
Q
R
R
A
S
E
A
R
G
K
I
V
Site 8
Y173
A
R
G
K
I
V
V
Y
N
Q
P
Y
I
N
Y
Site 9
Y177
I
V
V
Y
N
Q
P
Y
I
N
Y
S
R
T
V
Site 10
Y180
Y
N
Q
P
Y
I
N
Y
S
R
T
V
Q
Y
R
Site 11
T183
P
Y
I
N
Y
S
R
T
V
Q
Y
R
T
Q
G
Site 12
S211
I
R
S
V
A
S
F
S
I
Y
S
P
H
T
G
Site 13
S214
V
A
S
F
S
I
Y
S
P
H
T
G
I
Q
E
Site 14
Y222
P
H
T
G
I
Q
E
Y
Q
D
G
V
P
K
I
Site 15
S243
V
E
D
A
E
M
M
S
R
M
A
S
H
G
I
Site 16
T262
Q
L
K
M
G
A
K
T
Y
P
D
T
D
S
F
Site 17
Y263
L
K
M
G
A
K
T
Y
P
D
T
D
S
F
N
Site 18
T266
G
A
K
T
Y
P
D
T
D
S
F
N
T
V
A
Site 19
S268
K
T
Y
P
D
T
D
S
F
N
T
V
A
E
I
Site 20
T271
P
D
T
D
S
F
N
T
V
A
E
I
T
G
S
Site 21
S278
T
V
A
E
I
T
G
S
K
Y
P
E
Q
V
V
Site 22
S288
P
E
Q
V
V
L
V
S
G
H
L
D
S
W
D
Site 23
S293
L
V
S
G
H
L
D
S
W
D
V
G
Q
G
A
Site 24
Y346
G
G
V
G
A
F
Q
Y
Y
Q
L
H
K
V
N
Site 25
Y347
G
V
G
A
F
Q
Y
Y
Q
L
H
K
V
N
I
Site 26
Y357
H
K
V
N
I
S
N
Y
S
L
V
M
E
S
D
Site 27
S358
K
V
N
I
S
N
Y
S
L
V
M
E
S
D
A
Site 28
S378
T
G
L
Q
F
T
G
S
E
K
A
R
A
I
M
Site 29
T398
L
L
Q
P
L
N
I
T
Q
V
L
S
H
G
E
Site 30
S421
Q
A
G
V
P
G
A
S
L
L
D
D
L
Y
K
Site 31
Y427
A
S
L
L
D
D
L
Y
K
Y
F
F
F
H
H
Site 32
Y429
L
L
D
D
L
Y
K
Y
F
F
F
H
H
S
H
Site 33
T439
F
H
H
S
H
G
D
T
M
T
V
M
D
P
K
Site 34
T441
H
S
H
G
D
T
M
T
V
M
D
P
K
Q
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation