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Updated November 2019
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Protein Info
Short Name:
FCGBP
Full Name:
IgGFc-binding protein
Alias:
Fcgamma-binding protein antigen
Type:
Mass (Da):
572017
Number AA:
5405
UniProt ID:
Q9Y6R7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
W
G
L
T
Q
E
A
S
V
D
L
K
N
T
G
Site 2
T38
T
G
R
E
E
F
L
T
A
F
L
Q
N
Y
Q
Site 3
Y44
L
T
A
F
L
Q
N
Y
Q
L
A
Y
S
K
A
Site 4
Y52
Q
L
A
Y
S
K
A
Y
P
R
L
L
I
S
S
Site 5
S59
Y
P
R
L
L
I
S
S
L
S
E
S
P
A
S
Site 6
S71
P
A
S
V
S
I
L
S
Q
A
D
N
T
S
K
Site 7
T81
D
N
T
S
K
K
V
T
V
R
P
G
E
S
V
Site 8
S117
I
H
S
D
Y
A
I
S
V
Q
A
L
N
A
K
Site 9
T127
A
L
N
A
K
P
D
T
A
E
L
T
L
L
R
Site 10
T131
K
P
D
T
A
E
L
T
L
L
R
P
I
Q
A
Site 11
T147
G
T
E
Y
F
V
L
T
P
P
G
T
S
A
R
Site 12
T179
V
T
L
K
G
S
V
T
F
N
G
K
F
Y
P
Site 13
Y185
V
T
F
N
G
K
F
Y
P
A
G
D
V
L
R
Site 14
Y198
L
R
V
T
L
Q
P
Y
N
V
A
Q
L
Q
S
Site 15
S205
Y
N
V
A
Q
L
Q
S
S
V
D
L
S
G
S
Site 16
S206
N
V
A
Q
L
Q
S
S
V
D
L
S
G
S
K
Site 17
S210
L
Q
S
S
V
D
L
S
G
S
K
V
T
A
S
Site 18
S212
S
S
V
D
L
S
G
S
K
V
T
A
S
S
P
Site 19
S224
S
S
P
V
A
V
L
S
G
H
S
C
A
Q
K
Site 20
T256
G
T
H
Y
V
V
P
T
L
A
S
Q
S
R
Y
Site 21
S259
Y
V
V
P
T
L
A
S
Q
S
R
Y
D
L
A
Site 22
T277
A
S
Q
A
T
K
L
T
Y
N
H
G
G
I
T
Site 23
Y278
S
Q
A
T
K
L
T
Y
N
H
G
G
I
T
G
Site 24
S302
V
E
F
E
V
R
P
S
W
P
L
Y
L
S
A
Site 25
S389
T
W
E
A
V
P
G
S
E
F
S
Y
A
E
V
Site 26
Y393
V
P
G
S
E
F
S
Y
A
E
V
E
L
G
T
Site 27
S438
D
C
G
R
T
V
L
S
P
V
E
P
S
C
E
Site 28
Y480
R
A
Q
G
D
P
H
Y
T
T
F
D
G
R
R
Site 29
T482
Q
G
D
P
H
Y
T
T
F
D
G
R
R
Y
D
Site 30
Y488
T
T
F
D
G
R
R
Y
D
M
M
G
T
C
S
Site 31
T507
E
L
C
S
E
D
D
T
L
P
A
F
S
V
E
Site 32
S522
A
K
N
E
H
R
G
S
R
R
V
S
Y
V
G
Site 33
S526
H
R
G
S
R
R
V
S
Y
V
G
L
V
T
V
Site 34
Y527
R
G
S
R
R
V
S
Y
V
G
L
V
T
V
R
Site 35
S539
T
V
R
A
Y
S
H
S
V
S
L
T
R
G
E
Site 36
S541
R
A
Y
S
H
S
V
S
L
T
R
G
E
V
G
Site 37
T543
Y
S
H
S
V
S
L
T
R
G
E
V
G
F
V
Site 38
S562
Q
R
S
R
L
P
V
S
L
S
E
G
R
L
R
Site 39
S564
S
R
L
P
V
S
L
S
E
G
R
L
R
V
Y
Site 40
Y571
S
E
G
R
L
R
V
Y
Q
S
G
P
R
A
V
Site 41
S573
G
R
L
R
V
Y
Q
S
G
P
R
A
V
V
E
Site 42
S598
W
D
C
Q
L
A
L
S
L
P
A
R
F
Q
D
Site 43
T624
D
P
A
D
D
F
L
T
P
D
G
A
L
A
P
Site 44
S639
D
A
V
E
F
A
S
S
W
K
L
D
D
G
D
Site 45
Y647
W
K
L
D
D
G
D
Y
L
C
E
D
G
C
Q
Site 46
Y668
T
P
G
Q
A
Q
H
Y
E
G
D
R
L
C
G
Site 47
S737
I
S
V
G
D
W
R
S
P
A
N
C
P
L
S
Site 48
S744
S
P
A
N
C
P
L
S
C
P
A
N
S
R
Y
Site 49
Y751
S
C
P
A
N
S
R
Y
E
L
C
G
P
A
C
Site 50
S769
C
N
G
A
A
A
P
S
N
C
S
G
R
P
C
Site 51
S772
A
A
A
P
S
N
C
S
G
R
P
C
V
E
G
Site 52
T834
N
G
A
T
H
Q
V
T
C
R
D
K
Q
S
C
Site 53
S848
C
P
A
G
E
R
C
S
V
Q
N
G
L
L
G
Site 54
Y857
Q
N
G
L
L
G
C
Y
P
D
R
F
G
T
C
Site 55
T863
C
Y
P
D
R
F
G
T
C
Q
G
S
G
D
P
Site 56
S867
R
F
G
T
C
Q
G
S
G
D
P
H
Y
V
S
Site 57
Y872
Q
G
S
G
D
P
H
Y
V
S
F
D
G
R
R
Site 58
S874
S
G
D
P
H
Y
V
S
F
D
G
R
R
F
D
Site 59
S914
V
E
N
E
H
R
G
S
Q
T
V
S
Y
T
R
Site 60
T916
N
E
H
R
G
S
Q
T
V
S
Y
T
R
A
V
Site 61
S918
H
R
G
S
Q
T
V
S
Y
T
R
A
V
R
V
Site 62
Y919
R
G
S
Q
T
V
S
Y
T
R
A
V
R
V
E
Site 63
Y938
K
V
A
V
R
R
E
Y
P
G
Q
V
L
V
D
Site 64
T978
V
R
T
D
F
G
L
T
V
T
Y
D
W
N
A
Site 65
T988
Y
D
W
N
A
R
V
T
A
K
V
P
S
S
Y
Site 66
S1031
N
A
L
A
F
G
N
S
W
Q
E
E
T
R
P
Site 67
S1053
G
D
C
P
K
L
D
S
L
V
A
Q
Q
L
Q
Site 68
T1122
A
C
Q
A
A
G
A
T
V
H
P
W
R
S
E
Site 69
S1128
A
T
V
H
P
W
R
S
E
E
L
C
P
L
S
Site 70
S1135
S
E
E
L
C
P
L
S
C
P
P
H
S
H
Y
Site 71
Y1147
S
H
Y
E
A
C
S
Y
G
C
P
L
S
C
G
Site 72
Y1197
G
C
V
H
Q
G
T
Y
H
P
P
G
Q
T
F
Site 73
T1203
T
Y
H
P
P
G
Q
T
F
Y
P
G
P
G
C
Site 74
Y1205
H
P
P
G
Q
T
F
Y
P
G
P
G
C
D
S
Site 75
S1223
C
Q
E
G
G
L
V
S
C
E
S
S
S
C
G
Site 76
S1226
G
G
L
V
S
C
E
S
S
S
C
G
P
H
E
Site 77
S1227
G
L
V
S
C
E
S
S
S
C
G
P
H
E
A
Site 78
S1228
L
V
S
C
E
S
S
S
C
G
P
H
E
A
C
Site 79
S1238
P
H
E
A
C
Q
P
S
G
G
S
L
G
C
V
Site 80
S1255
G
S
S
T
C
Q
A
S
G
D
P
H
Y
T
T
Site 81
Y1260
Q
A
S
G
D
P
H
Y
T
T
F
D
G
R
R
Site 82
T1262
S
G
D
P
H
Y
T
T
F
D
G
R
R
F
D
Site 83
T1330
E
Q
R
Q
W
K
V
T
V
N
G
V
D
M
K
Site 84
S1350
A
N
G
Q
I
R
A
S
Q
H
G
S
D
V
V
Site 85
S1354
I
R
A
S
Q
H
G
S
D
V
V
I
E
T
D
Site 86
Y1382
R
V
T
V
P
G
N
Y
Y
Q
Q
M
C
G
L
Site 87
S1407
D
F
Q
K
P
N
G
S
Q
A
G
N
A
N
E
Site 88
S1418
N
A
N
E
F
G
N
S
W
E
E
V
V
P
D
Site 89
S1426
W
E
E
V
V
P
D
S
P
C
L
P
P
T
P
Site 90
T1432
D
S
P
C
L
P
P
T
P
C
P
P
G
S
E
Site 91
S1438
P
T
P
C
P
P
G
S
E
D
C
I
P
S
H
Site 92
S1444
G
S
E
D
C
I
P
S
H
K
C
P
P
E
L
Site 93
Y1455
P
P
E
L
E
K
K
Y
Q
K
E
E
F
C
G
Site 94
S1465
E
E
F
C
G
L
L
S
S
P
T
G
P
L
S
Site 95
S1472
S
S
P
T
G
P
L
S
S
C
H
K
L
V
D
Site 96
S1473
S
P
T
G
P
L
S
S
C
H
K
L
V
D
P
Site 97
Y1538
E
C
P
P
N
S
H
Y
E
L
C
A
D
T
C
Site 98
S1550
D
T
C
S
L
G
C
S
A
L
S
A
P
P
Q
Site 99
S1553
S
L
G
C
S
A
L
S
A
P
P
Q
C
Q
D
Site 100
Y1574
Q
C
D
S
G
F
L
Y
N
G
Q
A
C
V
P
Site 101
Y1593
G
C
Y
H
N
G
V
Y
Y
E
P
E
Q
T
V
Site 102
Y1594
C
Y
H
N
G
V
Y
Y
E
P
E
Q
T
V
L
Site 103
S1638
Q
P
S
G
G
I
L
S
C
V
T
K
D
P
C
Site 104
T1649
K
D
P
C
H
G
V
T
C
R
P
Q
E
T
C
Site 105
Y1681
W
L
W
G
D
P
H
Y
H
S
F
D
G
R
K
Site 106
T1713
G
V
S
T
Q
G
L
T
P
F
T
V
T
T
K
Site 107
T1716
T
Q
G
L
T
P
F
T
V
T
T
K
N
Q
N
Site 108
S1745
A
A
L
G
T
N
I
S
I
H
K
D
E
I
G
Site 109
S1773
S
V
A
D
G
R
I
S
V
T
Q
G
A
S
K
Site 110
T1775
A
D
G
R
I
S
V
T
Q
G
A
S
K
A
L
Site 111
T1802
W
N
W
R
V
D
V
T
L
P
S
S
Y
H
G
Site 112
S1836
P
N
G
T
L
A
P
S
I
P
I
W
G
G
S
Site 113
T1863
E
C
R
G
S
C
P
T
C
P
E
D
R
L
E
Site 114
Y1872
P
E
D
R
L
E
Q
Y
E
G
P
G
F
C
G
Site 115
T1890
P
G
T
G
G
P
F
T
T
C
H
A
H
V
P
Site 116
Y1956
T
C
P
E
N
S
H
Y
E
V
C
G
S
P
C
Site 117
S1961
S
H
Y
E
V
C
G
S
P
C
P
A
S
C
P
Site 118
S1969
P
C
P
A
S
C
P
S
P
A
P
L
T
T
P
Site 119
T1975
P
S
P
A
P
L
T
T
P
A
V
C
E
G
P
Site 120
Y2015
G
C
W
A
N
G
T
Y
H
E
A
G
S
E
F
Site 121
S2059
E
V
C
G
L
L
P
S
G
Q
H
G
C
Q
P
Site 122
Y2080
Q
A
W
G
D
P
H
Y
V
T
L
D
G
H
R
Site 123
Y2096
N
F
Q
G
T
C
E
Y
L
L
S
A
P
C
H
Site 124
S2099
G
T
C
E
Y
L
L
S
A
P
C
H
G
P
P
Site 125
T2113
P
L
G
A
E
N
F
T
V
T
V
A
N
E
H
Site 126
T2115
G
A
E
N
F
T
V
T
V
A
N
E
H
R
G
Site 127
S2123
V
A
N
E
H
R
G
S
Q
A
V
S
Y
T
R
Site 128
S2127
H
R
G
S
Q
A
V
S
Y
T
R
S
V
T
L
Site 129
Y2128
R
G
S
Q
A
V
S
Y
T
R
S
V
T
L
Q
Site 130
T2129
G
S
Q
A
V
S
Y
T
R
S
V
T
L
Q
I
Site 131
S2131
Q
A
V
S
Y
T
R
S
V
T
L
Q
I
Y
N
Site 132
T2133
V
S
Y
T
R
S
V
T
L
Q
I
Y
N
H
S
Site 133
Y2137
R
S
V
T
L
Q
I
Y
N
H
S
L
T
L
S
Site 134
S2140
T
L
Q
I
Y
N
H
S
L
T
L
S
A
R
W
Site 135
T2142
Q
I
Y
N
H
S
L
T
L
S
A
R
W
P
R
Site 136
S2144
Y
N
H
S
L
T
L
S
A
R
W
P
R
K
L
Site 137
S2250
C
V
S
K
P
C
P
S
P
C
T
P
E
Q
Q
Site 138
T2253
K
P
C
P
S
P
C
T
P
E
Q
Q
E
S
F
Site 139
S2259
C
T
P
E
Q
Q
E
S
F
G
G
P
D
A
C
Site 140
S2349
H
Y
E
L
C
G
D
S
C
P
G
S
C
P
S
Site 141
S2353
C
G
D
S
C
P
G
S
C
P
S
L
S
A
P
Site 142
S2356
S
C
P
G
S
C
P
S
L
S
A
P
E
G
C
Site 143
S2358
P
G
S
C
P
S
L
S
A
P
E
G
C
E
S
Site 144
S2365
S
A
P
E
G
C
E
S
A
C
R
E
G
C
V
Site 145
Y2398
G
C
L
H
D
D
R
Y
Y
P
L
G
Q
T
F
Site 146
Y2399
C
L
H
D
D
R
Y
Y
P
L
G
Q
T
F
Y
Site 147
T2404
R
Y
Y
P
L
G
Q
T
F
Y
P
G
P
G
C
Site 148
Y2406
Y
P
L
G
Q
T
F
Y
P
G
P
G
C
D
S
Site 149
S2413
Y
P
G
P
G
C
D
S
L
C
R
C
R
E
G
Site 150
S2424
C
R
E
G
G
E
V
S
C
E
P
S
S
C
G
Site 151
S2428
G
E
V
S
C
E
P
S
S
C
G
P
H
E
T
Site 152
S2429
E
V
S
C
E
P
S
S
C
G
P
H
E
T
C
Site 153
T2435
S
S
C
G
P
H
E
T
C
R
P
S
G
G
S
Site 154
S2439
P
H
E
T
C
R
P
S
G
G
S
L
G
C
V
Site 155
S2627
W
E
E
V
V
P
D
S
P
C
L
P
P
P
T
Site 156
T2634
S
P
C
L
P
P
P
T
C
P
P
G
S
E
G
Site 157
S2639
P
P
T
C
P
P
G
S
E
G
C
I
P
S
E
Site 158
S2645
G
S
E
G
C
I
P
S
E
E
C
P
P
E
L
Site 159
Y2739
E
C
P
Q
N
S
H
Y
E
L
C
A
D
T
C
Site 160
Y2794
G
C
Y
H
N
G
A
Y
Y
E
P
E
Q
T
V
Site 161
Y2795
C
Y
H
N
G
A
Y
Y
E
P
E
Q
T
V
L
Site 162
S2839
Q
P
S
G
G
I
L
S
C
V
N
K
D
P
C
Site 163
Y3157
T
C
P
E
N
S
H
Y
E
V
C
G
P
P
C
Site 164
Y3297
D
F
Q
G
T
C
E
Y
L
L
S
A
P
C
H
Site 165
Y3662
Q
A
S
G
D
P
H
Y
T
T
F
D
G
H
R
Site 166
T3664
S
G
D
P
H
Y
T
T
F
D
G
H
R
F
D
Site 167
T3835
S
P
C
L
P
P
P
T
C
P
P
G
S
A
G
Site 168
S3840
P
P
T
C
P
P
G
S
A
G
C
I
P
S
D
Site 169
S3846
G
S
A
G
C
I
P
S
D
K
C
P
P
E
L
Site 170
S4175
S
V
A
D
G
R
I
S
V
A
Q
G
A
S
K
Site 171
T4292
S
G
T
G
G
P
F
T
T
C
H
A
H
V
P
Site 172
S4760
P
V
S
C
P
S
L
S
A
P
E
G
C
E
S
Site 173
Y4800
G
C
L
H
D
G
R
Y
Y
P
L
G
E
V
F
Site 174
Y4801
C
L
H
D
G
R
Y
Y
P
L
G
E
V
F
Y
Site 175
Y4808
Y
P
L
G
E
V
F
Y
P
G
P
E
C
E
R
Site 176
T4866
N
G
G
I
H
Y
I
T
L
D
G
R
V
Y
D
Site 177
Y4872
I
T
L
D
G
R
V
Y
D
L
H
G
S
C
S
Site 178
S4896
K
P
G
D
E
D
F
S
I
V
L
E
K
N
A
Site 179
T4946
A
V
G
R
V
R
V
T
A
E
G
R
N
M
V
Site 180
S4973
G
D
A
H
L
L
M
S
I
P
S
P
F
R
G
Site 181
S5007
P
N
G
S
A
A
S
S
V
E
T
F
G
A
A
Site 182
S5020
A
A
W
R
A
P
G
S
S
K
G
C
G
E
G
Site 183
S5021
A
W
R
A
P
G
S
S
K
G
C
G
E
G
C
Site 184
Y5044
L
A
E
E
T
A
P
Y
E
S
N
E
A
C
G
Site 185
S5068
A
T
C
Q
A
V
L
S
P
S
E
Y
F
R
Q
Site 186
Y5072
A
V
L
S
P
S
E
Y
F
R
Q
C
V
Y
D
Site 187
Y5182
G
C
T
H
N
G
R
Y
L
P
V
N
S
S
L
Site 188
S5187
G
R
Y
L
P
V
N
S
S
L
L
T
S
D
C
Site 189
S5188
R
Y
L
P
V
N
S
S
L
L
T
S
D
C
S
Site 190
T5191
P
V
N
S
S
L
L
T
S
D
C
S
E
R
C
Site 191
S5192
V
N
S
S
L
L
T
S
D
C
S
E
R
C
S
Site 192
S5195
S
L
L
T
S
D
C
S
E
R
C
S
C
S
S
Site 193
S5199
S
D
C
S
E
R
C
S
C
S
S
S
S
G
L
Site 194
S5201
C
S
E
R
C
S
C
S
S
S
S
G
L
T
C
Site 195
S5202
S
E
R
C
S
C
S
S
S
S
G
L
T
C
Q
Site 196
S5203
E
R
C
S
C
S
S
S
S
G
L
T
C
Q
A
Site 197
T5245
S
V
G
A
N
L
T
T
F
D
G
A
R
G
A
Site 198
T5253
F
D
G
A
R
G
A
T
T
S
P
G
V
Y
E
Site 199
S5255
G
A
R
G
A
T
T
S
P
G
V
Y
E
L
S
Site 200
Y5259
A
T
T
S
P
G
V
Y
E
L
S
S
R
C
P
Site 201
S5262
S
P
G
V
Y
E
L
S
S
R
C
P
G
L
Q
Site 202
S5263
P
G
V
Y
E
L
S
S
R
C
P
G
L
Q
N
Site 203
Y5275
L
Q
N
T
I
P
W
Y
R
V
V
A
E
V
Q
Site 204
T5306
Q
D
G
M
V
T
L
T
P
N
K
G
V
W
V
Site 205
S5327
L
P
A
E
K
L
A
S
V
S
V
S
R
T
P
Site 206
S5329
A
E
K
L
A
S
V
S
V
S
R
T
P
D
G
Site 207
S5331
K
L
A
S
V
S
V
S
R
T
P
D
G
S
L
Site 208
S5337
V
S
R
T
P
D
G
S
L
L
V
R
Q
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation