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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GMEB1
Full Name:
Glucocorticoid modulatory element-binding protein 1
Alias:
DNA-binding protein P96pif; GMEB-1; P96PIF; parvovirus initiation factor p96; PIF p96; PIF96
Type:
Nuclear receptor co-regulator
Mass (Da):
62591
Number AA:
573
UniProt ID:
Q9Y692
International Prot ID:
IPI00008601
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003713
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
E
N
P
E
D
T
K
T
Q
V
I
L
Q
L
Q
Site 2
Y51
L
F
I
D
G
H
F
Y
N
R
I
Y
E
A
G
Site 3
Y55
G
H
F
Y
N
R
I
Y
E
A
G
S
E
N
N
Site 4
T63
E
A
G
S
E
N
N
T
A
V
V
A
V
E
T
Site 5
T82
K
I
E
E
G
I
D
T
G
T
I
E
A
N
E
Site 6
T84
E
E
G
I
D
T
G
T
I
E
A
N
E
D
M
Site 7
Y95
N
E
D
M
E
I
A
Y
P
I
T
C
G
E
S
Site 8
S129
K
F
N
D
Q
L
I
S
P
K
H
F
V
H
L
Site 9
Y168
D
S
G
Q
I
D
F
Y
Q
H
D
K
V
C
S
Site 10
T181
C
S
N
T
C
R
S
T
K
F
D
L
L
I
S
Site 11
S200
P
V
P
G
Q
Q
T
S
V
V
Q
T
P
T
S
Site 12
T204
Q
Q
T
S
V
V
Q
T
P
T
S
A
D
G
S
Site 13
S207
S
V
V
Q
T
P
T
S
A
D
G
S
I
T
Q
Site 14
S218
S
I
T
Q
I
A
I
S
E
E
S
M
E
E
A
Site 15
S249
E
E
G
V
K
K
D
S
E
E
I
S
E
D
T
Site 16
S253
K
K
D
S
E
E
I
S
E
D
T
L
M
F
W
Site 17
T256
S
E
E
I
S
E
D
T
L
M
F
W
K
G
I
Site 18
T316
H
T
F
G
L
M
D
T
V
K
K
V
L
D
N
Site 19
Y337
Q
G
E
E
Q
F
L
Y
T
L
T
D
L
E
R
Site 20
S360
G
Q
D
H
R
L
K
S
Q
T
V
Q
N
V
V
Site 21
T362
D
H
R
L
K
S
Q
T
V
Q
N
V
V
L
M
Site 22
S372
N
V
V
L
M
P
V
S
T
P
K
P
P
K
R
Site 23
T373
V
V
L
M
P
V
S
T
P
K
P
P
K
R
P
Site 24
S387
P
R
L
Q
R
P
A
S
T
T
V
L
S
P
S
Site 25
T388
R
L
Q
R
P
A
S
T
T
V
L
S
P
S
P
Site 26
T389
L
Q
R
P
A
S
T
T
V
L
S
P
S
P
P
Site 27
S392
P
A
S
T
T
V
L
S
P
S
P
P
V
Q
Q
Site 28
S394
S
T
T
V
L
S
P
S
P
P
V
Q
Q
P
Q
Site 29
T426
M
G
N
I
P
V
A
T
L
S
Q
G
S
S
P
Site 30
T435
S
Q
G
S
S
P
V
T
V
H
T
L
P
S
G
Site 31
T438
S
S
P
V
T
V
H
T
L
P
S
G
P
Q
L
Site 32
T450
P
Q
L
F
R
Y
A
T
V
V
S
S
A
K
S
Site 33
S453
F
R
Y
A
T
V
V
S
S
A
K
S
S
S
P
Site 34
S454
R
Y
A
T
V
V
S
S
A
K
S
S
S
P
D
Site 35
S457
T
V
V
S
S
A
K
S
S
S
P
D
T
V
T
Site 36
S458
V
V
S
S
A
K
S
S
S
P
D
T
V
T
I
Site 37
S459
V
S
S
A
K
S
S
S
P
D
T
V
T
I
H
Site 38
T462
A
K
S
S
S
P
D
T
V
T
I
H
P
S
S
Site 39
T464
S
S
S
P
D
T
V
T
I
H
P
S
S
S
L
Site 40
S483
S
T
A
M
Q
D
G
S
T
L
G
N
M
T
T
Site 41
T484
T
A
M
Q
D
G
S
T
L
G
N
M
T
T
M
Site 42
T489
G
S
T
L
G
N
M
T
T
M
V
S
P
V
E
Site 43
S513
S
A
I
Q
A
V
E
S
T
S
E
D
G
Q
T
Site 44
S515
I
Q
A
V
E
S
T
S
E
D
G
Q
T
I
I
Site 45
T520
S
T
S
E
D
G
Q
T
I
I
E
I
D
P
A
Site 46
T535
P
D
P
E
A
E
D
T
E
G
K
A
V
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation