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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAF6L
Full Name:
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L
Alias:
PAF65A; PAF65-alpha; PCAF-associated factor 65 alpha; TAF6-like RNA polymerase II; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L: PCAF-associated factor 65 alpha
Type:
Transcription initiation complex
Mass (Da):
67814
Number AA:
622
UniProt ID:
Q9Y6J9
International Prot ID:
IPI00007957
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030914
GO:0000118
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003702
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0006338
GO:0043966
GO:0051090
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
F
V
E
I
P
R
E
S
V
R
L
M
A
E
S
Site 2
S23
S
V
R
L
M
A
E
S
T
G
L
E
L
S
D
Site 3
Y42
L
L
A
E
D
V
C
Y
R
L
R
E
A
T
Q
Site 4
T48
C
Y
R
L
R
E
A
T
Q
N
S
S
Q
F
M
Site 5
S52
R
E
A
T
Q
N
S
S
Q
F
M
K
H
T
K
Site 6
T58
S
S
Q
F
M
K
H
T
K
R
R
K
L
T
V
Site 7
T64
H
T
K
R
R
K
L
T
V
E
D
F
N
R
A
Site 8
S76
N
R
A
L
R
W
S
S
V
E
A
V
C
G
Y
Site 9
S85
E
A
V
C
G
Y
G
S
Q
E
A
L
P
M
R
Site 10
Y100
P
A
R
E
G
E
L
Y
F
P
E
D
R
E
V
Site 11
S132
T
A
V
R
V
H
V
S
Y
L
D
G
K
G
N
Site 12
Y133
A
V
R
V
H
V
S
Y
L
D
G
K
G
N
L
Site 13
S145
G
N
L
A
P
Q
G
S
V
P
S
A
V
S
S
Site 14
S148
A
P
Q
G
S
V
P
S
A
V
S
S
L
T
D
Site 15
T154
P
S
A
V
S
S
L
T
D
D
L
L
K
Y
Y
Site 16
Y160
L
T
D
D
L
L
K
Y
Y
H
Q
V
T
R
A
Site 17
Y161
T
D
D
L
L
K
Y
Y
H
Q
V
T
R
A
V
Site 18
S187
L
Q
D
L
Q
T
N
S
K
I
G
A
L
L
P
Site 19
S205
Y
V
V
S
G
V
K
S
V
S
H
D
L
E
Q
Site 20
S222
R
L
L
Q
V
A
R
S
L
F
R
N
P
H
L
Site 21
T262
N
P
L
N
D
H
W
T
L
R
D
G
A
A
L
Site 22
Y327
K
A
V
E
R
V
L
Y
P
H
L
S
T
Y
W
Site 23
Y333
L
Y
P
H
L
S
T
Y
W
T
N
L
Q
A
V
Site 24
T335
P
H
L
S
T
Y
W
T
N
L
Q
A
V
L
D
Site 25
Y344
L
Q
A
V
L
D
D
Y
S
V
S
N
A
Q
V
Site 26
S345
Q
A
V
L
D
D
Y
S
V
S
N
A
Q
V
K
Site 27
S399
L
D
D
L
P
W
D
S
L
L
F
Q
E
S
S
Site 28
S405
D
S
L
L
F
Q
E
S
S
S
G
G
G
A
E
Site 29
S406
S
L
L
F
Q
E
S
S
S
G
G
G
A
E
P
Site 30
S414
S
G
G
G
A
E
P
S
F
G
S
G
L
P
L
Site 31
S417
G
A
E
P
S
F
G
S
G
L
P
L
P
P
G
Site 32
S432
G
A
G
P
E
D
P
S
L
S
V
T
L
A
D
Site 33
S434
G
P
E
D
P
S
L
S
V
T
L
A
D
I
Y
Site 34
T436
E
D
P
S
L
S
V
T
L
A
D
I
Y
R
E
Site 35
T458
S
L
A
T
R
F
G
T
G
Q
P
A
P
T
A
Site 36
T464
G
T
G
Q
P
A
P
T
A
P
R
P
P
G
D
Site 37
S481
E
P
A
A
A
P
D
S
V
R
K
M
P
Q
L
Site 38
T489
V
R
K
M
P
Q
L
T
A
S
A
I
V
S
P
Site 39
S491
K
M
P
Q
L
T
A
S
A
I
V
S
P
H
G
Site 40
S495
L
T
A
S
A
I
V
S
P
H
G
D
E
S
P
Site 41
S501
V
S
P
H
G
D
E
S
P
R
G
S
G
G
G
Site 42
S505
G
D
E
S
P
R
G
S
G
G
G
G
P
A
S
Site 43
S512
S
G
G
G
G
P
A
S
A
S
G
P
A
A
S
Site 44
S514
G
G
G
P
A
S
A
S
G
P
A
A
S
E
S
Site 45
S519
S
A
S
G
P
A
A
S
E
S
R
P
L
P
R
Site 46
S521
S
G
P
A
A
S
E
S
R
P
L
P
R
V
H
Site 47
T541
P
R
Q
Q
G
P
G
T
G
T
R
D
V
F
Q
Site 48
T580
C
R
G
R
L
F
Q
T
A
F
P
A
P
Y
G
Site 49
S589
F
P
A
P
Y
G
P
S
P
A
S
R
Y
V
Q
Site 50
S592
P
Y
G
P
S
P
A
S
R
Y
V
Q
K
L
P
Site 51
Y594
G
P
S
P
A
S
R
Y
V
Q
K
L
P
M
I
Site 52
S605
L
P
M
I
G
R
T
S
R
P
A
R
R
W
A
Site 53
S614
P
A
R
R
W
A
L
S
D
Y
S
L
Y
L
P
Site 54
Y616
R
R
W
A
L
S
D
Y
S
L
Y
L
P
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation