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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TNFRSF11A
Full Name:
Tumor necrosis factor receptor superfamily member 11A
Alias:
CD265; ODFR; OFE; osteoclast differentiation factor receptor; RANK; receptor activator of NF-KB; TNR11; TRANCER; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Type:
Mass (Da):
66030
Number AA:
UniProt ID:
Q9Y6Q6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0007267
GO:0008284
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S258
N
E
A
C
G
R
L
S
G
D
K
E
S
S
G
Site 2
S263
R
L
S
G
D
K
E
S
S
G
D
S
C
V
S
Site 3
S264
L
S
G
D
K
E
S
S
G
D
S
C
V
S
T
Site 4
S267
D
K
E
S
S
G
D
S
C
V
S
T
H
T
A
Site 5
S270
S
S
G
D
S
C
V
S
T
H
T
A
N
F
G
Site 6
T271
S
G
D
S
C
V
S
T
H
T
A
N
F
G
Q
Site 7
T294
L
L
T
L
E
E
K
T
F
P
E
D
M
C
Y
Site 8
T311
Q
G
G
V
C
Q
G
T
C
V
G
G
G
P
Y
Site 9
S328
G
E
D
A
R
M
L
S
L
V
S
K
T
E
I
Site 10
S339
K
T
E
I
E
E
D
S
F
R
Q
M
P
T
E
Site 11
Y349
Q
M
P
T
E
D
E
Y
M
D
R
P
S
Q
P
Site 12
S354
D
E
Y
M
D
R
P
S
Q
P
T
D
Q
L
L
Site 13
T364
T
D
Q
L
L
F
L
T
E
P
G
S
K
S
T
Site 14
S368
L
F
L
T
E
P
G
S
K
S
T
P
P
F
S
Site 15
S370
L
T
E
P
G
S
K
S
T
P
P
F
S
E
P
Site 16
T371
T
E
P
G
S
K
S
T
P
P
F
S
E
P
L
Site 17
S375
S
K
S
T
P
P
F
S
E
P
L
E
V
G
E
Site 18
S385
L
E
V
G
E
N
D
S
L
S
Q
C
F
T
G
Site 19
S387
V
G
E
N
D
S
L
S
Q
C
F
T
G
T
Q
Site 20
T391
D
S
L
S
Q
C
F
T
G
T
Q
S
T
V
G
Site 21
T393
L
S
Q
C
F
T
G
T
Q
S
T
V
G
S
E
Site 22
S395
Q
C
F
T
G
T
Q
S
T
V
G
S
E
S
C
Site 23
T396
C
F
T
G
T
Q
S
T
V
G
S
E
S
C
N
Site 24
S399
G
T
Q
S
T
V
G
S
E
S
C
N
C
T
E
Site 25
T405
G
S
E
S
C
N
C
T
E
P
L
C
R
T
D
Site 26
T414
P
L
C
R
T
D
W
T
P
M
S
S
E
N
Y
Site 27
S417
R
T
D
W
T
P
M
S
S
E
N
Y
L
Q
K
Site 28
Y421
T
P
M
S
S
E
N
Y
L
Q
K
E
V
D
S
Site 29
S463
D
C
E
P
L
V
G
S
P
K
R
G
P
L
P
Site 30
Y474
G
P
L
P
Q
C
A
Y
G
M
G
L
P
P
E
Site 31
S485
L
P
P
E
E
E
A
S
R
T
E
A
R
D
Q
Site 32
T487
P
E
E
E
A
S
R
T
E
A
R
D
Q
P
E
Site 33
S503
G
A
D
G
R
L
P
S
S
A
R
A
G
A
G
Site 34
S504
A
D
G
R
L
P
S
S
A
R
A
G
A
G
S
Site 35
S511
S
A
R
A
G
A
G
S
G
S
S
P
G
G
Q
Site 36
S513
R
A
G
A
G
S
G
S
S
P
G
G
Q
S
P
Site 37
S514
A
G
A
G
S
G
S
S
P
G
G
Q
S
P
A
Site 38
S519
G
S
S
P
G
G
Q
S
P
A
S
G
N
V
T
Site 39
S522
P
G
G
Q
S
P
A
S
G
N
V
T
G
N
S
Site 40
T526
S
P
A
S
G
N
V
T
G
N
S
N
S
T
F
Site 41
S529
S
G
N
V
T
G
N
S
N
S
T
F
I
S
S
Site 42
S531
N
V
T
G
N
S
N
S
T
F
I
S
S
G
Q
Site 43
T532
V
T
G
N
S
N
S
T
F
I
S
S
G
Q
V
Site 44
S535
N
S
N
S
T
F
I
S
S
G
Q
V
M
N
F
Site 45
Y550
K
G
D
I
I
V
V
Y
V
S
Q
T
S
Q
E
Site 46
T574
G
R
P
V
Q
E
E
T
L
A
R
R
D
S
F
Site 47
S580
E
T
L
A
R
R
D
S
F
A
G
N
G
P
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation