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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM169A
Full Name:
Protein FAM169A
Alias:
f169a; fam169a; family with sequence similarity 169, member a; kiaa0888
Type:
Mass (Da):
74936
Number AA:
670
UniProt ID:
Q9Y6X4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
V
D
M
L
E
N
C
S
H
E
E
L
E
N
S
Site 2
S19
S
H
E
E
L
E
N
S
A
E
D
Y
M
S
D
Site 3
Y23
L
E
N
S
A
E
D
Y
M
S
D
L
R
C
G
Site 4
S25
N
S
A
E
D
Y
M
S
D
L
R
C
G
D
P
Site 5
Y58
N
V
G
F
V
P
L
Y
G
G
D
Q
T
Q
K
Site 6
T96
A
I
D
D
I
V
K
T
S
V
P
S
R
E
G
Site 7
S97
I
D
D
I
V
K
T
S
V
P
S
R
E
G
L
Site 8
Y117
L
G
E
R
V
V
L
Y
V
L
N
R
I
I
Y
Site 9
Y124
Y
V
L
N
R
I
I
Y
R
K
Q
E
M
E
R
Site 10
Y144
L
C
H
S
S
T
D
Y
A
K
I
L
W
K
K
Site 11
Y158
K
G
E
A
I
G
F
Y
S
V
K
P
T
G
S
Site 12
S169
P
T
G
S
I
C
A
S
F
L
T
Q
S
Y
Q
Site 13
T182
Y
Q
L
P
V
L
D
T
M
F
L
R
K
K
Y
Site 14
Y189
T
M
F
L
R
K
K
Y
R
G
K
D
F
G
L
Site 15
T207
E
D
F
V
D
S
F
T
E
D
A
L
G
L
R
Site 16
Y215
E
D
A
L
G
L
R
Y
P
L
S
S
L
M
Y
Site 17
Y222
Y
P
L
S
S
L
M
Y
T
A
C
K
Q
Y
F
Site 18
T223
P
L
S
S
L
M
Y
T
A
C
K
Q
Y
F
E
Site 19
Y228
M
Y
T
A
C
K
Q
Y
F
E
K
Y
P
G
D
Site 20
Y232
C
K
Q
Y
F
E
K
Y
P
G
D
H
E
L
L
Site 21
Y249
V
E
G
V
G
H
W
Y
Q
R
I
P
V
T
R
Site 22
S269
A
L
K
I
L
A
L
S
Q
N
E
P
K
R
P
Site 23
S278
N
E
P
K
R
P
M
S
G
E
Y
G
P
A
S
Site 24
Y281
K
R
P
M
S
G
E
Y
G
P
A
S
V
P
E
Site 25
S285
S
G
E
Y
G
P
A
S
V
P
E
Y
E
A
R
Site 26
Y289
G
P
A
S
V
P
E
Y
E
A
R
T
E
D
N
Site 27
S298
A
R
T
E
D
N
Q
S
S
E
M
Q
L
T
I
Site 28
S299
R
T
E
D
N
Q
S
S
E
M
Q
L
T
I
D
Site 29
T304
Q
S
S
E
M
Q
L
T
I
D
S
L
K
D
A
Site 30
S307
E
M
Q
L
T
I
D
S
L
K
D
A
F
A
S
Site 31
T322
T
S
E
G
H
D
K
T
S
V
S
T
H
T
R
Site 32
S323
S
E
G
H
D
K
T
S
V
S
T
H
T
R
S
Site 33
T326
H
D
K
T
S
V
S
T
H
T
R
S
G
N
L
Site 34
S330
S
V
S
T
H
T
R
S
G
N
L
K
R
P
K
Site 35
S345
I
G
K
R
F
Q
D
S
E
F
S
S
S
Q
G
Site 36
S348
R
F
Q
D
S
E
F
S
S
S
Q
G
E
D
E
Site 37
S349
F
Q
D
S
E
F
S
S
S
Q
G
E
D
E
K
Site 38
S350
Q
D
S
E
F
S
S
S
Q
G
E
D
E
K
T
Site 39
T357
S
Q
G
E
D
E
K
T
S
Q
T
S
L
T
A
Site 40
S358
Q
G
E
D
E
K
T
S
Q
T
S
L
T
A
S
Site 41
S361
D
E
K
T
S
Q
T
S
L
T
A
S
I
N
K
Site 42
S365
S
Q
T
S
L
T
A
S
I
N
K
L
E
S
T
Site 43
S371
A
S
I
N
K
L
E
S
T
A
R
P
S
E
S
Site 44
T372
S
I
N
K
L
E
S
T
A
R
P
S
E
S
S
Site 45
S376
L
E
S
T
A
R
P
S
E
S
S
E
E
F
L
Site 46
S378
S
T
A
R
P
S
E
S
S
E
E
F
L
E
E
Site 47
S379
T
A
R
P
S
E
S
S
E
E
F
L
E
E
E
Site 48
S399
I
E
F
E
D
E
S
S
D
R
D
A
R
P
A
Site 49
T409
D
A
R
P
A
L
E
T
Q
P
Q
Q
E
K
Q
Site 50
S435
N
G
E
I
M
D
D
S
L
K
T
S
L
I
T
Site 51
S439
M
D
D
S
L
K
T
S
L
I
T
E
E
E
D
Site 52
S447
L
I
T
E
E
E
D
S
T
S
E
V
L
D
E
Site 53
T448
I
T
E
E
E
D
S
T
S
E
V
L
D
E
E
Site 54
S449
T
E
E
E
D
S
T
S
E
V
L
D
E
E
L
Site 55
S463
L
K
L
Q
P
F
N
S
S
E
D
S
T
N
L
Site 56
S467
P
F
N
S
S
E
D
S
T
N
L
V
P
L
V
Site 57
S478
V
P
L
V
V
E
S
S
K
P
P
E
V
D
A
Site 58
T489
E
V
D
A
P
D
K
T
P
R
I
P
D
S
E
Site 59
S495
K
T
P
R
I
P
D
S
E
M
L
M
D
E
G
Site 60
T503
E
M
L
M
D
E
G
T
S
D
E
K
G
H
M
Site 61
S515
G
H
M
E
E
K
L
S
L
L
P
R
K
K
A
Site 62
S526
R
K
K
A
H
L
G
S
S
D
N
V
A
T
M
Site 63
S527
K
K
A
H
L
G
S
S
D
N
V
A
T
M
S
Site 64
S534
S
D
N
V
A
T
M
S
N
E
E
R
S
D
G
Site 65
S539
T
M
S
N
E
E
R
S
D
G
G
F
P
N
S
Site 66
S546
S
D
G
G
F
P
N
S
V
I
A
E
F
S
E
Site 67
S552
N
S
V
I
A
E
F
S
E
E
P
V
S
E
N
Site 68
S557
E
F
S
E
E
P
V
S
E
N
L
S
P
N
T
Site 69
S561
E
P
V
S
E
N
L
S
P
N
T
T
S
S
L
Site 70
T565
E
N
L
S
P
N
T
T
S
S
L
E
D
Q
G
Site 71
S567
L
S
P
N
T
T
S
S
L
E
D
Q
G
E
E
Site 72
S577
D
Q
G
E
E
G
V
S
E
P
Q
E
T
S
T
Site 73
T582
G
V
S
E
P
Q
E
T
S
T
A
L
P
Q
S
Site 74
T584
S
E
P
Q
E
T
S
T
A
L
P
Q
S
S
L
Site 75
S602
E
L
E
D
V
P
F
S
Q
N
A
G
Q
K
N
Site 76
S611
N
A
G
Q
K
N
Q
S
E
E
Q
S
E
A
S
Site 77
S615
K
N
Q
S
E
E
Q
S
E
A
S
S
E
Q
L
Site 78
S618
S
E
E
Q
S
E
A
S
S
E
Q
L
D
Q
F
Site 79
S619
E
E
Q
S
E
A
S
S
E
Q
L
D
Q
F
T
Site 80
T626
S
E
Q
L
D
Q
F
T
Q
S
A
E
K
A
V
Site 81
S635
S
A
E
K
A
V
D
S
S
S
E
E
I
E
V
Site 82
S636
A
E
K
A
V
D
S
S
S
E
E
I
E
V
E
Site 83
S637
E
K
A
V
D
S
S
S
E
E
I
E
V
E
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation