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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAMC3
Full Name:
Laminin subunit gamma-3
Alias:
Laminin-12 subunit gamma;Laminin-14 subunit gamma;Laminin-15 subunit gamma
Type:
Mass (Da):
172458
Number AA:
1587
UniProt ID:
Q9Y6N6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y26
G
A
G
M
G
A
C
Y
D
G
A
G
R
P
Q
Site 2
S51
F
G
R
L
A
Q
A
S
H
T
C
G
S
P
P
Site 3
S56
Q
A
S
H
T
C
G
S
P
P
E
D
F
C
P
Site 4
S89
P
Q
R
H
H
N
A
S
Y
L
T
D
F
H
S
Site 5
Y90
Q
R
H
H
N
A
S
Y
L
T
D
F
H
S
Q
Site 6
T121
Y
P
T
S
V
N
I
T
L
R
L
G
K
A
Y
Site 7
Y132
G
K
A
Y
E
I
T
Y
V
R
L
K
F
H
T
Site 8
T139
Y
V
R
L
K
F
H
T
S
R
P
E
S
F
A
Site 9
S140
V
R
L
K
F
H
T
S
R
P
E
S
F
A
I
Site 10
S144
F
H
T
S
R
P
E
S
F
A
I
Y
K
R
S
Site 11
Y148
R
P
E
S
F
A
I
Y
K
R
S
R
A
D
G
Site 12
S151
S
F
A
I
Y
K
R
S
R
A
D
G
P
W
E
Site 13
Y160
A
D
G
P
W
E
P
Y
Q
F
Y
S
A
S
C
Site 14
T170
Y
S
A
S
C
Q
K
T
Y
G
R
P
E
G
Q
Site 15
Y171
S
A
S
C
Q
K
T
Y
G
R
P
E
G
Q
Y
Site 16
Y178
Y
G
R
P
E
G
Q
Y
L
R
P
G
E
D
E
Site 17
T191
D
E
R
V
A
F
C
T
S
E
F
S
D
I
S
Site 18
S192
E
R
V
A
F
C
T
S
E
F
S
D
I
S
P
Site 19
S198
T
S
E
F
S
D
I
S
P
L
S
G
G
N
V
Site 20
S208
S
G
G
N
V
A
F
S
T
L
E
G
R
P
S
Site 21
T209
G
G
N
V
A
F
S
T
L
E
G
R
P
S
A
Site 22
S215
S
T
L
E
G
R
P
S
A
Y
N
F
E
E
S
Site 23
S222
S
A
Y
N
F
E
E
S
P
G
L
Q
E
W
V
Site 24
T243
I
S
L
D
R
L
N
T
F
G
D
D
I
F
K
Site 25
S257
K
D
P
K
V
L
Q
S
Y
Y
Y
A
V
S
D
Site 26
Y258
D
P
K
V
L
Q
S
Y
Y
Y
A
V
S
D
F
Site 27
Y259
P
K
V
L
Q
S
Y
Y
Y
A
V
S
D
F
S
Site 28
S263
Q
S
Y
Y
Y
A
V
S
D
F
S
V
G
G
R
Site 29
T317
D
R
P
W
A
R
G
T
A
E
A
A
H
E
C
Site 30
T337
S
G
R
S
E
E
C
T
F
D
R
E
L
F
R
Site 31
S345
F
D
R
E
L
F
R
S
T
G
H
G
G
R
C
Site 32
T346
D
R
E
L
F
R
S
T
G
H
G
G
R
C
H
Site 33
T398
L
H
L
Q
C
D
D
T
G
T
C
A
C
K
P
Site 34
S421
R
C
L
P
G
F
H
S
L
S
E
G
G
C
R
Site 35
S423
L
P
G
F
H
S
L
S
E
G
G
C
R
P
C
Site 36
T431
E
G
G
C
R
P
C
T
C
N
P
A
G
S
L
Site 37
T440
N
P
A
G
S
L
D
T
C
D
P
R
S
G
R
Site 38
S445
L
D
T
C
D
P
R
S
G
R
C
P
C
K
E
Site 39
S515
A
E
G
W
W
A
R
S
V
G
G
S
E
H
P
Site 40
S519
W
A
R
S
V
G
G
S
E
H
P
P
Q
W
S
Site 41
S526
S
E
H
P
P
Q
W
S
P
N
G
V
L
L
S
Site 42
S533
S
P
N
G
V
L
L
S
P
E
D
E
E
E
L
Site 43
T541
P
E
D
E
E
E
L
T
A
P
E
K
F
L
G
Site 44
Y554
L
G
D
Q
R
F
S
Y
G
Q
P
L
I
L
T
Site 45
T561
Y
G
Q
P
L
I
L
T
F
R
V
P
P
G
D
Site 46
S569
F
R
V
P
P
G
D
S
P
L
P
V
Q
L
R
Site 47
S585
E
G
T
G
L
A
L
S
L
R
H
S
S
L
S
Site 48
S589
L
A
L
S
L
R
H
S
S
L
S
G
P
Q
D
Site 49
S590
A
L
S
L
R
H
S
S
L
S
G
P
Q
D
A
Site 50
S592
S
L
R
H
S
S
L
S
G
P
Q
D
A
G
H
Site 51
S613
R
F
H
L
Q
E
T
S
E
D
V
A
P
P
L
Site 52
S640
T
S
L
R
L
R
V
S
P
G
P
S
P
A
G
Site 53
S658
L
T
E
V
R
L
T
S
A
R
P
G
L
S
P
Site 54
S664
T
S
A
R
P
G
L
S
P
P
A
S
W
V
E
Site 55
Y691
C
E
S
C
A
P
G
Y
K
R
E
M
P
Q
G
Site 56
Y701
E
M
P
Q
G
G
P
Y
A
S
C
V
P
C
T
Site 57
T728
I
C
V
C
S
H
H
T
E
G
P
S
C
E
R
Site 58
S732
S
H
H
T
E
G
P
S
C
E
R
C
L
P
G
Site 59
Y741
E
R
C
L
P
G
F
Y
G
N
P
F
A
G
Q
Site 60
T765
P
G
Q
S
A
C
T
T
I
P
E
S
R
E
V
Site 61
T775
E
S
R
E
V
V
C
T
H
C
P
P
G
Q
R
Site 62
Y902
A
R
D
C
S
R
C
Y
P
G
F
F
D
L
Q
Site 63
T937
H
P
K
T
G
Q
C
T
C
R
P
G
V
T
G
Site 64
Y992
C
R
P
G
F
E
G
Y
K
C
D
R
C
H
D
Site 65
T1032
A
K
L
K
A
R
L
T
L
T
E
G
W
L
Q
Site 66
T1034
L
K
A
R
L
T
L
T
E
G
W
L
Q
G
S
Site 67
S1041
T
E
G
W
L
Q
G
S
D
C
G
S
P
W
G
Site 68
S1045
L
Q
G
S
D
C
G
S
P
W
G
P
L
D
I
Site 69
Y1063
E
A
P
R
G
D
V
Y
Q
G
H
H
L
L
P
Site 70
S1108
A
R
C
A
Q
A
G
S
Q
K
T
C
T
Q
L
Site 71
S1125
L
E
A
V
L
E
S
S
E
E
E
I
L
H
A
Site 72
S1147
E
I
P
Q
E
G
P
S
Q
P
T
K
W
S
H
Site 73
T1157
T
K
W
S
H
L
A
T
E
A
R
A
L
A
R
Site 74
S1165
E
A
R
A
L
A
R
S
H
R
D
T
A
T
K
Site 75
T1169
L
A
R
S
H
R
D
T
A
T
K
I
A
A
T
Site 76
T1171
R
S
H
R
D
T
A
T
K
I
A
A
T
A
W
Site 77
T1203
E
G
R
V
A
L
E
T
Q
R
D
L
E
D
R
Site 78
Y1211
Q
R
D
L
E
D
R
Y
Q
E
V
Q
A
A
Q
Site 79
S1263
P
G
A
L
P
Q
K
S
R
A
E
D
L
G
L
Site 80
T1278
K
A
K
A
L
E
K
T
V
A
S
W
Q
H
M
Site 81
T1304
A
Q
A
T
L
R
Q
T
E
P
L
T
K
A
R
Site 82
T1308
L
R
Q
T
E
P
L
T
K
A
R
S
R
L
T
Site 83
S1312
E
P
L
T
K
A
R
S
R
L
T
A
T
S
A
Site 84
T1315
T
K
A
R
S
R
L
T
A
T
S
A
S
Q
L
Site 85
T1317
A
R
S
R
L
T
A
T
S
A
S
Q
L
H
Q
Site 86
S1318
R
S
R
L
T
A
T
S
A
S
Q
L
H
Q
E
Site 87
T1331
Q
E
A
R
A
A
L
T
Q
A
S
S
S
V
Q
Site 88
S1376
A
L
Q
R
K
A
D
S
V
S
D
R
L
L
A
Site 89
S1378
Q
R
K
A
D
S
V
S
D
R
L
L
A
D
T
Site 90
T1385
S
D
R
L
L
A
D
T
R
K
K
T
K
Q
A
Site 91
T1389
L
A
D
T
R
K
K
T
K
Q
A
E
R
M
L
Site 92
S1403
L
G
N
A
A
P
L
S
S
S
A
K
K
K
G
Site 93
S1405
N
A
A
P
L
S
S
S
A
K
K
K
G
R
E
Site 94
S1439
K
Q
A
H
R
R
A
S
R
L
T
S
Q
T
Q
Site 95
T1442
H
R
R
A
S
R
L
T
S
Q
T
Q
A
T
L
Site 96
S1443
R
R
A
S
R
L
T
S
Q
T
Q
A
T
L
Q
Site 97
T1445
A
S
R
L
T
S
Q
T
Q
A
T
L
Q
Q
A
Site 98
S1459
A
S
Q
Q
V
L
A
S
E
A
R
R
Q
E
L
Site 99
S1477
E
R
V
G
A
G
L
S
E
M
E
Q
Q
I
R
Site 100
S1486
M
E
Q
Q
I
R
E
S
R
I
S
L
E
K
D
Site 101
S1489
Q
I
R
E
S
R
I
S
L
E
K
D
I
E
T
Site 102
T1496
S
L
E
K
D
I
E
T
L
S
E
L
L
A
R
Site 103
S1506
E
L
L
A
R
L
G
S
L
D
T
H
Q
A
P
Site 104
S1533
R
L
R
L
Q
L
G
S
P
G
S
L
Q
R
K
Site 105
S1536
L
Q
L
G
S
P
G
S
L
Q
R
K
L
S
L
Site 106
S1542
G
S
L
Q
R
K
L
S
L
L
E
Q
E
S
Q
Site 107
S1548
L
S
L
L
E
Q
E
S
Q
Q
Q
E
L
Q
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation