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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCIN
Full Name:
Adseverin
Alias:
ADSV; KIAA1905; Scinderin
Type:
Cytoskeleton protein
Mass (Da):
80489
Number AA:
715
UniProt ID:
Q9Y6U3
International Prot ID:
IPI00002606
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005938
Uniprot
OncoNet
Molecular Function:
GO:0001786
GO:0003779
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006887
GO:0008064
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
Q
S
A
H
G
D
F
Y
V
G
D
A
Y
L
V
Site 2
T54
L
V
L
H
T
A
K
T
S
R
G
F
T
Y
H
Site 3
Y60
K
T
S
R
G
F
T
Y
H
L
H
F
W
L
G
Site 4
S71
F
W
L
G
K
E
C
S
Q
D
E
S
T
A
A
Site 5
S75
K
E
C
S
Q
D
E
S
T
A
A
A
I
F
T
Site 6
Y88
F
T
V
Q
M
D
D
Y
L
G
G
K
P
V
Q
Site 7
Y102
Q
N
R
E
L
Q
G
Y
E
S
N
D
F
V
S
Site 8
S104
R
E
L
Q
G
Y
E
S
N
D
F
V
S
Y
F
Site 9
S109
Y
E
S
N
D
F
V
S
Y
F
K
G
G
L
K
Site 10
Y110
E
S
N
D
F
V
S
Y
F
K
G
G
L
K
Y
Site 11
Y117
Y
F
K
G
G
L
K
Y
K
A
G
G
V
A
S
Site 12
T131
S
G
L
N
H
V
L
T
N
D
L
T
A
K
R
Site 13
T151
G
R
R
V
V
R
A
T
E
V
P
L
S
W
D
Site 14
S156
R
A
T
E
V
P
L
S
W
D
S
F
N
K
G
Site 15
Y175
I
D
L
G
T
E
I
Y
Q
W
C
G
S
S
C
Site 16
Y185
C
G
S
S
C
N
K
Y
E
R
L
K
A
N
Q
Site 17
Y199
Q
V
A
T
G
I
R
Y
N
E
R
K
G
R
S
Site 18
S244
D
D
I
I
A
D
I
S
N
R
K
M
A
K
L
Site 19
Y252
N
R
K
M
A
K
L
Y
M
V
S
D
A
S
G
Site 20
S255
M
A
K
L
Y
M
V
S
D
A
S
G
S
M
R
Site 21
T264
A
S
G
S
M
R
V
T
V
V
A
E
E
N
P
Site 22
T312
E
R
K
A
A
M
K
T
A
E
E
F
L
Q
Q
Site 23
Y322
E
F
L
Q
Q
M
N
Y
S
K
N
T
Q
I
Q
Site 24
T326
Q
M
N
Y
S
K
N
T
Q
I
Q
V
L
P
E
Site 25
T337
V
L
P
E
G
G
E
T
P
I
F
K
Q
F
F
Site 26
S353
D
W
R
D
K
D
Q
S
D
G
F
G
K
V
Y
Site 27
Y360
S
D
G
F
G
K
V
Y
V
T
E
K
V
A
Q
Site 28
S376
K
Q
I
P
F
D
A
S
K
L
H
S
S
P
Q
Site 29
S380
F
D
A
S
K
L
H
S
S
P
Q
M
A
A
Q
Site 30
S381
D
A
S
K
L
H
S
S
P
Q
M
A
A
Q
H
Site 31
S415
R
I
Q
V
D
Q
N
S
Y
G
E
F
Y
G
G
Site 32
Y416
I
Q
V
D
Q
N
S
Y
G
E
F
Y
G
G
D
Site 33
Y438
Y
P
R
G
Q
I
I
Y
T
W
Q
G
A
N
A
Site 34
T451
N
A
T
R
D
E
L
T
T
S
A
F
L
T
V
Site 35
T452
A
T
R
D
E
L
T
T
S
A
F
L
T
V
Q
Site 36
S474
Q
A
V
Q
I
R
V
S
Q
G
K
E
P
V
H
Site 37
S484
K
E
P
V
H
L
L
S
L
F
K
D
K
P
L
Site 38
Y494
K
D
K
P
L
I
I
Y
K
N
G
T
S
K
K
Site 39
S534
E
V
D
V
D
A
N
S
L
N
S
N
D
V
F
Site 40
Y551
K
L
P
Q
N
S
G
Y
I
W
V
G
K
G
A
Site 41
Y568
E
E
E
K
G
A
E
Y
V
A
S
V
L
K
C
Site 42
T577
A
S
V
L
K
C
K
T
L
R
I
Q
E
G
E
Site 43
S592
E
P
E
E
F
W
N
S
L
G
G
K
K
D
Y
Site 44
Y599
S
L
G
G
K
K
D
Y
Q
T
S
P
L
L
E
Site 45
T601
G
G
K
K
D
Y
Q
T
S
P
L
L
E
T
Q
Site 46
S602
G
K
K
D
Y
Q
T
S
P
L
L
E
T
Q
A
Site 47
Y617
E
D
H
P
P
R
L
Y
G
C
S
N
K
T
G
Site 48
S620
P
P
R
L
Y
G
C
S
N
K
T
G
R
F
V
Site 49
T623
L
Y
G
C
S
N
K
T
G
R
F
V
I
E
E
Site 50
S670
N
E
V
E
K
K
E
S
L
K
S
A
K
M
Y
Site 51
S673
E
K
K
E
S
L
K
S
A
K
M
Y
L
E
T
Site 52
Y677
S
L
K
S
A
K
M
Y
L
E
T
D
P
S
G
Site 53
S683
M
Y
L
E
T
D
P
S
G
R
D
K
R
T
P
Site 54
T689
P
S
G
R
D
K
R
T
P
I
V
I
I
K
Q
Site 55
T702
K
Q
G
H
E
P
P
T
F
T
G
W
F
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation