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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HS3ST4
Full Name:
Heparan sulfate glucosamine 3-O-sulfotransferase 4
Alias:
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
Type:
Mass (Da):
49826
Number AA:
456
UniProt ID:
Q9Y661
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
A
P
P
P
P
G
A
S
A
K
G
P
P
A
R
Site 2
S68
F
P
L
A
L
Q
E
S
P
G
A
A
A
E
P
Site 3
S78
A
A
A
E
P
P
P
S
P
P
P
P
S
L
L
Site 4
S83
P
P
S
P
P
P
P
S
L
L
P
T
P
V
R
Site 5
S95
P
V
R
L
G
A
P
S
Q
P
P
A
P
P
P
Site 6
S107
P
P
P
L
D
N
A
S
H
G
E
P
P
E
P
Site 7
T123
E
Q
P
A
A
P
G
T
D
G
W
G
L
P
S
Site 8
T142
A
R
D
A
W
L
R
T
P
L
A
P
S
E
M
Site 9
S164
P
E
R
E
A
Q
E
S
S
T
T
D
E
D
L
Site 10
T167
E
A
Q
E
S
S
T
T
D
E
D
L
A
G
R
Site 11
S180
G
R
R
A
A
N
G
S
S
E
R
G
G
A
V
Site 12
S181
R
R
A
A
N
G
S
S
E
R
G
G
A
V
S
Site 13
S188
S
E
R
G
G
A
V
S
T
P
D
Y
G
E
K
Site 14
T189
E
R
G
G
A
V
S
T
P
D
Y
G
E
K
K
Site 15
Y192
G
A
V
S
T
P
D
Y
G
E
K
K
L
P
Q
Site 16
Y237
P
H
F
F
D
R
N
Y
E
K
G
L
E
W
Y
Site 17
Y244
Y
E
K
G
L
E
W
Y
R
N
V
M
P
K
T
Site 18
T251
Y
R
N
V
M
P
K
T
L
D
G
Q
I
T
M
Site 19
T257
K
T
L
D
G
Q
I
T
M
E
K
T
P
S
Y
Site 20
T261
G
Q
I
T
M
E
K
T
P
S
Y
F
V
T
N
Site 21
S263
I
T
M
E
K
T
P
S
Y
F
V
T
N
E
A
Site 22
Y264
T
M
E
K
T
P
S
Y
F
V
T
N
E
A
P
Site 23
T267
K
T
P
S
Y
F
V
T
N
E
A
P
K
R
I
Site 24
S276
E
A
P
K
R
I
H
S
M
A
K
D
I
K
L
Site 25
S296
N
P
V
T
R
A
I
S
D
Y
T
Q
T
L
S
Site 26
Y298
V
T
R
A
I
S
D
Y
T
Q
T
L
S
K
K
Site 27
T299
T
R
A
I
S
D
Y
T
Q
T
L
S
K
K
P
Site 28
T301
A
I
S
D
Y
T
Q
T
L
S
K
K
P
E
I
Site 29
S303
S
D
Y
T
Q
T
L
S
K
K
P
E
I
P
T
Site 30
T310
S
K
K
P
E
I
P
T
F
E
V
L
A
F
K
Site 31
Y346
H
L
E
N
W
L
Q
Y
F
P
L
S
Q
I
L
Site 32
T382
L
G
L
K
R
V
V
T
K
K
H
F
Y
F
N
Site 33
Y387
V
V
T
K
K
H
F
Y
F
N
K
T
K
G
F
Site 34
S404
L
K
K
P
E
D
S
S
A
P
R
C
L
G
K
Site 35
S412
A
P
R
C
L
G
K
S
K
G
R
T
H
P
R
Site 36
T416
L
G
K
S
K
G
R
T
H
P
R
I
D
P
D
Site 37
Y432
I
H
R
L
R
K
F
Y
K
P
F
N
L
M
F
Site 38
Y440
K
P
F
N
L
M
F
Y
Q
M
T
G
Q
D
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation