KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NFS1
Full Name:
Cysteine desulfurase, mitochondrial
Alias:
Type:
Mass (Da):
50177
Number AA:
457
UniProt ID:
Q9Y697
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005759
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0031071
GO:0042803
GO:0030170
PhosphoSite+
KinaseNET
Biological Process:
GO:0006777
GO:0006534
GO:0018283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
R
R
A
A
V
A
V
T
A
A
P
G
P
K
P
Site 2
T26
G
P
K
P
A
A
P
T
R
G
L
R
L
R
V
Site 3
S40
V
G
D
R
A
P
Q
S
A
V
P
A
D
T
A
Site 4
Y60
G
P
V
L
R
P
L
Y
M
D
V
Q
A
T
T
Site 5
T67
Y
M
D
V
Q
A
T
T
P
L
D
P
R
V
L
Site 6
Y84
M
L
P
Y
L
I
N
Y
Y
G
N
P
H
S
R
Site 7
Y85
L
P
Y
L
I
N
Y
Y
G
N
P
H
S
R
T
Site 8
T92
Y
G
N
P
H
S
R
T
H
A
Y
G
W
E
S
Site 9
Y95
P
H
S
R
T
H
A
Y
G
W
E
S
E
A
A
Site 10
S112
R
A
R
Q
Q
V
A
S
L
I
G
A
D
P
R
Site 11
T124
D
P
R
E
I
I
F
T
S
G
A
T
E
S
N
Site 12
S125
P
R
E
I
I
F
T
S
G
A
T
E
S
N
N
Site 13
Y142
I
K
G
V
A
R
F
Y
R
S
R
K
K
H
L
Site 14
T154
K
H
L
I
T
T
Q
T
E
H
K
C
V
L
D
Site 15
S162
E
H
K
C
V
L
D
S
C
R
S
L
E
A
E
Site 16
S165
C
V
L
D
S
C
R
S
L
E
A
E
G
F
Q
Site 17
Y175
A
E
G
F
Q
V
T
Y
L
P
V
Q
K
S
G
Site 18
S181
T
Y
L
P
V
Q
K
S
G
I
I
D
L
K
E
Site 19
S201
Q
P
D
T
S
L
V
S
V
M
T
V
N
N
E
Site 20
S223
A
E
I
G
R
I
C
S
S
R
K
V
Y
F
H
Site 21
Y228
I
C
S
S
R
K
V
Y
F
H
T
D
A
A
Q
Site 22
S255
K
I
D
L
M
S
I
S
G
H
K
I
Y
G
P
Site 23
Y260
S
I
S
G
H
K
I
Y
G
P
K
G
V
G
A
Site 24
Y269
P
K
G
V
G
A
I
Y
I
R
R
R
P
R
V
Site 25
S283
V
R
V
E
A
L
Q
S
G
G
G
Q
E
R
G
Site 26
T295
E
R
G
M
R
S
G
T
V
P
T
P
L
V
V
Site 27
Y317
V
A
Q
Q
E
M
E
Y
D
H
K
R
I
S
K
Site 28
S323
E
Y
D
H
K
R
I
S
K
L
S
E
R
L
I
Site 29
S326
H
K
R
I
S
K
L
S
E
R
L
I
Q
N
I
Site 30
Y350
N
G
D
P
K
H
H
Y
P
G
C
I
N
L
S
Site 31
S383
S
S
G
S
A
C
T
S
A
S
L
E
P
S
Y
Site 32
S404
T
D
E
D
L
A
H
S
S
I
R
F
G
I
G
Site 33
S405
D
E
D
L
A
H
S
S
I
R
F
G
I
G
R
Site 34
T414
R
F
G
I
G
R
F
T
T
E
E
E
V
D
Y
Site 35
T415
F
G
I
G
R
F
T
T
E
E
E
V
D
Y
T
Site 36
Y421
T
T
E
E
E
V
D
Y
T
V
E
K
C
I
Q
Site 37
T422
T
E
E
E
V
D
Y
T
V
E
K
C
I
Q
H
Site 38
S437
V
K
R
L
R
E
M
S
P
L
W
E
M
V
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation