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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CK1g3
Full Name:
Casein kinase I isoform gamma-3
Alias:
CK1-gamma3; CSNK1G3; EC 2.7.11.1; KC13; KC1G3
Type:
Protein-serine kinase, CK1 group, CK1 family
Mass (Da):
51389
Number AA:
447
UniProt ID:
Q9Y6M4
International Prot ID:
IPI00181294
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0016055
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
K
K
K
D
K
D
K
S
D
D
R
M
A
R
P
Site 2
S19
D
D
R
M
A
R
P
S
G
R
S
G
H
N
T
Site 3
S22
M
A
R
P
S
G
R
S
G
H
N
T
R
G
T
Site 4
T26
S
G
R
S
G
H
N
T
R
G
T
G
S
S
S
Site 5
T29
S
G
H
N
T
R
G
T
G
S
S
S
S
G
V
Site 6
S31
H
N
T
R
G
T
G
S
S
S
S
G
V
L
M
Site 7
S32
N
T
R
G
T
G
S
S
S
S
G
V
L
M
V
Site 8
S33
T
R
G
T
G
S
S
S
S
G
V
L
M
V
G
Site 9
S34
R
G
T
G
S
S
S
S
G
V
L
M
V
G
P
Site 10
Y64
L
R
L
G
K
N
L
Y
T
N
E
Y
V
A
I
Site 11
Y68
K
N
L
Y
T
N
E
Y
V
A
I
K
L
E
P
Site 12
S78
I
K
L
E
P
M
K
S
R
A
P
Q
L
H
L
Site 13
Y87
A
P
Q
L
H
L
E
Y
R
F
Y
K
Q
L
G
Site 14
Y90
L
H
L
E
Y
R
F
Y
K
Q
L
G
S
G
D
Site 15
S95
R
F
Y
K
Q
L
G
S
G
D
G
I
P
Q
V
Site 16
Y103
G
D
G
I
P
Q
V
Y
Y
F
G
P
C
G
K
Site 17
Y104
D
G
I
P
Q
V
Y
Y
F
G
P
C
G
K
Y
Site 18
Y152
Q
L
I
S
R
M
E
Y
V
H
S
K
N
L
I
Site 19
Y160
V
H
S
K
N
L
I
Y
R
D
V
K
P
E
N
Site 20
T177
I
G
R
P
G
N
K
T
Q
Q
V
I
H
I
I
Site 21
Y192
D
F
G
L
A
K
E
Y
I
D
P
E
T
K
K
Site 22
T197
K
E
Y
I
D
P
E
T
K
K
H
I
P
Y
R
Site 23
S208
I
P
Y
R
E
H
K
S
L
T
G
T
A
R
Y
Site 24
T212
E
H
K
S
L
T
G
T
A
R
Y
M
S
I
N
Site 25
Y215
S
L
T
G
T
A
R
Y
M
S
I
N
T
H
L
Site 26
S217
T
G
T
A
R
Y
M
S
I
N
T
H
L
G
K
Site 27
S227
T
H
L
G
K
E
Q
S
R
R
D
D
L
E
A
Site 28
T256
W
Q
G
L
K
A
D
T
L
K
E
R
Y
Q
K
Site 29
Y261
A
D
T
L
K
E
R
Y
Q
K
I
G
D
T
K
Site 30
T267
R
Y
Q
K
I
G
D
T
K
R
A
T
P
I
E
Site 31
T271
I
G
D
T
K
R
A
T
P
I
E
V
L
C
E
Site 32
Y286
N
F
P
E
M
A
T
Y
L
R
Y
V
R
R
L
Site 33
Y289
E
M
A
T
Y
L
R
Y
V
R
R
L
D
F
F
Site 34
Y301
D
F
F
E
K
P
D
Y
D
Y
L
R
K
L
F
Site 35
Y303
F
E
K
P
D
Y
D
Y
L
R
K
L
F
T
D
Site 36
Y317
D
L
F
D
R
K
G
Y
M
F
D
Y
E
Y
D
Site 37
Y321
R
K
G
Y
M
F
D
Y
E
Y
D
W
I
G
K
Site 38
Y323
G
Y
M
F
D
Y
E
Y
D
W
I
G
K
Q
L
Site 39
T332
W
I
G
K
Q
L
P
T
P
V
G
A
V
Q
Q
Site 40
S344
V
Q
Q
D
P
A
L
S
S
N
R
E
A
H
Q
Site 41
S345
Q
Q
D
P
A
L
S
S
N
R
E
A
H
Q
H
Site 42
S359
H
R
D
K
M
Q
Q
S
K
N
Q
S
A
D
H
Site 43
S392
A
A
D
R
H
G
G
S
V
Q
V
V
S
S
T
Site 44
S397
G
G
S
V
Q
V
V
S
S
T
N
G
E
L
N
Site 45
S398
G
S
V
Q
V
V
S
S
T
N
G
E
L
N
T
Site 46
T399
S
V
Q
V
V
S
S
T
N
G
E
L
N
T
D
Site 47
T405
S
T
N
G
E
L
N
T
D
D
P
T
A
G
R
Site 48
T409
E
L
N
T
D
D
P
T
A
G
R
S
N
A
P
Site 49
S413
D
D
P
T
A
G
R
S
N
A
P
I
T
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation