KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
USH1C
Full Name:
Harmonin
Alias:
Antigen NY-CO-38/NY-CO-37;Autoimmune enteropathy-related antigen AIE-75;Protein PDZ-73;Renal carcinoma antigen NY-REN-3;Usher syndrome type-1C protein
Type:
Mass (Da):
62211
Number AA:
552
UniProt ID:
Q9Y6N9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y25
E
N
D
A
E
K
D
Y
L
Y
D
V
L
R
M
Site 2
Y27
D
A
E
K
D
Y
L
Y
D
V
L
R
M
Y
H
Site 3
Y33
L
Y
D
V
L
R
M
Y
H
Q
T
M
D
V
A
Site 4
Y74
P
L
K
H
Q
V
E
Y
D
Q
L
T
P
R
R
Site 5
T78
Q
V
E
Y
D
Q
L
T
P
R
R
S
R
K
L
Site 6
S82
D
Q
L
T
P
R
R
S
R
K
L
K
E
V
R
Site 7
S101
H
P
E
G
L
G
L
S
V
R
G
G
L
E
F
Site 8
S125
I
K
G
G
Q
A
D
S
V
G
L
Q
V
G
D
Site 9
Y140
E
I
V
R
I
N
G
Y
S
I
S
S
C
T
H
Site 10
S141
I
V
R
I
N
G
Y
S
I
S
S
C
T
H
E
Site 11
S143
R
I
N
G
Y
S
I
S
S
C
T
H
E
E
V
Site 12
T159
N
L
I
R
T
K
K
T
V
S
I
K
V
R
H
Site 13
S161
I
R
T
K
K
T
V
S
I
K
V
R
H
I
G
Site 14
S175
G
L
I
P
V
K
S
S
P
D
E
P
L
T
W
Site 15
T181
S
S
P
D
E
P
L
T
W
Q
Y
V
D
Q
F
Site 16
Y184
D
E
P
L
T
W
Q
Y
V
D
Q
F
V
S
E
Site 17
S190
Q
Y
V
D
Q
F
V
S
E
S
G
G
V
R
G
Site 18
S192
V
D
Q
F
V
S
E
S
G
G
V
R
G
S
L
Site 19
S198
E
S
G
G
V
R
G
S
L
G
S
P
G
N
R
Site 20
S201
G
V
R
G
S
L
G
S
P
G
N
R
E
N
K
Site 21
S215
K
E
K
K
V
F
I
S
L
V
G
S
R
G
L
Site 22
S225
G
S
R
G
L
G
C
S
I
S
S
G
P
I
Q
Site 23
S227
R
G
L
G
C
S
I
S
S
G
P
I
Q
K
P
Site 24
S239
Q
K
P
G
I
F
I
S
H
V
K
P
G
S
L
Site 25
S267
E
V
N
G
V
D
F
S
N
L
D
H
K
E
A
Site 26
S280
E
A
V
N
V
L
K
S
S
R
S
L
T
I
S
Site 27
T299
A
G
R
E
L
F
M
T
D
R
E
R
L
A
E
Site 28
S327
Q
K
R
L
A
M
E
S
N
K
I
L
Q
E
Q
Site 29
Y356
A
A
E
E
N
E
R
Y
R
K
E
M
E
Q
I
Site 30
S380
Q
W
E
E
D
W
G
S
K
E
Q
L
L
L
P
Site 31
T389
E
Q
L
L
L
P
K
T
I
T
A
E
V
H
P
Site 32
Y404
V
P
L
R
K
P
K
Y
D
Q
G
V
E
P
E
Site 33
T422
A
D
D
L
D
G
G
T
E
E
Q
G
E
Q
D
Site 34
Y433
G
E
Q
D
F
R
K
Y
E
E
G
F
D
P
Y
Site 35
Y440
Y
E
E
G
F
D
P
Y
S
M
F
T
P
E
Q
Site 36
S441
E
E
G
F
D
P
Y
S
M
F
T
P
E
Q
I
Site 37
T444
F
D
P
Y
S
M
F
T
P
E
Q
I
M
G
K
Site 38
S463
L
R
I
K
K
E
G
S
L
D
L
A
L
E
G
Site 39
Y485
K
V
V
V
S
A
V
Y
E
R
G
A
A
E
R
Site 40
Y513
N
G
K
I
V
T
D
Y
T
L
A
E
A
E
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation