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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLCO1B1
Full Name:
Solute carrier organic anion transporter family member 1B1
Alias:
Liver-specific organic anion transporter 1;OATP-C;Sodium-independent organic anion-transporting polypeptide 2;Solute carrier family 21 member 6
Type:
Mass (Da):
76449
Number AA:
691
UniProt ID:
Q9Y6L6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
K
T
A
E
A
Q
P
S
E
N
K
K
T
R
Y
Site 2
T21
Q
P
S
E
N
K
K
T
R
Y
C
N
G
L
K
Site 3
Y23
S
E
N
K
K
T
R
Y
C
N
G
L
K
M
F
Site 4
S63
E
R
R
F
E
I
S
S
S
L
V
G
F
I
D
Site 5
S89
V
F
V
S
Y
F
G
S
K
L
H
R
P
K
L
Site 6
Y120
L
P
H
F
F
M
G
Y
Y
R
Y
S
K
E
T
Site 7
Y121
P
H
F
F
M
G
Y
Y
R
Y
S
K
E
T
N
Site 8
T127
Y
Y
R
Y
S
K
E
T
N
I
N
S
S
E
N
Site 9
S131
S
K
E
T
N
I
N
S
S
E
N
S
T
S
T
Site 10
S135
N
I
N
S
S
E
N
S
T
S
T
L
S
T
C
Site 11
T136
I
N
S
S
E
N
S
T
S
T
L
S
T
C
L
Site 12
S137
N
S
S
E
N
S
T
S
T
L
S
T
C
L
I
Site 13
T138
S
S
E
N
S
T
S
T
L
S
T
C
L
I
N
Site 14
S140
E
N
S
T
S
T
L
S
T
C
L
I
N
Q
I
Site 15
T248
D
L
S
T
I
R
I
T
P
T
D
S
R
W
V
Site 16
T250
S
T
I
R
I
T
P
T
D
S
R
W
V
G
A
Site 17
T282
P
F
F
F
L
P
Q
T
P
N
K
P
Q
K
E
Site 18
S293
P
Q
K
E
R
K
A
S
L
S
L
H
V
L
E
Site 19
S295
K
E
R
K
A
S
L
S
L
H
V
L
E
T
N
Site 20
T301
L
S
L
H
V
L
E
T
N
D
E
K
D
Q
T
Site 21
T308
T
N
D
E
K
D
Q
T
A
N
L
T
N
Q
G
Site 22
T319
T
N
Q
G
K
N
I
T
K
N
V
T
G
F
F
Site 23
T323
K
N
I
T
K
N
V
T
G
F
F
Q
S
F
K
Site 24
S328
N
V
T
G
F
F
Q
S
F
K
S
I
L
T
N
Site 25
Y362
A
F
T
Y
V
F
K
Y
V
E
Q
Q
Y
G
Q
Site 26
Y367
F
K
Y
V
E
Q
Q
Y
G
Q
P
S
S
K
A
Site 27
S372
Q
Q
Y
G
Q
P
S
S
K
A
N
I
L
L
G
Site 28
S450
D
G
N
N
P
V
T
S
H
R
D
V
P
L
S
Site 29
S491
P
C
L
A
G
C
K
S
S
S
G
N
K
K
P
Site 30
S493
L
A
G
C
K
S
S
S
G
N
K
K
P
I
V
Site 31
Y517
T
G
L
Q
N
R
N
Y
S
A
H
L
G
E
C
Site 32
S518
G
L
Q
N
R
N
Y
S
A
H
L
G
E
C
P
Site 33
T615
G
T
R
G
S
C
R
T
Y
N
S
T
S
F
S
Site 34
Y616
T
R
G
S
C
R
T
Y
N
S
T
S
F
S
R
Site 35
S618
G
S
C
R
T
Y
N
S
T
S
F
S
R
V
Y
Site 36
T619
S
C
R
T
Y
N
S
T
S
F
S
R
V
Y
L
Site 37
S620
C
R
T
Y
N
S
T
S
F
S
R
V
Y
L
G
Site 38
S622
T
Y
N
S
T
S
F
S
R
V
Y
L
G
L
S
Site 39
Y625
S
T
S
F
S
R
V
Y
L
G
L
S
S
M
L
Site 40
Y645
V
L
Y
I
I
L
I
Y
A
M
K
K
K
Y
Q
Site 41
Y651
I
Y
A
M
K
K
K
Y
Q
E
K
D
I
N
A
Site 42
S659
Q
E
K
D
I
N
A
S
E
N
G
S
V
M
D
Site 43
S663
I
N
A
S
E
N
G
S
V
M
D
E
A
N
L
Site 44
S672
M
D
E
A
N
L
E
S
L
N
K
N
K
H
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation