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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRSS21
Full Name:
Testisin
Alias:
Serine protease 21
Type:
Mass (Da):
34866
Number AA:
314
UniProt ID:
Q9Y6M0
International Prot ID:
IPI00305703
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000267
GO:0005624
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004175
GO:0004252
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0008152
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
A
G
L
R
K
P
E
S
Q
E
A
A
P
L
S
Site 2
S30
S
Q
E
A
A
P
L
S
G
P
C
G
R
R
V
Site 3
T39
P
C
G
R
R
V
I
T
S
R
I
V
G
G
E
Site 4
S40
C
G
R
R
V
I
T
S
R
I
V
G
G
E
D
Site 5
S70
D
S
H
V
C
G
V
S
L
L
S
H
R
W
A
Site 6
S88
A
H
C
F
E
T
Y
S
D
L
S
D
P
S
G
Site 7
S91
F
E
T
Y
S
D
L
S
D
P
S
G
W
M
V
Site 8
S108
G
Q
L
T
S
M
P
S
F
W
S
L
Q
A
Y
Site 9
Y115
S
F
W
S
L
Q
A
Y
Y
T
R
Y
F
V
S
Site 10
Y116
F
W
S
L
Q
A
Y
Y
T
R
Y
F
V
S
N
Site 11
Y119
L
Q
A
Y
Y
T
R
Y
F
V
S
N
I
Y
L
Site 12
S122
Y
Y
T
R
Y
F
V
S
N
I
Y
L
S
P
R
Site 13
Y125
R
Y
F
V
S
N
I
Y
L
S
P
R
Y
L
G
Site 14
S127
F
V
S
N
I
Y
L
S
P
R
Y
L
G
N
S
Site 15
Y130
N
I
Y
L
S
P
R
Y
L
G
N
S
P
Y
D
Site 16
S134
S
P
R
Y
L
G
N
S
P
Y
D
I
A
L
V
Site 17
Y136
R
Y
L
G
N
S
P
Y
D
I
A
L
V
K
L
Site 18
T148
V
K
L
S
A
P
V
T
Y
T
K
H
I
Q
P
Site 19
S161
Q
P
I
C
L
Q
A
S
T
F
E
F
E
N
R
Site 20
T162
P
I
C
L
Q
A
S
T
F
E
F
E
N
R
T
Site 21
S187
K
E
D
E
A
L
P
S
P
H
T
L
Q
E
V
Site 22
T190
E
A
L
P
S
P
H
T
L
Q
E
V
Q
V
A
Site 23
Y211
C
N
H
L
F
L
K
Y
S
F
R
K
D
I
F
Site 24
Y271
R
P
N
R
P
G
V
Y
T
N
I
S
H
H
F
Site 25
S291
L
M
A
Q
S
G
M
S
Q
P
D
P
S
W
P
Site 26
S296
G
M
S
Q
P
D
P
S
W
P
L
L
F
F
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation