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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CAPN6
Full Name:
Calpain-6
Alias:
Calpain-like protease X-linked;Calpamodulin
Type:
Mass (Da):
74576
Number AA:
641
UniProt ID:
Q9Y6Q1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
K
L
F
K
N
Q
K
Y
Q
E
L
K
Q
E
C
Site 2
T31
S
R
L
F
C
D
P
T
F
L
P
E
N
D
S
Site 3
S38
T
F
L
P
E
N
D
S
L
F
Y
N
R
L
L
Site 4
Y41
P
E
N
D
S
L
F
Y
N
R
L
L
P
G
K
Site 5
T74
N
I
S
N
H
Q
L
T
Q
G
R
L
G
H
K
Site 6
T98
A
V
Q
E
S
H
W
T
K
T
I
P
N
H
K
Site 7
Y117
D
P
Q
K
T
E
K
Y
A
G
I
F
H
F
R
Site 8
S150
I
N
G
D
L
V
F
S
F
S
T
S
M
N
E
Site 9
T196
F
T
G
T
L
A
E
T
V
D
M
Q
K
G
R
Site 10
T205
D
M
Q
K
G
R
Y
T
E
L
V
E
E
K
Y
Site 11
Y212
T
E
L
V
E
E
K
Y
K
L
F
G
E
L
Y
Site 12
Y219
Y
K
L
F
G
E
L
Y
K
T
F
T
K
G
G
Site 13
S234
L
I
C
C
S
I
E
S
P
N
Q
E
E
Q
E
Site 14
Y254
G
L
L
K
G
H
T
Y
T
M
T
D
I
R
K
Site 15
T257
K
G
H
T
Y
T
M
T
D
I
R
K
I
R
L
Site 16
Y278
V
F
S
A
E
K
V
Y
M
V
R
L
R
N
P
Site 17
S292
P
L
G
R
Q
E
W
S
G
P
W
S
E
I
S
Site 18
S299
S
G
P
W
S
E
I
S
E
E
W
Q
Q
L
T
Site 19
T306
S
E
E
W
Q
Q
L
T
A
S
D
R
K
N
L
Site 20
S308
E
W
Q
Q
L
T
A
S
D
R
K
N
L
G
L
Site 21
Y375
M
N
R
S
G
G
C
Y
N
N
R
D
T
F
L
Site 22
Y387
T
F
L
Q
N
P
Q
Y
I
F
T
V
P
E
D
Site 23
T390
Q
N
P
Q
Y
I
F
T
V
P
E
D
G
H
K
Site 24
S401
D
G
H
K
V
I
M
S
L
Q
Q
K
D
L
R
Site 25
T409
L
Q
Q
K
D
L
R
T
Y
R
R
M
G
R
P
Site 26
Y410
Q
Q
K
D
L
R
T
Y
R
R
M
G
R
P
D
Site 27
Y419
R
M
G
R
P
D
N
Y
I
I
G
F
E
L
F
Site 28
Y440
K
F
R
L
H
H
L
Y
I
Q
E
R
A
G
T
Site 29
T447
Y
I
Q
E
R
A
G
T
S
T
Y
I
D
T
R
Site 30
T449
Q
E
R
A
G
T
S
T
Y
I
D
T
R
T
V
Site 31
Y450
E
R
A
G
T
S
T
Y
I
D
T
R
T
V
F
Site 32
T453
G
T
S
T
Y
I
D
T
R
T
V
F
L
S
K
Site 33
T455
S
T
Y
I
D
T
R
T
V
F
L
S
K
Y
L
Site 34
S459
D
T
R
T
V
F
L
S
K
Y
L
K
K
G
N
Site 35
Y461
R
T
V
F
L
S
K
Y
L
K
K
G
N
Y
V
Site 36
Y467
K
Y
L
K
K
G
N
Y
V
L
V
P
T
M
F
Site 37
T498
P
V
Q
L
R
E
L
T
L
D
M
P
K
M
S
Site 38
T518
R
G
Y
P
K
V
V
T
Q
I
T
V
H
S
A
Site 39
T536
E
K
K
Y
A
N
E
T
V
N
P
Y
L
V
I
Site 40
Y540
A
N
E
T
V
N
P
Y
L
V
I
K
C
G
K
Site 41
S552
C
G
K
E
E
V
R
S
P
V
Q
K
N
T
V
Site 42
T558
R
S
P
V
Q
K
N
T
V
H
A
I
F
D
T
Site 43
T565
T
V
H
A
I
F
D
T
Q
A
I
F
Y
R
R
Site 44
S603
V
T
L
D
A
D
P
S
D
C
R
D
L
K
S
Site 45
S610
S
D
C
R
D
L
K
S
L
Y
L
R
K
K
G
Site 46
Y612
C
R
D
L
K
S
L
Y
L
R
K
K
G
G
P
Site 47
S629
K
V
K
Q
G
H
I
S
F
K
V
I
S
S
D
Site 48
S634
H
I
S
F
K
V
I
S
S
D
D
L
T
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation